The risk of extra‐colonic, extra‐endometrial cancer in the Lynch syndrome
Watson, Patrice, Vasen, Hans F.A., Mecklin, Jukka‐Pekka, Bernstein, Inge, Aarnio, Markku, Järvinen, Heikki J., Myrhøj, Torben, Sunde, Lone, Wijnen, Juul T., Lynch, Henry T.
Published in International journal of cancer (15.07.2008)
Published in International journal of cancer (15.07.2008)
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Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers
Jansen, Anne Ml, van Wezel, Tom, van den Akker, Brendy Ewm, Ventayol Garcia, Marina, Ruano, Dina, Tops, Carli Mj, Wagner, Anja, Letteboer, Tom Gw, Gómez-García, Encarna B, Devilee, Peter, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans
Published in European journal of human genetics : EJHG (01.07.2016)
Published in European journal of human genetics : EJHG (01.07.2016)
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The complexity of screening PMS2 in DNA isolated from formalin-fixed paraffin-embedded material
Jansen, Anne M L, Tops, Carli M J, Ruano, Dina, van Eijk, Ronald, Wijnen, Juul T, Ten Broeke, Sanne, Nielsen, Maartje, Hes, Frederik J, van Wezel, Tom, Morreau, Hans
Published in European journal of human genetics : EJHG (01.03.2020)
Published in European journal of human genetics : EJHG (01.03.2020)
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A genetic variant in telomerase reverse transcriptase (TERT) modifies cancer risk in Lynch syndrome patients harbouring pathogenic MSH2 variants
Wiik, Mariann Unhjem, Evans, Tiffany-Jane, Belhadj, Sami, Bolton, Katherine A., Dymerska, Dagmara, Jagmohan-Changur, Shantie, Capellá, Gabriel, Kurzawski, Grzegorz, Wijnen, Juul T., Valle, Laura, Vasen, Hans F. A., Lubinski, Jan, Scott, Rodney J., Talseth-Palmer, Bente A.
Published in Scientific reports (31.05.2021)
Published in Scientific reports (31.05.2021)
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Enrichment of Low Penetrance Susceptibility Loci in a Dutch Familial Colorectal Cancer Cohort
MIDDELDORP, Anneke, JAGMOHAN-CHANGUR, Shantie, WIJNEN, Juul T, MORREAU, Hans, VAN WEDEL, Tom, VAN EIJK, Ronald, TOPS, Carli, DEVILEE, Peter, VASEN, Hans F. A, HES, Frederik J, HOULSTON, Richard, TOMLINSON, Ian, HOUWING-DUISTERMAAT, Jeanine J
Published in Cancer epidemiology, biomarkers & prevention (01.11.2009)
Published in Cancer epidemiology, biomarkers & prevention (01.11.2009)
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Exome sequencing of germline DNA from non-BRCA1/2 familial breast cancer cases selected on the basis of aCGH tumor profiling
Hilbers, Florentine S, Meijers, Caro M, Laros, Jeroen F J, van Galen, Michiel, Hoogerbrugge, Nicoline, Vasen, Hans F A, Nederlof, Petra M, Wijnen, Juul T, van Asperen, Christi J, Devilee, Peter
Published in PloS one (31.01.2013)
Published in PloS one (31.01.2013)
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Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer
Elsayed, Fadwa A, Kets, C Marleen, Ruano, Dina, van den Akker, Brendy, Mensenkamp, Arjen R, Schrumpf, Melanie, Nielsen, Maartje, Wijnen, Juul T, Tops, Carli M, Ligtenberg, Marjolijn J, Vasen, Hans F A, Hes, Frederik J, Morreau, Hans, van Wezel, Tom
Published in European journal of human genetics : EJHG (01.08.2015)
Published in European journal of human genetics : EJHG (01.08.2015)
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A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3
Koessler, Thibaud, Chandler, Ian, Buch, Stephan, Agúndez, Jose AG, Caldés, Trinidad, Howarth, Kimberley, Walther, Axel, Ladero, Jose M, Morreau, Hans, Giles, Graham G, Cazier, Jean-Baptiste, Castells, Antoni, Maher, Eamonn R, Wood, Wendy, Försti, Asta, Southey, Melissa C, Broderick, Peter, Hopper, John L, de la Hoya, Miguel, Webb, Emily, Wijnen, Juul T, Aaltonen, Lauri, Dunlop, Malcolm G, John, Ulrich, Fielding, Sarah, Barnetson, Rebecca A, Barclay, Ella, Martin, Lynn, Bishop, D Timothy, Tuupanen, Sari, Tenesa, Albert, Jaeger, Emma, Cheng, K K, Niittymäki, Iina, Karhu, Auli, Schreiber, Stefan, Peto, Julian, Völzke, Henry, Schafmayer, Clemens, Luk, J, Vodicka, Pavel, Vijayakrishnan, Jayaram, Carracedo, Angel, Houlston, Richard S, Tomlinson, Ian PM, Rowan, Andrew, Ruiz-Ponte, Clara, Ho, Judy WC, Kemp, Zoe, Lipton, Lara, Sullivan, Kate, Penegar, Steven, Prendergast, James GD, Carvajal-Carmona, Luis, Hampe, Jochen, Sham, Pak C, Kerr, David, Pharoah, Paul, Severi, Gianluca, Campbell, Harry, Pittman, Alan M, Gray, Richard, Castellví-Bel, Sergi, Spain, Sarah, Domingo, Enric, Hemminki, Kari, Lubbe, Steven, Thomas, Huw, van Wezel, Tom, Naccarati, Alessio, Gorman, Maggie, Lucassen, Anneke, Farrington, Susan M, Qureshi, Mobshra, Evans, D Gareth R
Published in Nature genetics (01.05.2008)
Published in Nature genetics (01.05.2008)
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Distinct Patterns of Somatic Mosaicism in the APC Gene in Neoplasms From Patients With Unexplained Adenomatous Polyposis
Jansen, Anne M.L, Crobach, Stijn, Geurts-Giele, Willemina R.R, van den Akker, Brendy E.W.M, Garcia, Marina Ventayol, Ruano, Dina, Nielsen, Maartje, Tops, Carli M.J, Wijnen, Juul T, Hes, Frederik J, van Wezel, Tom, Dinjens, Winand N.M, Morreau, Hans
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2017)
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Validation and Implementation of BRCA1/2 Variant Screening in Ovarian Tumor Tissue
de Jonge, Marthe M., Ruano, Dina, van Eijk, Ronald, van der Stoep, Nienke, Nielsen, Maartje, Wijnen, Juul T., ter Haar, Natalja T., Baalbergen, Astrid, Bos, Monique E.M.M., Kagie, Marjolein J., Vreeswijk, Maaike P.G., Gaarenstroom, Katja N., Kroep, Judith R., Smit, Vincent T.H.B.M., Bosse, Tjalling, van Wezel, Tom, van Asperen, Christi J.
Published in The Journal of molecular diagnostics : JMD (01.09.2018)
Published in The Journal of molecular diagnostics : JMD (01.09.2018)
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Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ
Pahl, Jens H W, Kwappenberg, Kitty M C, Varypataki, Eleni M, Santos, Susy J, Kuijjer, Marieke L, Mohamed, Susan, Wijnen, Juul T, van Tol, Maarten J D, Cleton-Jansen, Anne-Marie, Egeler, R Maarten, Jiskoot, Wim, Lankester, Arjan C, Schilham, Marco W
Published in Journal of experimental & clinical cancer research (10.03.2014)
Published in Journal of experimental & clinical cancer research (10.03.2014)
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Intronic variants in BRCA1 and BRCA2 that affect RNA splicing can be reliably selected by splice-site prediction programs
Vreeswijk, Maaike P.G, Kraan, Jaennelle N, van der Klift, Heleen M, Vink, Geraldine R, Cornelisse, Cees J, Wijnen, Juul T, Bakker, Egbert, van Asperen, Christi J, Devilee, Peter
Published in Human mutation (2009)
Published in Human mutation (2009)
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RNA analysis of cancer predisposing genes in formalin-fixed paraffin-embedded tissue determines aberrant splicing
Jansen, Anne Ml, van der Klift, Heleen M, Roos, Marieke Ae, van Eendenburg, Jaap Dh, Tops, Carli Mj, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans, van Wezel, Tom
Published in European journal of human genetics : EJHG (01.08.2018)
Published in European journal of human genetics : EJHG (01.08.2018)
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Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia
Schubert, Stephanie A, Ruano, Dina, Elsayed, Fadwa A, Boot, Arnoud, Crobach, Stijn, Sarasqueta, Arantza Farina, Wolffenbuttel, Bruce, van der Klauw, Melanie M, Oosting, Jan, Tops, Carli M, van Eijk, Ronald, Vasen, Hans Fa, Vossen, Rolf Ham, Nielsen, Maartje, Castellví-Bel, Sergi, Ruiz-Ponte, Clara, Tomlinson, Ian, Dunlop, Malcolm G, Vodicka, Pavel, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans, de Miranda, Noel Fcc, Sijmons, Rolf H, van Wezel, Tom
Published in British journal of cancer (23.01.2018)
Published in British journal of cancer (23.01.2018)
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A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer
Middeldorp, Anneke, Jagmohan-Changur, Shantie, Helmer, Quinta, van der Klift, Heleen M, Tops, Carli M J, Vasen, Hans F A, Devilee, Peter, Morreau, Hans, Houwing-Duistermaat, Jeanine J, Wijnen, Juul T, van Wezel, Tom
Published in BMC cancer (12.01.2007)
Published in BMC cancer (12.01.2007)
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Rare variants in XRCC2 as breast cancer susceptibility alleles
Hilbers, Florentine S, Wijnen, Juul T, Hoogerbrugge, Nicoline, Oosterwijk, Jan C, Collee, Margriet J, Peterlongo, Paolo, Radice, Paolo, Manoukian, Siranoush, Feroce, Irene, Capra, Fabio, Couch, Fergus J, Wang, Xianshu, Guidugli, Lucia, Offit, Kenneth, Shah, Sohela, Campbell, Ian G, Thompson, Ella R, James, Paul A, Trainer, Alison H, Gracia, Javier, Benitez, Javier, van Asperen, Christi J, Devilee, Peter
Published in Journal of medical genetics (01.10.2012)
Published in Journal of medical genetics (01.10.2012)
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Combined analysis of three lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers
Talseth‐Palmer, Bente A., Wijnen, Juul T., Brenne, Ingvild S., Jagmohan‐Changur, Shantie, Barker, Daniel, Ashton, Katie A., Tops, Carli M., Evans, Tiffany‐Jane, McPhillips, Mary, Groombridge, Claire, Suchy, Janina, Kurzawski, Grzegorz, Spigelman, Allan, Møller, Pål, Morreau, Hans M., Van Wezel, Tom, Lubinski, Jan, Vasen, Hans F.A., Scott, Rodney J.
Published in International journal of cancer (01.04.2013)
Published in International journal of cancer (01.04.2013)
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Splicing analysis for exonic and intronic mismatch repair gene variants associated with Lynch syndrome confirms high concordance between minigene assays and patient RNA analyses
Klift, Heleen M., Jansen, Anne M. L., Steenstraten, Niki, Bik, Elsa C., Tops, Carli M. J., Devilee, Peter, Wijnen, Juul T.
Published in Molecular genetics & genomic medicine (01.07.2015)
Published in Molecular genetics & genomic medicine (01.07.2015)
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