Force-induced motions of the PIEZO1 blade probed with fluorimetry
Ozkan, Alper D., Wijerathne, Tharaka D., Gettas, Tina, Lacroix, Jérôme J.
Published in Cell reports (Cambridge) (29.08.2023)
Published in Cell reports (Cambridge) (29.08.2023)
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Journal Article
Energetic destabilization of shut states underpins the membrane stretch dependent activation of Piezo1
Wijerathne, Tharaka D., Ozkan, Alper D., Lacroix, Jerome J.
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Structural and thermodynamic framework for PIEZO1 modulation by small molecules
Jiang, Wenjuan, Wijerathne, Tharaka D, Zhang, Han, Lin, Yi-Chun, Jo, Sunhwan, Im, Wonpil, Lacroix, Jerome J, Luo, Yun L
Published in Proceedings of the National Academy of Sciences - PNAS (12.12.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (12.12.2023)
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Journal Article
Rationale design of novel PIEZO1 modulators
Jiang, Wenjuan, Wijerathne, Tharaka D., Zhang, Han, Lin, Yi-Chun, Im, Wonpil, Lacroix, Jerome J., Lyna Luo, Yun
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Microscopic mechanism of PIEZO1 activation by pressure-induced membrane stretch
Wijerathne, Tharaka D, Ozkan, Alper D, Lacroix, Jérôme J
Published in The Journal of general physiology (01.05.2023)
Published in The Journal of general physiology (01.05.2023)
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Journal Article
Thermodynamic and structural bases for Yoda1-mediated Piezo1 activation
Wijerathne, Tharaka D., Ozkan, Alper D., Lacroix, Jerome J.
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Long-range retrograde mechanical coupling in the PIEZO1 channel
Ozkan, Alper D., Wijerathne, Tharaka D., Lacroix, Jerome J.
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Intermolecular Cooperative Gating in Piezo1 Channels
Wijerathne, Tharaka D., Ozkan, Alper D., Lacroix, Jerome J.
Published in Biophysical journal (12.02.2021)
Published in Biophysical journal (12.02.2021)
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Journal Article
Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology
Bertaccini, Gabriella A, Casanellas, Ignasi, Evans, Elizabeth L, Nourse, Jamison L, Dickinson, George D, Liu, Gaoxiang, Seal, Sayan, Ly, Alan T, Holt, Jesse R, Wijerathne, Tharaka D, Yan, Shijun, Hui, Elliot E, Lacroix, Jerome J, Panicker, Mitradas M, Upadhyayula, Srigokul, Parker, Ian, Pathak, Medha M
Published in bioRxiv (18.09.2024)
Published in bioRxiv (18.09.2024)
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Journal Article
PIEZO1 discriminates mechanical stimuli
Ozkan, Alper D, Wijerathne, Tharaka D, Gettas, Tina, Jerome Jacques Lacroix
Published in bioRxiv (27.10.2022)
Published in bioRxiv (27.10.2022)
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