Preparation of the hypoxia imaging PET tracer [ 18F]FAZA: reaction parameters and automation
Reischl, G., Ehrlichmann, W., Bieg, C., Solbach, C., Kumar, P., Wiebe, L.I., Machulla, H.-J.
Published in Applied radiation and isotopes (01.06.2005)
Published in Applied radiation and isotopes (01.06.2005)
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Novel Approaches for Designing 5-O-Ester Prodrugs of 3-Azido-2,3-dideoxythymidine (AZT)
PARANG, Keykavous, WIEBE, Leonard I, KNAUS, Edward E
Published in Current medicinal chemistry (01.10.2000)
Published in Current medicinal chemistry (01.10.2000)
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Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer
DEGREVE, B, ANDREI, G, BALZARINI, J, IZQUIERDO, M, PIETTE, J, MORIN, K, KNAUS, E. E, WIEBE, L. I, BASRAH, I, WALKERS, R. T, DE CLERCQ, E
Published in Gene therapy (01.10.1997)
Published in Gene therapy (01.10.1997)
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Chiral Synthesis of 4-[1-(2-Deoxy-β-l-ribofuranosyl)] Derivatives of 2-Substituted 5-Fluoroaniline: “Cytosine Replacement” Analogues of Deoxy-β-l-cytidine
Wang, Zhi-Xian, Wiebe, Leonard I, Balzarini, Jan, De Clercq, Erik, Knaus, Edward E
Published in Journal of organic chemistry (29.12.2000)
Published in Journal of organic chemistry (29.12.2000)
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Reporter gene imaging: effects of ganciclovir treatment on nucleoside uptake, hypoxia and perfusion in a murine gene therapy tumour model that expresses herpes simplex type-1 thymidine kinase
Morin, K W, Knaus, E E, Wiebe, L I, Xia, H, McEwan, A J
Published in Nuclear medicine communications (01.02.2000)
Published in Nuclear medicine communications (01.02.2000)
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Imaging Tumor Hypoxia and Tumor Perfusion
Groshar, David, McEwan, Alexander J.B, Parliament, Matthew B, Urtasun, Raul C, Golberg, Lori E, Hoskinson, Michael, Mercer, John R, Mannan, Rezaul H, Wiebe, Leonard I, Chapman, J. Donald
Published in The Journal of nuclear medicine (1978) (01.06.1993)
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Published in The Journal of nuclear medicine (1978) (01.06.1993)
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Synthesis and Cellular Uptake of 2‘-Substituted Analogues of (E)-5-(2-[125I]Iodovinyl)-2‘-deoxyuridine in Tumor Cells Transduced with the Herpes Simplex Type-1 Thymidine Kinase Gene. Evaluation as Probes for Monitoring Gene Therapy
Morin, Kevin W, Atrazheva, Elena D, Knaus, Edward E, Wiebe, Leonard I
Published in Journal of medicinal chemistry (04.07.1997)
Published in Journal of medicinal chemistry (04.07.1997)
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Radioiodinated 1-(5-Iodo-5-deoxy-{beta}-D-arabinofuranosyl)-2-nitroimidazole (Iodoazomycin Arabinoside: IAZA): A Novel Marker of Tissue Hypoxia
Mannan, Rezaul H, Somayaji, Vijayalakashmi V, Lee, Jane, Mercer, John R, Chapman, J. Donald, Wiebe, Leonard I
Published in The Journal of nuclear medicine (1978) (01.09.1991)
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Published in The Journal of nuclear medicine (1978) (01.09.1991)
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A rapid and simple assay to determine the blood and urine concentrations of 1-(5-[ 123/125I]iodo-5-deoxyarabinofuranosyl)-2-nitroimidazole, a hypoxic cell marker
Stypinski, D, Wiebe, L.I, Mercer, J.R
Published in Journal of pharmaceutical and biomedical analysis (01.02.1998)
Published in Journal of pharmaceutical and biomedical analysis (01.02.1998)
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Conference Proceeding
SYNTHESIS OF 1-(2-DEOXY-β-D- RIBOFURANOSYL)-2,4-DIFLUORO-5-SUBSTITUTED-BENZENE THYMIDINE MIMICS, SOME RELATED α-ANOMERS, AND THEIR EVALUATION AS ANTIVIRAL AND ANTICANCER AGENTS
Wang, Zhi-Xian, Duan, Weili, Wiebe, Leonard I., Balzarini, Jan, De Clercq, Erik, Knaus, Edward E.
Published in Nucleosides, nucleotides & nucleic acids (01.01.2001)
Published in Nucleosides, nucleotides & nucleic acids (01.01.2001)
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Identification of hypoxic regions in traumatic brain injury
Vinjamuri, S, O'Driscoll, K, Maltby, P, McEwan, A J, Wiebe, L I, Critchley, M
Published in Clinical nuclear medicine (01.11.1999)
Published in Clinical nuclear medicine (01.11.1999)
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