Catalytic activation of a single C-F bond in trifluoromethyl arenes
Dang, Hester, Whittaker, Aaron M, Lalic, Gojko
Published in Chemical science (Cambridge) (01.01.2016)
Published in Chemical science (Cambridge) (01.01.2016)
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Nine-Step Stereoselective Synthesis of Islatravir from Deoxyribose
Nawrat, Christopher C, Whittaker, Aaron M, Huffman, Mark A, McLaughlin, Mark, Cohen, Ryan D, Andreani, Teresa, Ding, Bangwei, Li, Hongming, Weisel, Mark, Tschaen, David M
Published in Organic letters (20.03.2020)
Published in Organic letters (20.03.2020)
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Development of a Commercial Manufacturing Route to 2‑Fluoroadenine, The Key Unnatural Nucleobase of Islatravir
Hong, Cynthia M, Xu, Yingju, Chung, John Y. L, Schultz, Danielle M, Weisel, Mark, Varsolona, Richard J, Zhong, Yong-Li, Purohit, Akasha K, He, Cyndi Q, Gauthier, Donald R, Humphrey, Guy R, Maloney, Kevin M, Lévesque, François, Wang, Zhixun, Whittaker, Aaron M, Sirota, Eric, McMullen, Jonathan P
Published in Organic process research & development (19.03.2021)
Published in Organic process research & development (19.03.2021)
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Photoactivated Uranyl Ion Produces Single Strand Breaks in Plasmid DNA
George, Shannon A, Whittaker, Aaron M, Stearns, Diane M
Published in Chemical research in toxicology (21.11.2011)
Published in Chemical research in toxicology (21.11.2011)
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Design of an in vitro biocatalytic cascade for the manufacture of islatravir
Huffman, Mark A, Fryszkowska, Anna, Alvizo, Oscar, Borra-Garske, Margie, Campos, Kevin R, Canada, Keith A, Devine, Paul N, Duan, Da, Forstater, Jacob H, Grosser, Shane T, Halsey, Holst M, Hughes, Gregory J, Jo, Junyong, Joyce, Leo A, Kolev, Joshua N, Liang, Jack, Maloney, Kevin M, Mann, Benjamin F, Marshall, Nicholas M, McLaughlin, Mark, Moore, Jeffrey C, Murphy, Grant S, Nawrat, Christopher C, Nazor, Jovana, Novick, Scott, Patel, Niki R, Rodriguez-Granillo, Agustina, Robaire, Sandra A, Sherer, Edward C, Truppo, Matthew D, Whittaker, Aaron M, Verma, Deeptak, Xiao, Li, Xu, Yingju, Yang, Hao
Published in Science (American Association for the Advancement of Science) (06.12.2019)
Published in Science (American Association for the Advancement of Science) (06.12.2019)
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Synthesis of Islatravir Enabled by a Catalytic, Enantioselective Alkynylation of a Ketone
Patel, Niki R., Nawrat, Christopher C., McLaughlin, Mark, Xu, Yingju, Huffman, Mark A., Yang, Hao, Li, Hongming, Whittaker, Aaron M., Andreani, Teresa, Levesque, Francois, Fryszkowska, Anna, Brunskill, Andrew, Tschaen, David M., Maloney, Kevin M.
Published in Organic letters (19.06.2020)
Published in Organic letters (19.06.2020)
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Biocatalytic oxidation of alcohols using galactose oxidase and a manganese() activator for the synthesis of islatravir
Johnson, Heather C, Zhang, Shaoguang, Fryszkowska, Anna, Ruccolo, Serge, Robaire, Sandra A, Klapars, Artis, Patel, Niki R, Whittaker, Aaron M, Huffman, Mark A, Strotman, Neil A
Published in Organic & biomolecular chemistry (25.02.2021)
Published in Organic & biomolecular chemistry (25.02.2021)
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Journal Article
Synthesis of Isotopically Labeled Anti-HIV Nucleoside Islatravir through a One-Pot Biocatalytic Cascade Reaction
Ren, Sumei, Huffman, Mark A, Whittaker, Aaron M, Yang, Hao, Nawrat, Christopher C, Waterhouse, David J, Maloney, Kevin M, Strotman, Neil A
Published in Organic process research & development (19.03.2021)
Published in Organic process research & development (19.03.2021)
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Journal Article
Five‐Step Enantioselective Synthesis of Islatravir via Asymmetric Ketone Alkynylation and an Ozonolysis Cascade
Patel, Niki R., Huffman, Mark A., Wang, Xiao, Ding, Bangwei, McLaughlin, Mark, Newman, Justin A., Andreani, Teresa, Maloney, Kevin M., Johnson, Heather C., Whittaker, Aaron M.
Published in Chemistry : a European journal (06.11.2020)
Published in Chemistry : a European journal (06.11.2020)
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