Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy
Wijerathna, Sanath R, Ahmad, Md Faiz, Xu, Hai, Fairman, James W, Zhang, Andrew, Kaushal, Prem Singh, Wan, Qun, Kiser, Jianying, Dealwis, Chris G
Published in Pharmaceuticals (13.10.2011)
Published in Pharmaceuticals (13.10.2011)
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Book Review
Structure‐Based Design, Synthesis, and Evaluation of 2′‐(2‐Hydroxyethyl)‐2′‐deoxyadenosine and the 5′‐Diphosphate Derivative as Ribonucleotide Reductase Inhibitors
Sun, Dianqing, Xu, Hai, Wijerathna, Sanath R., Dealwis, Chris, Lee, Richard E.
Published in ChemMedChem (05.10.2009)
Published in ChemMedChem (05.10.2009)
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Inhibition of yeast ribonucleotide reductase by Sml1 depends on the allosteric state of the enzyme
Misko, Tessianna A., Wijerathna, Sanath R., Radivoyevitch, Tomas, Berdis, Anthony J., Ahmad, Md. Faiz, Harris, Michael E., Dealwis, Chris G.
Published in FEBS letters (01.06.2016)
Published in FEBS letters (01.06.2016)
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Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase
Ahmad, Md. Faiz, Kaushal, Prem Singh, Wan, Qun, Wijerathna, Sanath R., An, Xiuxiang, Huang, Mingxia, Dealwis, Chris Godfrey
Published in Journal of molecular biology (22.06.2012)
Published in Journal of molecular biology (22.06.2012)
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The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
Xu, Hai, Fairman, James W, Wijerathna, Sanath R, Kreischer, Nathan R, LaMacchia, John, Helmbrecht, Elizabeth, Cooperman, Barry S, Dealwis, Chris
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
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Structure-based Design, Synthesis, and Evaluation of 2′-(2-Hydroxyethyl)-2′-Deoxyadenosine and Its 5′-Diphosphate as Novel Ribonucleotide Reductase Inhibitors
Sun, Dianqing, Xu, Hai, Wijerathna, Sanath, R., Dealwis, Chris, Lee, Richard E.
Published in ChemMedChem (01.10.2009)
Published in ChemMedChem (01.10.2009)
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