Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents
Asshoff, Malte, Petzer, Verena, Warr, Matthew R., Haschka, David, Tymoszuk, Piotr, Demetz, Egon, Seifert, Markus, Posch, Wilfried, Nairz, Manfred, Maciejewski, Pat, Fowles, Peter, Burns, Christopher J., Smith, Gregg, Wagner, Kay-Uwe, Weiss, Guenter, Whitney, J.Andrew, Theurl, Igor
Published in Blood (30.03.2017)
Published in Blood (30.03.2017)
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Disruption of E-Cadherin-Mediated Adhesion Induces a Functionally Distinct Pathway of Dendritic Cell Maturation
Jiang, Aimin, Bloom, Ona, Ono, Satoru, Cui, Weiguo, Unternaehrer, Juli, Jiang, Shan, Whitney, J. Andrew, Connolly, John, Banchereau, Jacques, Mellman, Ira
Published in Immunity (Cambridge, Mass.) (01.10.2007)
Published in Immunity (Cambridge, Mass.) (01.10.2007)
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Templated Ligand Assembly by Using G-Quadruplex DNA and Dynamic Covalent Chemistry
Whitney, Andrew M., Ladame, Sylvain, Balasubramanian, Shankar
Published in Angewandte Chemie (International ed.) (20.02.2004)
Published in Angewandte Chemie (International ed.) (20.02.2004)
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Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase
Currie, Kevin S, Kropf, Jeffrey E, Lee, Tony, Blomgren, Peter, Xu, Jianjun, Zhao, Zhongdong, Gallion, Steve, Whitney, J. Andrew, Maclin, Deborah, Lansdon, Eric B, Maciejewski, Patricia, Rossi, Ann Marie, Rong, Hong, Macaluso, Jennifer, Barbosa, James, Di Paolo, Julie A, Mitchell, Scott A
Published in Journal of medicinal chemistry (08.05.2014)
Published in Journal of medicinal chemistry (08.05.2014)
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Journal Article
Cytoplasmic coat proteins involved in endosome function
Andrew Whitney, J., Gomez, Marie, Sheff, David, Kreis, Thomas E., Mellman, Ira
Published in Cell (01.12.1995)
Published in Cell (01.12.1995)
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Journal Article
Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis
Reif, Karin, Currie, Kevin S, Di Paolo, Julie A, Huang, Tao, Balazs, Mercedesz, Barbosa, James, Barck, Kai H, Bravo, Brandon J, Carano, Richard A D, Darrow, James, Davies, Douglas R, DeForge, Laura E, Diehl, Lauri, Ferrando, Ronald, Gallion, Steven L, Giannetti, Anthony M, Gribling, Peter, Hurez, Vincent, Hymowitz, Sarah G, Jones, Randall, Kropf, Jeffrey E, Lee, Wyne P, Maciejewski, Patricia M, Mitchell, Scott A, Rong, Hong, Staker, Bart L, Whitney, J Andrew, Yeh, Sherry, Young, Wendy B, Yu, Christine, Zhang, Juan
Published in Nature chemical biology (01.01.2011)
Published in Nature chemical biology (01.01.2011)
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Journal Article
Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development
Zheng, Jim, Xin, Yan, Zhang, Jingyu, Subramanian, Raju, Murray, Bernard P, Whitney, J Andrew, Warr, Matthew R, Ling, John, Moorehead, Lisa, Kwan, Ellen, Hemenway, Jeffrey, Smith, Bill J, Silverman, Jeffrey A
Published in Drug metabolism and disposition (01.03.2018)
Published in Drug metabolism and disposition (01.03.2018)
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Interaction of 2,4-Diaminopyrimidine-Containing Drugs Including Fedratinib and Trimethoprim with Thiamine Transporters
Giacomini, Marilyn M, Hao, Jia, Liang, Xiaomin, Chandrasekhar, Jayaraman, Twelves, Jolyn, Whitney, J Andrew, Lepist, Eve-Irene, Ray, Adrian S
Published in Drug metabolism and disposition (01.01.2017)
Published in Drug metabolism and disposition (01.01.2017)
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Journal Article
Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials
Ellingson, Benjamin M, Bendszus, Martin, Boxerman, Jerrold, Barboriak, Daniel, Erickson, Bradley J, Smits, Marion, Nelson, Sarah J, Gerstner, Elizabeth, Alexander, Brian, Goldmacher, Gregory, Wick, Wolfgang, Vogelbaum, Michael, Weller, Michael, Galanis, Evanthia, Kalpathy-Cramer, Jayashree, Shankar, Lalitha, Jacobs, Paula, Pope, Whitney B, Yang, Dewen, Chung, Caroline, Knopp, Michael V, Cha, Soonme, van den Bent, Martin J, Chang, Susan, Yung, W K Al, Cloughesy, Timothy F, Wen, Patrick Y, Gilbert, Mark R
Published in Neuro-oncology (Charlottesville, Va.) (01.09.2015)
Published in Neuro-oncology (Charlottesville, Va.) (01.09.2015)
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Journal Article
Functional Dissociation of Paracellular Permeability and Transepithelial Electrical Resistance and Disruption of the Apical-Basolateral Intramembrane Diffusion Barrier by Expression of a Mutant Tight Junction Membrane Protein
Balda, Maria S., Whitney, J. Andrew, Flores, Catalina, González, Sirenia, Cereijido, Marcelino, Matter, Karl
Published in The Journal of cell biology (01.08.1996)
Published in The Journal of cell biology (01.08.1996)
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Journal Article
Localization of Lysobisphosphatidic Acid-Rich Membrane Domains in Late Endosomes
Kobayashi, Toshihide, Startchev, Konstantin, Whitney, Andrew J., Gruenberg, Jean
Published in Biological chemistry (01.03.2001)
Published in Biological chemistry (01.03.2001)
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