Structure–function relationships of human JmjC oxygenases—demethylases versus hydroxylases
Markolovic, Suzana, Leissing, Thomas M, Chowdhury, Rasheduzzaman, Wilkins, Sarah E, Lu, Xin, Schofield, Christopher J
Published in Current opinion in structural biology (01.12.2016)
Published in Current opinion in structural biology (01.12.2016)
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JMJD5 is a human arginyl C-3 hydroxylase
Wilkins, Sarah E., Islam, Md. Saiful, Gannon, Joan M., Markolovic, Suzana, Hopkinson, Richard J., Ge, Wei, Schofield, Christopher J., Chowdhury, Rasheduzzaman
Published in Nature communications (21.03.2018)
Published in Nature communications (21.03.2018)
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Targeting Protein-Protein Interactions in the HIF System
Wilkins, Sarah E., Abboud, Martine I., Hancock, Rebecca L., Schofield, Christopher J.
Published in ChemMedChem (19.04.2016)
Published in ChemMedChem (19.04.2016)
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Journal Article
Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications
Hsu, Kuo-Feng, Wilkins, Sarah E., Hopkinson, Richard J., Sekirnik, Rok, Flashman, Emily, Kawamura, Akane, McCullagh, James S.O., Walport, Louise J., Schofield, Christopher J.
Published in Epigenetics (02.01.2021)
Published in Epigenetics (02.01.2021)
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The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases
Roatsch, Martin, Hoffmann, Inga, Abboud, Martine I, Hancock, Rebecca L, Tarhonskaya, Hanna, Hsu, Kuo-Feng, Wilkins, Sarah E, Yeh, Tzu-Lan, Lippl, Kerstin, Serrer, Kerstin, Moneke, Isabelle, Ahrens, Theresa D, Robaa, Dina, Wenzler, Sandra, Barthes, Nicolas P. F, Franz, Henriette, Sippl, Wolfgang, Lassmann, Silke, Diederichs, Sven, Schleicher, Erik, Schofield, Christopher J, Kawamura, Akane, Schüle, Roland, Jung, Manfred
Published in ACS chemical biology (16.08.2019)
Published in ACS chemical biology (16.08.2019)
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Journal Article
Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases
Markolovic, Suzana, Wilkins, Sarah E., Schofield, Christopher J.
Published in The Journal of biological chemistry (21.08.2015)
Published in The Journal of biological chemistry (21.08.2015)
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Journal Article
PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia
Banh, Robert S., Iorio, Caterina, Marcotte, Richard, Xu, Yang, Cojocari, Dan, Rahman, Anas Abdel, Pawling, Judy, Zhang, Wei, Sinha, Ankit, Rose, Christopher M., Isasa, Marta, Zhang, Shuang, Wu, Ronald, Virtanen, Carl, Hitomi, Toshiaki, Habu, Toshiyuki, Sidhu, Sachdev S., Koizumi, Akio, Wilkins, Sarah E., Kislinger, Thomas, Gygi, Steven P., Schofield, Christopher J., Dennis, James W., Wouters, Bradly G., Neel, Benjamin G.
Published in Nature cell biology (01.07.2016)
Published in Nature cell biology (01.07.2016)
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Journal Article
Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability
Makena, Anne, Brem, Jürgen, Pfeffer, Inga, Geffen, Rebecca E J, Wilkins, Sarah E, Tarhonskaya, Hanna, Flashman, Emily, Phee, Lynette M, Wareham, David W, Schofield, Christopher J
Published in Journal of antimicrobial chemotherapy (01.02.2015)
Published in Journal of antimicrobial chemotherapy (01.02.2015)
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Journal Article
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
Markolovic, Suzana, Zhuang, Qinqin, Wilkins, Sarah E., Eaton, Charlotte D., Abboud, Martine I., Katz, Maximiliano J., McNeil, Helen E., Leśniak, Robert K., Hall, Charlotte, Struwe, Weston B., Konietzny, Rebecca, Davis, Simon, Yang, Ming, Ge, Wei, Benesch, Justin L. P., Kessler, Benedikt M., Ratcliffe, Peter J., Cockman, Matthew E., Fischer, Roman, Wappner, Pablo, Chowdhury, Rasheduzzaman, Coleman, Mathew L., Schofield, Christopher J.
Published in Nature chemical biology (01.07.2018)
Published in Nature chemical biology (01.07.2018)
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Journal Article
Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1
Feng, Tianshu, Yamamoto, Atsushi, Wilkins, Sarah E., Sokolova, Elizaveta, Yates, Luke A., Münzel, Martin, Singh, Pooja, Hopkinson, Richard J., Fischer, Roman, Cockman, Matthew E., Shelley, Jake, Trudgian, David C., Schödel, Johannes, McCullagh, James S.O., Ge, Wei, Kessler, Benedikt M., Gilbert, Robert J., Frolova, Ludmila Y., Alkalaeva, Elena, Ratcliffe, Peter J., Schofield, Christopher J., Coleman, Mathew L.
Published in Molecular cell (20.02.2014)
Published in Molecular cell (20.02.2014)
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An essential role for dNTP homeostasis following CDK-induced replication stress
Pai, Chen-Chun, Hsu, Kuo-Feng, Durley, Samuel C, Keszthelyi, Andrea, Kearsey, Stephen E, Rallis, Charalampos, Folkes, Lisa K, Deegan, Rachel, Wilkins, Sarah E, Pfister, Sophia X, De León, Nagore, Schofield, Christopher J, Bähler, Jürg, Carr, Antony M, Humphrey, Timothy C
Published in Journal of cell science (25.03.2019)
Published in Journal of cell science (25.03.2019)
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Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway
Chen, Da-Yuan, Fabrizio, Jacqueline-Alba, Wilkins, Sarah E, Dave, Keyur A, Gorman, Jeffrey J, Gleadle, Jonathan M, Fleming, Stephen B, Peet, Daniel J, Mercer, Andrew A
Published in Journal of virology (01.01.2017)
Published in Journal of virology (01.01.2017)
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Journal Article
Factor Inhibiting HIF (FIH) Recognizes Distinct Molecular Features within Hypoxia-inducible Factor-α (HIF-α) versus Ankyrin Repeat Substrates
Wilkins, Sarah E., Karttunen, Sarah, Hampton-Smith, Rachel J., Murchland, Iain, Chapman-Smith, Anne, Peet, Daniel J.
Published in The Journal of biological chemistry (16.03.2012)
Published in The Journal of biological chemistry (16.03.2012)
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Journal Article
YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase
Sekirnik, Rok, Wilkins, Sarah E., Bush, Jacob, Tarhonskaya, Hanna, Münzel, Martin, Hussein, Aayan, Flashman, Emily, Mohammed, Shabaz, McDonough, Michael A., Loenarz, Christoph, Schofield, Christopher J.
Published in Extremophiles : life under extreme conditions (01.05.2018)
Published in Extremophiles : life under extreme conditions (01.05.2018)
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Journal Article
Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
Markolovic, Suzana, Zhuang, Qinqin, Wilkins, Sarah E., Eaton, Charlotte D., Abboud, Martine I., Katz, Maximiliano J., McNeil, Helen E., Leśniak, Robert K., Hall, Charlotte, Struwe, Weston B., Konietzny, Rebecca, Davis, Simon, Yang, Ming, Ge, Wei, Benesch, Justin L. P., Kessler, Benedikt M., Ratcliffe, Peter J., Cockman, Matthew E., Fischer, Roman, Wappner, Pablo, Chowdhury, Rasheduzzaman, Coleman, Mathew L., Schofield, Christopher J.
Published in Nature chemical biology (01.10.2018)
Published in Nature chemical biology (01.10.2018)
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Journal Article
Decreased Self-Appraisal Accuracy on Cognitive Tests of Executive Functioning Is a Predictor of Decline in Mild Cognitive Impairment
Scherling, Carole S, Wilkins, Sarah E, Zakrezewski, Jessica, Kramer, Joel H, Miller, Bruce L, Weiner, Michael W, Rosen, Howard J
Published in Frontiers in aging neuroscience (04.07.2016)
Published in Frontiers in aging neuroscience (04.07.2016)
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Differences in hydroxylation and binding of Notch and HIF-1α demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1)
Wilkins, Sarah E., Hyvärinen, Jaana, Chicher, Johana, Gorman, Jeffrey J., Peet, Daniel J., Bilton, Rebecca L., Koivunen, Peppi
Published in The international journal of biochemistry & cell biology (01.07.2009)
Published in The international journal of biochemistry & cell biology (01.07.2009)
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Journal Article
Biochemical characterization of New Delhi metallo-[Beta]-lactamase variants reveals differences in protein stability
Makena, Anne, Brem, Jürgen, Pfeffer, Inga, Geffen, Rebecca E J, Wilkins, Sarah E, Tarhonskaya, Hanna, Flashman, Emily, Phee, Lynette M, Wareham, David W, Schofield, Christopher J
Published in Journal of antimicrobial chemotherapy (01.02.2015)
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Published in Journal of antimicrobial chemotherapy (01.02.2015)
Journal Article
PTP1B regulates non-mitochondrial oxygen consumption via RNF213 to promote tumour survival during hypoxia
Banh, Robert S., Iorio, Caterina, Marcotte, Richard, Xu, Yang, Cojocari, Dan, Rahman, Anas Abdel, Pawling, Judy, Zhang, Wei, Sinha, Ankit, Rose, Christopher M., Isasa, Marta, Zhang, Shuang, Wu, Ronald, Virtanen, Carl, Hitomi, Toshiaki, Habu, Toshiyuki, Sidhu, Sachdev S., Koizumi, Akio, Wilkins, Sarah E., Kislinger, Thomas, Gygi, Steven P., Schofield, Christopher J., Dennis, James W., Wouters, Bradly G., Neel, Benjamin G.
Published in Nature cell biology (20.06.2016)
Published in Nature cell biology (20.06.2016)
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