In vitro/in vivo models for peptide oral absorption: comparison of Caco-2 cell permeability with rat intestinal absorption of renin inhibitory peptides
Conradi, R A, Wilkinson, K F, Rush, B D, Hilgers, A R, Ruwart, M J, Burton, P S
Published in Pharmaceutical research (01.12.1993)
Published in Pharmaceutical research (01.12.1993)
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Peptides are better absorbed from the lung than the gut in the rat
Hoover, J L, Rush, B D, Wilkinson, K F, Day, J S, Burton, P S, Vidmar, T J, Ruwart, M J
Published in Pharmaceutical research (01.08.1992)
Published in Pharmaceutical research (01.08.1992)
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Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors
Islam, I, Ng, K. Y, Chong, K. T, McQuade, T. J, Hui, J. O, Wilkinson, K. F, Rush, B. D, Ruwart, M. J, Borchardt, R. T, Fisher, J. F
Published in Journal of medicinal chemistry (01.01.1994)
Published in Journal of medicinal chemistry (01.01.1994)
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Journal Article
Desolvation energy: a major determinant of absorption, but not clearance, of peptides in rats
Karls, M S, Rush, B D, Wilkinson, K F, Vidmar, T J, Burton, P S, Ruwart, M J
Published in Pharmaceutical research (01.12.1991)
Published in Pharmaceutical research (01.12.1991)
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Peptidomimetic HIV protease inhibitors: phosphate prodrugs with improved biological activities
Chong, Kong Teck, Ruwart, Mary J, Hinshaw, Roger R, Wilkinson, Karen F, Rush, Bob D, Yancey, Mark F, Strohbach, Joseph W, Thaisrivongs, Suvit
Published in Journal of medicinal chemistry (20.08.1993)
Published in Journal of medicinal chemistry (20.08.1993)
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Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses
Brideau, Roger J., Knechtel, Mary L., Huang, Audris, Vaillancourt, Valerie A., Vera, Ellen E., Oien, Nancee L., Hopkins, Todd A., Wieber, Janet L., Wilkinson, Karen F., Rush, Bob D., Schwende, Francis J., Wathen, Michael W.
Published in Antiviral research (01.04.2002)
Published in Antiviral research (01.04.2002)
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Development of activity assays for high-volume evaluation of human immunodeficiency virus (HIV) protease inhibitors in rat serum: results with ditekiren
Wilkinson, K F, Rush, B D, Sharma, S K, Evans, D B, Ruwart, M J, Friis, J M, Bohanon, M J, Tomich, P K
Published in Pharmaceutical research (01.04.1993)
Published in Pharmaceutical research (01.04.1993)
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Hepatic protection by 16, 16-dimethyl prostaglandin E2 (DMPG) against acute aflatoxin B1-induced injury in the rat
Rush, B D, Wilkinson, K F, Nichols, N M, Ochoa, R, Brunden, M N, Ruwart, M J
Published in Prostaglandins (01.06.1989)
Published in Prostaglandins (01.06.1989)
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Development of a sensitive activity assay for high-volume evaluation of human renin inhibitory peptides in rat serum: results with U-71,038
Ruwart, M J, Sharma, S K, Harris, D W, Lakings, D B, Rush, B D, Wilkinson, K F, Cornette, J C, Evans, D B, Friis, J M, Cook, K J
Published in Pharmaceutical research (01.04.1990)
Published in Pharmaceutical research (01.04.1990)
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Structure-Based Design of Sulfonamide-Substituted Non-Peptidic HIV Protease Inhibitors
Skulnick, Harvey I, Johnson, Paul D, Howe, W. Jeffrey, Tomich, Paul K, Chong, Kong-Teck, Watenpaugh, Keith D, Janakiraman, Musiri N, Dolak, Lester A, McGrath, James P
Published in Journal of medicinal chemistry (01.12.1995)
Published in Journal of medicinal chemistry (01.12.1995)
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Use of Medium-Sized Cycloalkyl Rings To Enhance Secondary Binding: Discovery of a New Class of Human Immunodeficiency Virus (HIV) Protease Inhibitors
Romines, Karen R, Watenpaugh, Keith D, Tomich, Paul K, Howe, W. Jeffrey, Morris, Jeanette K, Lovasz, Kristine D, Mulichak, Anne M, Finzel, Barry C, Lynn, Janet C
Published in Journal of medicinal chemistry (01.05.1995)
Published in Journal of medicinal chemistry (01.05.1995)
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The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat
Ruwart, M J, Wilkinson, K F, Rush, B D, Vidmar, T J, Peters, K M, Henley, K S, Appelman, H D, Kim, K Y, Schuppan, D, Hahn, E G
Published in Hepatology (Baltimore, Md.) (01.11.1989)
Published in Hepatology (Baltimore, Md.) (01.11.1989)
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Structure-Based Design of HIV Protease Inhibitors: 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Non-peptidic Inhibitors
Thaisrivongs, Suvit, Tomich, Paul K, Watenpaugh, Keith D, Chong, Kong-Teck, Howe, W. Jeffrey, Yang, Chih-Ping, Strohbach, Joseph W, Turner, Steve R, McGrath, James P
Published in Journal of medicinal chemistry (01.09.1994)
Published in Journal of medicinal chemistry (01.09.1994)
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Journal Article
Flue Gas and Fly Ash
Sens, P. F., Wilkinson, J. K., Commission of the European Communities
Year of Publication 02.09.2003
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Year of Publication 02.09.2003
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STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS
THAISRIVONGS, S, TOMICH, PK, WATENPAUGH, KD, CHONG, KT, HOWE, WJ, YANG, CP, STROHBACH, JW, TURNER, MCGRATH, JP, BOHANON, MJ, LYNN, JC, MULICHAK, AM, SPINELLI, PA, HINSHAW, RR, PAGANO, PJ, MOON, JB, RUWART, MJ, WILKINSON, KF, RUSH, BD, ZIPP, GL, DALGA, RJ, SCHWENDE, FJ, HOWARD, GM, PADBURY, GE, TOTH, LN, ZHAO, ZY, KOEPLINGER, KA, KAKUK, TJ, COLE, SL, ZAYA, RM, PIPER, RC, JEFFREY, P
Published in Journal of medicinal chemistry (30.09.1994)
Published in Journal of medicinal chemistry (30.09.1994)
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