Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: Optimization of kinase selectivity and pharmacokinetics
Hornberger, Keith R., Chen, Xin, Crew, Andrew P., Kleinberg, Andrew, Ma, Lifu, Mulvihill, Mark J., Wang, Jing, Wilde, Victoria L., Albertella, Mark, Bittner, Mark, Cooke, Andrew, Kadhim, Salam, Kahler, Jennifer, Maresca, Paul, May, Earl, Meyn, Peter, Romashko, Darlene, Tokar, Brianna, Turton, Roy
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
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Journal Article
Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1
Hornberger, Keith R., Berger, Dan M., Crew, Andrew P., Dong, Hanqing, Kleinberg, Andrew, Li, An-Hu, Medeiros, Matthew R., Mulvihill, Mark J., Siu, Kam, Tarrant, James, Wang, Jing, Weng, Felix, Wilde, Victoria L., Albertella, Mark, Bittner, Mark, Cooke, Andrew, Gray, Michael J., Maresca, Paul, May, Earl, Meyn, Peter, Peick, William, Romashko, Darlene, Tanowitz, Michael, Tokar, Brianna
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
Get full text
Journal Article