An Interbacterial NAD(P)+ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells
Whitney, John C., Quentin, Dennis, Sawai, Shin, LeRoux, Michele, Harding, Brittany N., Ledvina, Hannah E., Tran, Bao Q., Robinson, Howard, Goo, Young Ah, Goodlett, David R., Raunser, Stefan, Mougous, Joseph D.
Published in Cell (22.10.2015)
Published in Cell (22.10.2015)
Get full text
Journal Article
An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp
Ahmad, Shehryar, Wang, Boyuan, Walker, Matthew D., Tran, Hiu-Ki R., Stogios, Peter J., Savchenko, Alexei, Grant, Robert A., McArthur, Andrew G., Laub, Michael T., Whitney, John C.
Published in Nature (London) (01.11.2019)
Published in Nature (London) (01.11.2019)
Get full text
Journal Article
Structure of a bacterial Rhs effector exported by the type VI secretion system
Günther, Patrick, Quentin, Dennis, Ahmad, Shehryar, Sachar, Kartik, Gatsogiannis, Christos, Whitney, John C, Raunser, Stefan
Published in PLoS pathogens (01.01.2022)
Published in PLoS pathogens (01.01.2022)
Get full text
Journal Article
A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism
Russell, Alistair B., Wexler, Aaron G., Harding, Brittany N., Whitney, John C., Bohn, Alan J., Goo, Young Ah, Tran, Bao Q., Barry, Natasha A., Zheng, Hongjin, Peterson, S. Brook, Chou, Seemay, Gonen, Tamir, Goodlett, David R., Goodman, Andrew L., Mougous, Joseph D.
Published in Cell host & microbe (13.08.2014)
Published in Cell host & microbe (13.08.2014)
Get full text
Journal Article
The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix
Colvin, Kelly M., Irie, Yasuhiko, Tart, Catherine S., Urbano, Rodolfo, Whitney, John C., Ryder, Cynthia, Howell, P. Lynne, Wozniak, Daniel J., Parsek, Matthew R.
Published in Environmental microbiology (01.08.2012)
Published in Environmental microbiology (01.08.2012)
Get full text
Journal Article
Human symbionts inject and neutralize antibacterial toxins to persist in the gut
Wexler, Aaron G., Bao, Yiqiao, Whitney, John C., Bobay, Louis-Marie, Xavier, Joao B., Schofield, Whitman B., Barry, Natasha A., Russell, Alistair B., Tran, Bao Q., Goo, Young Ah, Goodlett, David R., Ochman, Howard, Mougous, Joseph D., Goodman, Andrew L.
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
Get full text
Journal Article
The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology
Wood, Thomas E., Howard, Sophie A., Förster, Andreas, Nolan, Laura M., Manoli, Eleni, Bullen, Nathan P., Yau, Hamish C.L., Hachani, Abderrahman, Hayward, Richard D., Whitney, John C., Vollmer, Waldemar, Freemont, Paul S., Filloux, Alain
Published in Cell reports (Cambridge) (01.10.2019)
Published in Cell reports (Cambridge) (01.10.2019)
Get full text
Journal Article
A widespread accessory protein family diversifies the effector repertoire of the type VI secretion system spike
Colautti, Jake, Tan, Huagang, Bullen, Nathan P., Thang, Stephanie S., Hackenberger, Dirk, Doxey, Andrew C., Whitney, John C.
Published in Nature communications (21.11.2024)
Published in Nature communications (21.11.2024)
Get full text
Journal Article
A broadly distributed toxin family mediates contact-dependent antagonism between gram-positive bacteria
Whitney, John C, Peterson, S Brook, Kim, Jungyun, Pazos, Manuel, Verster, Adrian J, Radey, Matthew C, Kulasekara, Hemantha D, Ching, Mary Q, Bullen, Nathan P, Bryant, Diane, Goo, Young Ah, Surette, Michael G, Borenstein, Elhanan, Vollmer, Waldemar, Mougous, Joseph D
Published in eLife (11.07.2017)
Published in eLife (11.07.2017)
Get full text
Journal Article
An enterococcal phage protein inhibits type IV restriction enzymes involved in antiphage defense
Bullen, Nathan P., Johnson, Cydney N., Andersen, Shelby E., Arya, Garima, Marotta, Sonia R., Lee, Yan-Jiun, Weigele, Peter R., Whitney, John C., Duerkop, Breck A.
Published in Nature communications (13.08.2024)
Published in Nature communications (13.08.2024)
Get full text
Journal Article
Identification, Structure, and Function of a Novel Type VI Secretion Peptidoglycan Glycoside Hydrolase Effector-Immunity Pair
Whitney, John C., Chou, Seemay, Russell, Alistair B., Biboy, Jacob, Gardiner, Taylor E., Ferrin, Michael A., Brittnacher, Mitchell, Vollmer, Waldemar, Mougous, Joseph D.
Published in The Journal of biological chemistry (13.09.2013)
Published in The Journal of biological chemistry (13.09.2013)
Get full text
Journal Article
Emerging and divergent roles of pyrophosphorylated nucleotides in bacterial physiology and pathogenesis
Chau, N Y Elizabeth, Ahmad, Shehryar, Whitney, John C, Coombes, Brian K
Published in PLoS pathogens (01.05.2021)
Published in PLoS pathogens (01.05.2021)
Get full text
Journal Article
Mechanism of loading and translocation of type VI secretion system effector Tse6
Quentin, Dennis, Ahmad, Shehryar, Shanthamoorthy, Premy, Mougous, Joseph D., Whitney, John C., Raunser, Stefan
Published in Nature microbiology (01.10.2018)
Published in Nature microbiology (01.10.2018)
Get full text
Journal Article
Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane
González-Magaña, Amaia, Tascón, Igor, Altuna-Alvarez, Jon, Queralt-Martín, María, Colautti, Jake, Velázquez, Carmen, Zabala, Maialen, Rojas-Palomino, Jessica, Cárdenas, Marité, Alcaraz, Antonio, Whitney, John C., Ubarretxena-Belandia, Iban, Albesa-Jové, David
Published in Nature communications (28.11.2023)
Published in Nature communications (28.11.2023)
Get full text
Journal Article
Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System
Klein, Timothy A., Grebenc, Dirk W., Shah, Prakhar Y., McArthur, Owen D., Dickson, Brandon H., Surette, Michael G., Kim, Youngchang, Whitney, John C.
Published in mBio (26.10.2022)
Published in mBio (26.10.2022)
Get full text
Journal Article
Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa
Whitney, John C., Whitfield, Gregory B., Marmont, Lindsey S., Yip, Patrick, Neculai, A. Mirela, Lobsanov, Yuri D., Robinson, Howard, Ohman, Dennis E., Howell, P. Lynne
Published in The Journal of biological chemistry (15.05.2015)
Published in The Journal of biological chemistry (15.05.2015)
Get full text
Journal Article
Structural basis for effector transmembrane domain recognition by type VI secretion system chaperones
Ahmad, Shehryar, Tsang, Kara K, Sachar, Kartik, Quentin, Dennis, Tashin, Tahmid M, Bullen, Nathan P, Raunser, Stefan, McArthur, Andrew G, Prehna, Gerd, Whitney, John C
Published in eLife (15.12.2020)
Published in eLife (15.12.2020)
Get full text
Journal Article
Kin cell lysis is a danger signal that activates antibacterial pathways of Pseudomonas aeruginosa
LeRoux, Michele, Kirkpatrick, Robin L, Montauti, Elena I, Tran, Bao Q, Peterson, S Brook, Harding, Brittany N, Whitney, John C, Russell, Alistair B, Traxler, Beth, Goo, Young Ah, Goodlett, David R, Wiggins, Paul A, Mougous, Joseph D
Published in eLife (02.02.2015)
Published in eLife (02.02.2015)
Get full text
Journal Article