Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity
Pang, Allan H., Green, Keith D., Chandrika, Nishad Thamban, Garzan, Atefeh, Punetha, Ankita, Holbrook, Selina Y.L., Willby, Melisa J., Posey, James E., Tsodikov, Oleg V., Garneau-Tsodikova, Sylvie
Published in European journal of medicinal chemistry (15.11.2022)
Published in European journal of medicinal chemistry (15.11.2022)
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Journal Article
Correlation between GyrA substitutions and ofloxacin, levofloxacin, and moxifloxacin cross-resistance in Mycobacterium tuberculosis
Willby, Melisa, Sikes, R David, Malik, Seidu, Metchock, Beverly, Posey, James E
Published in Antimicrobial agents and chemotherapy (01.09.2015)
Published in Antimicrobial agents and chemotherapy (01.09.2015)
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Journal Article
Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis
Garzan, Atefeh, Willby, Melisa J, Green, Keith D, Gajadeera, Chathurada S, Hou, Caixia, Tsodikov, Oleg V, Posey, James E, Garneau-Tsodikova, Sylvie
Published in Journal of medicinal chemistry (08.12.2016)
Published in Journal of medicinal chemistry (08.12.2016)
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Journal Article
Disparities in capreomycin resistance levels associated with the rrs A1401G mutation in clinical isolates of Mycobacterium tuberculosis
Reeves, Analise Z, Campbell, Patricia J, Willby, Melisa J, Posey, James E
Published in Antimicrobial agents and chemotherapy (01.01.2015)
Published in Antimicrobial agents and chemotherapy (01.01.2015)
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Journal Article
Acetylation by Eis and Deacetylation by Rv1151c of Mycobacterium tuberculosis HupB: Biochemical and Structural Insight
Green, Keith D, Biswas, Tapan, Pang, Allan H, Willby, Melisa J, Reed, Matthew S, Stuchlik, Olga, Pohl, Jan, Posey, James E, Tsodikov, Oleg V, Garneau-Tsodikova, Sylvie
Published in Biochemistry (Easton) (06.02.2018)
Published in Biochemistry (Easton) (06.02.2018)
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Journal Article
Structure-Guided Optimization of Inhibitors of Acetyltransferase Eis from Mycobacterium tuberculosis
Punetha, Ankita, Ngo, Huy X, Holbrook, Selina Y L, Green, Keith D, Willby, Melisa J, Bonnett, Shilah A, Krieger, Kyle, Dennis, Emily K, Posey, James E, Parish, Tanya, Tsodikov, Oleg V, Garneau-Tsodikova, Sylvie
Published in ACS chemical biology (19.06.2020)
Published in ACS chemical biology (19.06.2020)
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Journal Article
Antimycobacterial activity of DNA intercalator inhibitors of Mycobacterium tuberculosis primase DnaG
Gajadeera, Chathurada, Willby, Melisa J, Green, Keith D, Shaul, Pazit, Fridman, Micha, Garneau-Tsodikova, Sylvie, Posey, James E, Tsodikov, Oleg V
Published in Journal of antibiotics (01.03.2015)
Published in Journal of antibiotics (01.03.2015)
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Journal Article
Detection of Mycobacterium tuberculosis pncA Mutations by the Nipro Genoscholar PZA-TB II Assay Compared to Conventional Sequencing
Willby, Melisa J, Wijkander, Maria, Havumaki, Joshua, Johnson, Kartee, Werngren, Jim, Hoffner, Sven, Denkinger, Claudia M, Posey, James E
Published in Antimicrobial agents and chemotherapy (01.01.2018)
Published in Antimicrobial agents and chemotherapy (01.01.2018)
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Journal Article
Multiorgan WU Polyomavirus Infection in Bone Marrow Transplant Recipient
Siebrasse, Erica A, Nguyen, Nang L, Willby, Melisa J, Erdman, Dean D, Menegus, Marilyn A, Wang, David
Published in Emerging infectious diseases (01.01.2016)
Published in Emerging infectious diseases (01.01.2016)
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Journal Article
Human coronavirus in young children hospitalized for acute respiratory illness and asymptomatic controls
Prill, Mila M, Iwane, Marika K, Edwards, Kathryn M, Williams, John V, Weinberg, Geoffrey A, Staat, Mary A, Willby, Melisa J, Talbot, H Keipp, Hall, Caroline B, Szilagyi, Peter G, Griffin, Marie R, Curns, Aaron T, Erdman, Dean D
Published in The Pediatric infectious disease journal (01.03.2012)
Published in The Pediatric infectious disease journal (01.03.2012)
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Journal Article
Potent Inhibitors of Acetyltransferase Eis Overcome Kanamycin Resistance in Mycobacterium tuberculosis
Willby, Melisa J, Green, Keith D, Gajadeera, Chathurada S, Hou, Caixia, Tsodikov, Oleg V, Posey, James E, Garneau-Tsodikova, Sylvie
Published in ACS chemical biology (17.06.2016)
Published in ACS chemical biology (17.06.2016)
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Journal Article
Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from Mycobacterium tuberculosis to overcome kanamycin resistance
Punetha, Ankita, Green, Keith D., Garzan, Atefeh, Thamban Chandrika, Nishad, Willby, Melisa J., Pang, Allan H., Hou, Caixia, Holbrook, Selina Y. L., Krieger, Kyle, Posey, James E., Parish, Tanya, Tsodikov, Oleg V., Garneau-Tsodikova, Sylvie
Published in MedChemComm (17.11.2021)
Published in MedChemComm (17.11.2021)
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Journal Article
Expanded geographic distribution for two Legionella pneumophila sequence types of clinical concern
Hamlin, Jennafer A P, Kozak-Muiznieks, Natalia A, Mercante, Jeffrey W, Rishishwar, Lavanya, Norris, Emily T, Gaines, Anna B, Ishaq, Maliha K, Winchell, Jonas M, Willby, Melisa J
Published in mSphere (28.10.2024)
Published in mSphere (28.10.2024)
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Journal Article
Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis
Garzan, Atefeh, Willby, Melisa J, Green, Keith D, Tsodikov, Oleg V, Posey, James E, Garneau-Tsodikova, Sylvie
Published in ACS medicinal chemistry letters (08.12.2016)
Published in ACS medicinal chemistry letters (08.12.2016)
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Journal Article
Respiratory Viruses Associated Hospitalization among Children Aged <5 Years in Bangladesh: 2010-2014
Homaira, Nusrat, Luby, Stephen P, Hossain, Kamal, Islam, Kariul, Ahmed, Makhdum, Rahman, Mustafizur, Rahman, Ziaur, Paul, Repon C, Bhuiyan, Mejbah Uddin, Brooks, W Abdullah, Sohel, Badrul Munir, Banik, Kajal Chandra, Widdowson, Marc-Alain, Willby, Melisa, Rahman, Mahmudur, Bresee, Joseph, Ramirez, Katharine-Sturm, Azziz-Baumgartner, Eduardo
Published in PloS one (03.02.2016)
Published in PloS one (03.02.2016)
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Journal Article
Combating Enhanced Intracellular Survival (Eis)-Mediated Kanamycin Resistance of Mycobacterium tuberculosis by Novel Pyrrolo[1,5‑a]pyrazine-Based Eis Inhibitors
Garzan, Atefeh, Willby, Melisa J, Ngo, Huy X, Gajadeera, Chathurada S, Green, Keith D, Holbrook, Selina Y. L, Hou, Caixia, Posey, James E, Tsodikov, Oleg V, Garneau-Tsodikova, Sylvie
Published in ACS infectious diseases (14.04.2017)
Published in ACS infectious diseases (14.04.2017)
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Journal Article
Potent 1,2,4-Triazino[5,6b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis
Ngo, Huy X., Green, Keith D., Gajadeera, Chathurada S., Willby, Melisa J., Holbrook, Selina Y. L., Hou, Caixia, Garzan, Atefeh, Mayhoub, Abdelrahman S., Posey, James E., Tsodikov, Oleg. V., Garneau-Tsodikova, Sylvie
Published in ACS infectious diseases (08.06.2018)
Published in ACS infectious diseases (08.06.2018)
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Journal Article
Notes from the Field: Legionnaires Disease in a U.S. Traveler After Staying in a Private Vacation Rental House in the U.S. Virgin Islands - United States, February 2022
Mac, Valerie V, Labgold, Katie, Moline, Heidi L, Smith, Jessica C, Carroll, Jamaal, Clemmons, Nakia, Edens, Chris, Ellis, Brett, Harrison, Cosme, Henderson, Kelley C, Ishaq, Maliha K, Kozak-Muiznieks, Natalia A, Kunz, Jasen, Lawrence, Marlon, Lucas, Claressa E, Walker, Heather L, Willby, Melisa J, Ellis, Esther M
Published in MMWR. Morbidity and mortality weekly report (19.05.2023)
Published in MMWR. Morbidity and mortality weekly report (19.05.2023)
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Journal Article
Large Community Outbreak of Legionnaires Disease Potentially Associated with a Cooling Tower - Napa County, California, 2022
Grossmann, Nárjara V, Milne, Crystal, Martinez, Melinda R, Relucio, Karen, Sadeghi, Banafsheh, Wiley, Erica N, Holland, Samuel N, Rutschmann, Sarah, Vugia, Duc J, Kimura, Akiko, Crain, Chad, Akter, Farhima, Mukhopadhyay, Rituparna, Crandall, John, Shorrock, Meghann, Smith, Jessica C, Prasad, Namrata, Kahn, Rebecca, Barskey, Albert E, Lee, Sooji, Willby, Melisa J, Kozak-Muiznieks, Natalia A, Lucas, Claressa E, Henderson, Kelley C, Hamlin, Jennafer A P, Yang, Eungi, Clemmons, Nakia S, Ritter, Troy, Henn, Jennifer
Published in MMWR. Morbidity and mortality weekly report (08.12.2023)
Published in MMWR. Morbidity and mortality weekly report (08.12.2023)
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