Dynamic changes in the microRNA expression profile reveal multiple regulatory mechanisms in the spinal nerve ligation model of neuropathic pain
von Schack, David, Agostino, Michael J, Murray, B Stuart, Li, Yizheng, Reddy, Padmalatha S, Chen, Jin, Choe, Sung E, Strassle, Brian W, Li, Christine, Bates, Brian, Zhang, Lynn, Hu, Huijuan, Kotnis, Smita, Bingham, Brendan, Liu, Wei, Whiteside, Garth T, Samad, Tarek A, Kennedy, Jeffrey D, Ajit, Seena K
Published in PloS one (14.03.2011)
Published in PloS one (14.03.2011)
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Journal Article
An industry perspective on the role and utility of animal models of pain in drug discovery
Whiteside, Garth T., Pomonis, James D., Kennedy, Jeffrey D.
Published in Neuroscience letters (17.12.2013)
Published in Neuroscience letters (17.12.2013)
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Journal Article
Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice
Gao, Ying, Vasilyev, Dmitry V, Goncalves, Maria Beatriz, Howell, Fiona V, Hobbs, Carl, Reisenberg, Melina, Shen, Ru, Zhang, Mei-Yi, Strassle, Brian W, Lu, Peimin, Mark, Lilly, Piesla, Michael J, Deng, Kangwen, Kouranova, Evguenia V, Ring, Robert H, Whiteside, Garth T, Bates, Brian, Walsh, Frank S, Williams, Gareth, Pangalos, Menelas N, Samad, Tarek A, Doherty, Patrick
Published in The Journal of neuroscience (10.02.2010)
Published in The Journal of neuroscience (10.02.2010)
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A randomized, double-blind, positive-controlled, 3-way cross-over human experimental pain study of a TRPV1 antagonist (V116517) in healthy volunteers and comparison with preclinical profile
Arendt-Nielsen, Lars, Harris, Steve, Whiteside, Garth T, Hummel, Michele, Knappenberger, Terri, O'Keefe, Sarah, Kapil, Ram, Kyle, Don
Published in Pain (Amsterdam) (01.09.2016)
Published in Pain (Amsterdam) (01.09.2016)
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Journal Article
The nociceptin/orphanin FQ receptor partial agonist sunobinop promotes non-REM sleep in rodents and patients with insomnia
Whiteside, Garth T, Kyle, Donald J, Kapil, Ram R, Cipriano, Alessandra, He, Ellie, Zhou, Mingyan, Shet, Manjunath S, Hummel, Michele, Knappenberger, Terri, Fukumura, Kazuya, Matsuo, Yoshiyuki, Uehira, Masahiro, Hiroyama, Shuichi, Takai, Nozomi, Willsie, Sandra K, Harris, Stephen C
Published in The Journal of clinical investigation (02.01.2024)
Published in The Journal of clinical investigation (02.01.2024)
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Journal Article
The nociceptin/orphanin FQ receptor partial agonist sunobinop promotes non-REM sleep in rodents and patients with insomnia
Whiteside, Garth T, Kyle, Donald J, Kapil, Ram P, Cipriano, Alessandra, He, Ellie, Zhou, Mingyan, Shet, Manjunath S, Hummel, Michele, Knappenberger, Terri, Fukumura, Kazuya, Matsuo, Yoshiyuki, Uehira, Masahiro, Hiroyama, Shuichi, Takai, Nozomi, Willsie, Sandra K, Harris, Stephen C
Published in The Journal of clinical investigation (01.01.2024)
Published in The Journal of clinical investigation (01.01.2024)
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Journal Article
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system
Chanda, Pranab K, Gao, Ying, Mark, Lilly, Btesh, Joan, Strassle, Brian W, Lu, Peimin, Piesla, Michael J, Zhang, Mei-Yi, Bingham, Brendan, Uveges, Albert, Kowal, Dianne, Garbe, David, Kouranova, Evguenia V, Ring, Robert H, Bates, Brian, Pangalos, Menelas N, Kennedy, Jeffrey D, Whiteside, Garth T, Samad, Tarek A
Published in Molecular pharmacology (01.12.2010)
Published in Molecular pharmacology (01.12.2010)
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Journal Article
Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure
Dimiou, Savvas, Lopes, Rui M., Kubajewska, Ilona, Mellor, Ryan D., Schlosser, Corinna S., Shet, Manjunath S., Huang, Hugh, Akcan, Ozgur, Whiteside, Garth T., Schätzlein, Andreas G., Uchegbu, Ijeoma F.
Published in International journal of pharmaceutics (25.04.2022)
Published in International journal of pharmaceutics (25.04.2022)
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Journal Article
Depression-like phenotype following chronic CB1 receptor antagonism
Beyer, Chad E, Dwyer, Jason M, Piesla, Michael J, Platt, Brian J, Shen, Ru, Rahman, Zia, Chan, Karen, Manners, Melissa T, Samad, Tarek A, Kennedy, Jeffrey D, Bingham, Brendan, Whiteside, Garth T
Published in Neurobiology of disease (01.08.2010)
Published in Neurobiology of disease (01.08.2010)
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Journal Article
Safety, Tolerability, and Pharmacokinetics of Single‐ and Multiple‐Ascending Doses of Sunobinop in Healthy Participants
Cipriano, Alessandra, Kapil, Ram P., Zhou, Mingyan, Shet, Manjunath S., Whiteside, Garth T., Willsie, Sandra K., Harris, Stephen C.
Published in Clinical pharmacology in drug development (01.07.2024)
Published in Clinical pharmacology in drug development (01.07.2024)
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Journal Article
Targeting CB2 receptors and the endocannabinoid system for the treatment of pain
Anand, Praveen, Whiteside, Garth, Fowler, Christopher J, Hohmann, Andrea G
Published in Brain Research Reviews (01.04.2009)
Published in Brain Research Reviews (01.04.2009)
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Journal Article
Conference Proceeding
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy
Valenzano, Kenneth J., Tafesse, Laykea, Lee, Gary, Harrison, James E., Boulet, Jamie M., Gottshall, Susan L., Mark, Lilly, Pearson, Michelle S., Miller, Wendy, Shan, Shen, Rabadi, Leyana, Rotshteyn, Yakov, Chaffer, Suzanne M., Turchin, Paul I., Elsemore, David A., Toth, Mathew, Koetzner, Lee, Whiteside, Garth T.
Published in Neuropharmacology (01.04.2005)
Published in Neuropharmacology (01.04.2005)
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Journal Article
Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models
Piesla, Michael J, Leventhal, Liza, Strassle, Brian W, Harrison, James E, Cummons, Terri A, Lu, Peimin, Whiteside, Garth T
Published in Brain research (12.10.2009)
Published in Brain research (12.10.2009)
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Journal Article
CNS penetration of small molecules following local inflammation, widespread systemic inflammation or direct injury to the nervous system
Lu, Peimin, Gonzales, Cathy, Chen, Yi, Adedoyin, Adedayo, Hummel, Michele, Kennedy, Jeffrey D., Whiteside, Garth T.
Published in Life sciences (1973) (09.09.2009)
Published in Life sciences (1973) (09.09.2009)
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Journal Article
Pharmacological characterisation of a rat model of incisional pain
Whiteside, Garth T, Harrison, James, Boulet, Jamie, Mark, Lilly, Pearson, Michelle, Gottshall, Susan, Walker, Katharine
Published in British journal of pharmacology (01.01.2004)
Published in British journal of pharmacology (01.01.2004)
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