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Published in Science (American Association for the Advancement of Science) (01.11.2019)
Published in Science (American Association for the Advancement of Science) (01.11.2019)
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Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
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The core spliceosome as target and effector of non-canonical ATM signalling
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Published in Nature (London) (02.07.2015)
Published in Nature (London) (02.07.2015)
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PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation
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Published in Cell stem cell (04.05.2017)
Published in Cell stem cell (04.05.2017)
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Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells
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Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2014)
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Snail Regulates MyoD Binding-Site Occupancy to Direct Enhancer Switching and Differentiation-Specific Transcription in Myogenesis
Soleimani, Vahab D., Yin, Hang, Jahani-Asl, Arezu, Ming, Hong, Kockx, Christel E.M., van Ijcken, Wilfred F.J., Grosveld, Frank, Rudnicki, Michael A.
Published in Molecular cell (10.08.2012)
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Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes
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Published in PloS one (17.09.2014)
Published in PloS one (17.09.2014)
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Redundant and specific roles of cohesin STAG subunits in chromatin looping and transcriptional control
Casa, Valentina, Moronta Gines, Macarena, Gade Gusmao, Eduardo, Slotman, Johan A, Zirkel, Anne, Josipovic, Natasa, Oole, Edwin, van IJcken, Wilfred F J, Houtsmuller, Adriaan B, Papantonis, Argyris, Wendt, Kerstin S
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Published in Genome research (01.04.2020)
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In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states
Neagu, Alex, van Genderen, Emiel, Escudero, Irene, Verwegen, Lucas, Kurek, Dorota, Lehmann, Johannes, Stel, Jente, Dirks, René A. M., van Mierlo, Guido, Maas, Alex, Eleveld, Cindy, Ge, Yang, den Dekker, Alexander. T., Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Modic, Miha, Drukker, Micha, Jansen, Joop H., Rivron, Nicolas C., Baart, Esther B., Marks, Hendrik, ten Berge, Derk
Published in Nature cell biology (01.05.2020)
Published in Nature cell biology (01.05.2020)
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Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness
Pachano, Tomas, Sánchez-Gaya, Víctor, Ealo, Thais, Mariner-Faulí, Maria, Bleckwehl, Tore, Asenjo, Helena G., Respuela, Patricia, Cruz-Molina, Sara, Muñoz-San Martín, María, Haro, Endika, van IJcken, Wilfred F. J., Landeira, David, Rada-Iglesias, Alvaro
Published in Nature genetics (01.07.2021)
Published in Nature genetics (01.07.2021)
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Butyrate inhibits human mast cell activation via epigenetic regulation of FcεRI‐mediated signaling
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Published in Allergy (Copenhagen) (01.08.2020)
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Two independent transcription initiation codes overlap on vertebrate core promoters
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Published in Nature (London) (20.03.2014)
Published in Nature (London) (20.03.2014)
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Fungal volatile compounds induce production of the secondary metabolite Sodorifen in Serratia plymuthica PRI-2C
Schmidt, Ruth, Jager, Victor de, Zühlke, Daniela, Wolff, Christian, Bernhardt, Jörg, Cankar, Katarina, Beekwilder, Jules, Ijcken, Wilfred van, Sleutels, Frank, Boer, Wietse de, Riedel, Katharina, Garbeva, Paolina
Published in Scientific reports (13.04.2017)
Published in Scientific reports (13.04.2017)
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Rao-Ruiz, Priyanka, Couey, Jonathan J., Marcelo, Ivo M., Bouwkamp, Christian G., Slump, Denise E., Matos, Mariana R., van der Loo, Rolinka J., Martins, Gabriela J., van den Hout, Mirjam, van IJcken, Wilfred F., Costa, Rui M., van den Oever, Michel C., Kushner, Steven A.
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Modeling the Pathological Long-Range Regulatory Effects of Human Structural Variation with Patient-Specific hiPSCs
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Published in Cell stem cell (02.05.2019)
Published in Cell stem cell (02.05.2019)
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Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up
Liu, Fan, Visser, Mijke, Duffy, David L., Hysi, Pirro G., Jacobs, Leonie C., Lao, Oscar, Zhong, Kaiyin, Walsh, Susan, Chaitanya, Lakshmi, Wollstein, Andreas, Zhu, Gu, Montgomery, Grant W., Henders, Anjali K., Mangino, Massimo, Glass, Daniel, Bataille, Veronique, Sturm, Richard A., Rivadeneira, Fernando, Hofman, Albert, van IJcken, Wilfred F. J., Uitterlinden, André G., Palstra, Robert-Jan T. S., Spector, Timothy D., Martin, Nicholas G., Nijsten, Tamar E. C., Kayser, Manfred
Published in Human genetics (01.08.2015)
Published in Human genetics (01.08.2015)
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Retrospective analysis of enhancer activity and transcriptome history
Boers, Ruben, Boers, Joachim, Tan, Beatrice, van Leeuwen, Marieke E., Wassenaar, Evelyne, Sanchez, Erlantz Gonzalez, Sleddens, Esther, Tenhagen, Yasha, Mulugeta, Eskeatnaf, Laven, Joop, Creyghton, Menno, Baarends, Willy, van IJcken, Wilfred F. J., Gribnau, Joost
Published in Nature biotechnology (01.11.2023)
Published in Nature biotechnology (01.11.2023)
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Enhancer-associated H3K4 methylation safeguards in vitro germline competence
Bleckwehl, Tore, Crispatzu, Giuliano, Schaaf, Kaitlin, Respuela, Patricia, Bartusel, Michaela, Benson, Laura, Clark, Stephen J., Dorighi, Kristel M., Barral, Antonio, Laugsch, Magdalena, van IJcken, Wilfred F. J., Manzanares, Miguel, Wysocka, Joanna, Reik, Wolf, Rada-Iglesias, Álvaro
Published in Nature communications (01.10.2021)
Published in Nature communications (01.10.2021)
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SPEN is required for Xist upregulation during initiation of X chromosome inactivation
Robert-Finestra, Teresa, Tan, Beatrice F., Mira-Bontenbal, Hegias, Timmers, Erika, Gontan, Cristina, Merzouk, Sarra, Giaimo, Benedetto Daniele, Dossin, François, van IJcken, Wilfred F. J., Martens, John W. M., Borggrefe, Tilman, Heard, Edith, Gribnau, Joost
Published in Nature communications (01.12.2021)
Published in Nature communications (01.12.2021)
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Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis
de Haan, Willeke, Dheedene, Wouter, Apelt, Katerina, Décombas-Deschamps, Sofiane, Vinckier, Stefan, Verhulst, Stefaan, Conidi, Andrea, Deffieux, Thomas, Staring, Michael W, Vandervoort, Petra, Caluwé, Ellen, Lox, Marleen, Mannaerts, Inge, Takagi, Tsuyoshi, Jaekers, Joris, Berx, Geert, Haigh, Jody, Topal, Baki, Zwijsen, An, Higashi, Yujiro, van Grunsven, Leo A, van IJcken, Wilfred F J, Mulugeta, Eskeatnaf, Tanter, Mickael, Lebrin, Franck P G, Huylebroeck, Danny, Luttun, Aernout
Published in Cardiovascular research (25.03.2022)
Published in Cardiovascular research (25.03.2022)
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