Boc and Gas1 Each Form Distinct Shh Receptor Complexes with Ptch1 and Are Required for Shh-Mediated Cell Proliferation
Izzi, Luisa, Lévesque, Martin, Morin, Steves, Laniel, Dominique, Wilkes, Brian C., Mille, Frédéric, Krauss, Robert S., McMahon, Andrew P., Allen, Benjamin L., Charron, Frédéric
Published in Developmental cell (14.06.2011)
Published in Developmental cell (14.06.2011)
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Protein Stability and Transcription Factor Complex Assembly Determined by the SCL-LMO2 Interaction
Lécuyer, Eric, Larivière, Simon, Sincennes, Marie-Claude, Haman, André, Lahlil, Rachid, Todorova, Margarita, Tremblay, Mathieu, Wilkes, Brian C., Hoang, Trang
Published in The Journal of biological chemistry (16.11.2007)
Published in The Journal of biological chemistry (16.11.2007)
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S-Nitrosylation of β-Catenin by eNOS-Derived NO Promotes VEGF-Induced Endothelial Cell Permeability
Thibeault, Sébastien, Rautureau, Yohann, Oubaha, Malika, Faubert, Denis, Wilkes, Brian C., Delisle, Chantal, Gratton, Jean-Philippe
Published in Molecular cell (13.08.2010)
Published in Molecular cell (13.08.2010)
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Single Amino Acid Substitution in the PC1/3 Propeptide Can Induce Significant Modifications of Its Inhibitory Profile toward Its Cognate Enzyme
Rabah, Nadia, Gauthier, Dany, Wilkes, Brian C., Gauthier, Daniel J., Lazure, Claude
Published in The Journal of biological chemistry (17.03.2006)
Published in The Journal of biological chemistry (17.03.2006)
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Photolabeling Identifies Position 172 of the Human AT1 Receptor as a Ligand Contact Point: Receptor-Bound Angiotensin II Adopts an Extended Structure
Boucard, Antony A, Wilkes, Brian C, Laporte, Stéphane A, Escher, Emanuel, Guillemette, Gaétan, Leduc, Richard
Published in Biochemistry (Easton) (15.08.2000)
Published in Biochemistry (Easton) (15.08.2000)
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[Dmt1]DALDA analogues with enhanced μ opioid agonist potency and with a mixed μ/κ opioid activity profile
Bai, Longxiang, Li, Ziyuan, Chen, Jiajia, Chung, Nga N., Wilkes, Brian C., Li, Tingyou, Schiller, Peter W.
Published in Bioorganic & medicinal chemistry (01.04.2014)
Published in Bioorganic & medicinal chemistry (01.04.2014)
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A Cyclic Tetrapeptide (“Cyclodal”) and Its Mirror-Image Isomer Are Both High-Affinity μ Opioid Receptor Antagonists
Weltrowska, Grazyna, Nguyen, Thi M.-D, Chung, Nga N, Wood, JodiAnne, Ma, Xiaoyu, Guo, Jason, Wilkes, Brian C, Ge, Yang, Laferrière, André, Coderre, Terence J, Schiller, Peter W
Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
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‘Carba’-carfentanil (trans isomer): A μ opioid receptor (MOR) partial agonist with a distinct binding mode
Weltrowska, Grazyna, Lemieux, Carole, Chung, Nga N., Guo, Jason J., Wilkes, Brian C., Schiller, Peter W.
Published in Bioorganic & medicinal chemistry (01.09.2014)
Published in Bioorganic & medicinal chemistry (01.09.2014)
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"Carba"-Analogues of Fentanyl are Opioid Receptor Agonists
Weltrowska, Grazyna, Chung, Nga N., Lemieux, Carole, Guo, Jianxin, Lu, Yixin, Wilkes, Brian C., Schiller, Peter W.
Published in Journal of medicinal chemistry (08.04.2010)
Published in Journal of medicinal chemistry (08.04.2010)
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A New Approach to Explore the Binding Space of Polysaccharide-Based Ligands: Selectin Antagonists
Calosso, Mickael, Charpentier, Daniel, Vaillancourt, Marc, Bencheqroun, Mohammed, St-Pierre, Gabrielle, Wilkes, Brian C, Guindon, Yvan
Published in ACS medicinal chemistry letters (13.12.2012)
Published in ACS medicinal chemistry letters (13.12.2012)
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N-terminal guanidinylation of TIPP (Tyr-Tic-Phe-Phe) peptides results in major changes of the opioid activity profile
Weltrowska, Grazyna, Nguyen, Thi M.-D., Chung, Nga N., Wilkes, Brian C., Schiller, Peter W.
Published in Bioorganic & medicinal chemistry letters (15.09.2013)
Published in Bioorganic & medicinal chemistry letters (15.09.2013)
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Equipotent enantiomers of cyclic opioid peptides at μ opioid receptor
Weltrowska, Grazyna, Nguyen, Thi M-D, Chung, Nga N, Wilkes, Brian C, Schiller, Peter W
Published in Peptide science (Hoboken, N.J.) (01.01.2019)
Published in Peptide science (Hoboken, N.J.) (01.01.2019)
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Cyclic Opioid Peptide Agonists and Antagonists Obtained Via Ring-Closing Metathesis
Berezowska, Irena, Lemieux, Carole, Chung, Nga N, Wilkes, Brian C, Schiller, Peter W
Published in Chemical biology & drug design (01.10.2009)
Published in Chemical biology & drug design (01.10.2009)
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Raising the Ceiling of Diastereoselectivity in Hydrogen Transfer on Acyclic Radicals
Denissova, Irina, Maretti, Luca, Wilkes, Brian C., Scaiano, J.C., Guindon, Yvan
Published in Journal of organic chemistry (20.03.2009)
Published in Journal of organic chemistry (20.03.2009)
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“Carba”-Analogues of Fentanyl are Opioid Receptor Agonists ‡ Dedicated to the memory of Ralph F. Hirschmann
Weltrowska, Grazyna, Chung, Nga N, Lemieux, Carole, Guo, Jianxin, Lu, Yixin, Wilkes, Brian C, Schiller, Peter W
Published in Journal of medicinal chemistry (08.04.2010)
Published in Journal of medicinal chemistry (08.04.2010)
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