Structural basis for allosteric PARP-1 retention on DNA breaks
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Published in Science (American Association for the Advancement of Science) (03.04.2020)
Published in Science (American Association for the Advancement of Science) (03.04.2020)
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The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
Krastev, Dragomir B, Li, Shudong, Sun, Yilun, Wicks, Andrew J, Hoslett, Gwendoline, Weekes, Daniel, Badder, Luned M, Knight, Eleanor G, Marlow, Rebecca, Pardo, Mercedes Calvo, Yu, Lu, Talele, Tanaji T, Bartek, Jiri, Choudhary, Jyoti S, Pommier, Yves, Pettitt, Stephen J, Tutt, Andrew N J, Ramadan, Kristijan, Lord, Christopher J
Published in Nature cell biology (01.01.2022)
Published in Nature cell biology (01.01.2022)
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Opinion: PARP inhibitors in cancer-what do we still need to know?
Wicks, Andrew J, Krastev, Dragomir B, Pettitt, Stephen J, Tutt, Andrew N J, Lord, Christopher J
Published in Open biology (27.07.2022)
Published in Open biology (27.07.2022)
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Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency
Bajrami, Ilirjana, Walker, Callum, Krastev, Dragomir B, Weekes, Daniel, Song, Feifei, Wicks, Andrew J, Alexander, John, Haider, Syed, Brough, Rachel, Pettitt, Stephen J, Tutt, Andrew N J, Lord, Christopher J
Published in Communications biology (08.11.2021)
Published in Communications biology (08.11.2021)
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PARP Inhibitors - Trapped in a Toxic Love Affair
Krastev, Dragomir B, Wicks, Andrew J, Lord, Christopher J
Published in Cancer research (Chicago, Ill.) (15.11.2021)
Published in Cancer research (Chicago, Ill.) (15.11.2021)
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