National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities
Ricordi, Camillo, Goldstein, Julia S, Balamurugan, A N, Szot, Gregory L, Kin, Tatsuya, Liu, Chengyang, Czarniecki, Christine W, Barbaro, Barbara, Bridges, Nancy D, Cano, Jose, Clarke, William R, Eggerman, Thomas L, Hunsicker, Lawrence G, Kaufman, Dixon B, Khan, Aisha, Lafontant, David-Erick, Linetsky, Elina, Luo, Xunrong, Markmann, James F, Naji, Ali, Korsgren, Olle, Oberholzer, Jose, Turgeon, Nicole A, Brandhorst, Daniel, Chen, Xiaojuan, Friberg, Andrew S, Lei, Ji, Wang, Ling-Jia, Wilhelm, Joshua J, Willits, Jamie, Zhang, Xiaomin, Hering, Bernhard J, Posselt, Andrew M, Stock, Peter G, Shapiro, A M James, Chen, Xiaojuan
Published in Diabetes (New York, N.Y.) (01.11.2016)
Published in Diabetes (New York, N.Y.) (01.11.2016)
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Journal Article
Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes
Singh, Amar, Ramachandran, Sabarinathan, Graham, Melanie L, Daneshmandi, Saeed, Heller, David, Suarez-Pinzon, Wilma Lucia, Balamurugan, Appakalai N, Ansite, Jeffrey D, Wilhelm, Joshua J, Yang, Amy, Zhang, Ying, Palani, Nagendra P, Abrahante, Juan E, Burlak, Christopher, Miller, Stephen D, Luo, Xunrong, Hering, Bernhard J
Published in Nature communications (02.08.2019)
Published in Nature communications (02.08.2019)
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Journal Article
Mitochondrial Proton Leak Regulated by Cyclophilin D Elevates Insulin Secretion in Islets at Nonstimulatory Glucose Levels
Taddeo, Evan P, Alsabeeh, Nour, Baghdasarian, Siyouneh, Wikstrom, Jakob D, Ritou, Eleni, Sereda, Samuel, Erion, Karel, Li, Jin, Stiles, Linsey, Abdulla, Muhamad, Swanson, Zachary, Wilhelm, Joshua J, Bellin, Melena D, Kibbey, Richard G, Liesa, Marc, Shirihai, Orian S
Published in Diabetes (New York, N.Y.) (01.02.2020)
Published in Diabetes (New York, N.Y.) (01.02.2020)
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Journal Article
A new enzyme mixture to increase the yield and transplant rate of autologous and allogeneic human islet products
Balamurugan, A N, Loganathan, Gopalakrishnan, Bellin, Melena D, Wilhelm, Joshua J, Harmon, James, Anazawa, Takayuki, Soltani, Sajjad M, Radosevich, David M, Yuasa, Takeshi, Tiwari, Mukesh, Papas, Klearchos K, McCarthy, Robert, Sutherland, David E R, Hering, Bernhard J
Published in Transplantation (15.04.2012)
Published in Transplantation (15.04.2012)
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Journal Article
Successful human islet isolation and transplantation indicating the importance of class 1 collagenase and collagen degradation activity assay
Balamurugan, A N, Breite, Andrew G, Anazawa, Takayuki, Loganathan, Gopalakrishnan, Wilhelm, Joshua J, Papas, Klearchos K, Dwulet, Francis E, McCarthy, Robert C, Hering, Bernhard J
Published in Transplantation (27.04.2010)
Published in Transplantation (27.04.2010)
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Journal Article
Preoperative Computerized Tomography and Magnetic Resonance Imaging of the Pancreas Predicts Pancreatic Mass and Functional Outcomes After Total Pancreatectomy and Islet Autotransplant
Young, Michael C, Theis, Jake R, Hodges, James S, Dunn, Ty B, Pruett, Timothy L, Chinnakotla, Srinath, Walker, Sidney P, Freeman, Martin L, Trikudanathan, Guru, Arain, Mustafa, Robertson, Paul R, Wilhelm, Joshua J, Schwarzenberg, Sarah J, Bland, Barbara, Beilman, Gregory J, Bellin, Melena D
Published in Pancreas (01.08.2016)
Published in Pancreas (01.08.2016)
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Journal Article
Prediction of pancreatic tissue densities by an analytical test gradient system before purification maximizes human islet recovery for islet autotransplantation/allotransplantation
Anazawa, Takayuki, Matsumoto, Shuichiro, Yonekawa, Yukihide, Loganathan, Gopalakrishnan, Wilhelm, Joshua J, Soltani, Sajjad M, Papas, Klearchos K, Sutherland, David E R, Hering, Bernhard J, Balamurugan, A N
Published in Transplantation (15.03.2011)
Published in Transplantation (15.03.2011)
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Journal Article
Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
Chung, Katherine Minjee, Singh, Jaffarguriqbal, Lawres, Lauren, Dorans, Kimberly Judith, Garcia, Cathy, Burkhardt, Daniel B., Robbins, Rebecca, Bhutkar, Arjun, Cardone, Rebecca, Zhao, Xiaojian, Babic, Ana, Vayrynen, Sara A., Dias Costa, Andressa, Nowak, Jonathan A., Chang, Daniel T., Dunne, Richard F., Hezel, Aram F., Koong, Albert C., Wilhelm, Joshua J., Bellin, Melena D., Nylander, Vibe, Gloyn, Anna L., McCarthy, Mark I., Kibbey, Richard G., Krishnaswamy, Smita, Wolpin, Brian M., Jacks, Tyler, Fuchs, Charles S., Muzumdar, Mandar Deepak
Published in Cell (14.05.2020)
Published in Cell (14.05.2020)
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Journal Article
Identifying Effective Enzyme Activity Targets for Recombinant Class I and Class II Collagenase for Successful Human Islet Isolation
Balamurugan, Appakalai N, Green, Michael L, Breite, Andrew G, Loganathan, Gopalakrishnan, Wilhelm, Joshua J, Tweed, Benjamin, Vargova, Lenka, Lockridge, Amber, Kuriti, Manikya, Hughes, Michael G, Williams, Stuart K, Hering, Bernhard J, Dwulet, Francis E, McCarthy, Robert C
Published in Transplantation direct (01.01.2016)
Published in Transplantation direct (01.01.2016)
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Journal Article
Regulatory considerations of delayed autologous islet infusion in a 4‐year‐old child undergoing total pancreatectomy for chronic pancreatitis
Bellin, Melena D., Kim, Tae, Wilhelm, Joshua J., Schwarzenberg, Sarah Jane, Chinnakotla, Srinath
Published in American journal of transplantation (01.01.2020)
Published in American journal of transplantation (01.01.2020)
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Journal Article
Total Pancreatectomy With Islet Autotransplantation Resolves Pain in Young Children With Severe Chronic Pancreatitis
Bellin, Melena D., Forlenza, Gregory P., Majumder, Kaustav, Berger, Megan, Freeman, Martin L., Beilman, Gregory J., Dunn, Ty B., Pruett, Timothy L., Murati, Michael, Wilhelm, Joshua J., Cook, Marie, Sutherland, David E.R., Schwarzenberg, Sarah J., Chinnakotla, Srinath
Published in Journal of pediatric gastroenterology and nutrition (01.03.2017)
Published in Journal of pediatric gastroenterology and nutrition (01.03.2017)
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Journal Article
Circulating Unmethylated Insulin DNA As a Biomarker of Human Beta Cell Death: A Multi-laboratory Assay Comparison
Speake, Cate, Ylescupidez, Alyssa, Neiman, Daniel, Shemer, Ruth, Glaser, Benjamin, Tersey, Sarah A, Usmani-Brown, Sahar, Clark, Pamela, Wilhelm, Joshua J, Bellin, Melena D, Herold, Kevan C, Mirmira, Raghavendra G, Dor, Yuval, Evans-Molina, Carmella
Published in The journal of clinical endocrinology and metabolism (01.03.2020)
Published in The journal of clinical endocrinology and metabolism (01.03.2020)
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Journal Article
Progress in individualizing autologous islet isolation techniques for pediatric islet autotransplantation after total pancreatectomy in children for chronic pancreatitis
Wilhelm, Joshua J., Balamurugan, Appakalai N., Bellin, Melena D., Hodges, James S., Diaz, Jessica, Jane Schwarzenberg, Sarah, Swanson, Zachary A., Cook, Marie E., Downs, Elissa M., Sutherland, David E. R., Hering, Bernhard J., Chinnakotla, Srinath
Published in American journal of transplantation (01.02.2021)
Published in American journal of transplantation (01.02.2021)
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Journal Article
Pre-operative Sarcopenia Predicts Low Islet Cell Yield Following Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis
Trikudanathan, Guru, Feussom, Ghislaine, Teigen, Levi, Munigala, Satish, Price, Kathleen, Dirweesh, Ahmed, Wilhelm, Joshua J, Hering, Bernhard J, Kirchner, Varvara, Chinnakotla, Srinath, Beilman, Greg, Freeman, Martin L, Bellin, Melena D
Published in Journal of gastrointestinal surgery (01.10.2020)
Published in Journal of gastrointestinal surgery (01.10.2020)
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Journal Article
Age and Disease Duration Impact Outcomes of Total Pancreatectomy and Islet Autotransplant for PRSS1 Hereditary Pancreatitis
Bellin, Melena D, Prokhoda, Polina, Hodges, James S, Schwarzenberg, Sarah J, Freeman, Martin L, Dunn, Ty B, Wilhelm, Joshua J, Pruett, Timothy L, Kirchner, Varvara A, Beilman, Gregory J, Chinnakotla, Srinath
Published in Pancreas (01.04.2018)
Published in Pancreas (01.04.2018)
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Journal Article
Combination of pancreas volume and HbA1c level predicts islet yield in patients undergoing total pancreatectomy and islet autotransplantation
Nanno, Yoshihide, Wilhelm, Joshua J., Heller, David, Schat, Robben, Freeman, Martin L., Trikudanathan, Guru, Kirchner, Varvara A., Pruett, Timothy L., Beilman, Gregory J., Hering, Bernhard J., Bellin, Melena D.
Published in Clinical transplantation (01.08.2020)
Published in Clinical transplantation (01.08.2020)
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Journal Article
Islet size index as a predictor of outcomes in clinical islet autotransplantation
Suszynski, Thomas M, Wilhelm, Joshua J, Radosevich, David M, Balamurugan, A N, Sutherland, David E R, Beilman, Gregory J, Dunn, Ty B, Chinnakotla, Srinath, Pruett, Timothy L, Vickers, Selwyn M, Hering, Bernhard J, Papas, Klearchos K, Bellin, Melena D
Published in Transplantation (27.06.2014)
Published in Transplantation (27.06.2014)
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Journal Article
Total Pancreatectomy With Intraportal Islet Autotransplantation as a Treatment of Chronic Pancreatitis in Patients With CFTR Mutations
Colling, Kristin P, Bellin, Melena D, Schwarzenberg, Sarah J, Berry, Louise, Wilhelm, Joshua J, Dunn, Ty, Pruett, Timothy L, Sutherland, David E R, Chinnakotla, Srinath, Dunitz, Jordan M, Beilman, Greg J
Published in Pancreas (01.02.2018)
Published in Pancreas (01.02.2018)
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Journal Article
Autologous islet transplantation: challenges and lessons
Dunn, Ty B, Wilhelm, Joshua J, Bellin, Melena D, Pruett, Timothy L
Published in Current opinion in organ transplantation (01.08.2017)
Published in Current opinion in organ transplantation (01.08.2017)
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