Efficacy of an EGFR-Specific Peptide against EGFR-Dependent Cancer Cell Lines and Tumor Xenografts
Ahsan, Aarif, Ramanand, Susmita G, Bergin, Ingrid L, Zhao, Lilli, Whitehead, Christopher E, Rehemtulla, Alnawaz, Ray, Dipankar, Pratt, William B, Lawrence, Theodore S, Nyati, Mukesh K
Published in Neoplasia (New York, N.Y.) (01.02.2014)
Published in Neoplasia (New York, N.Y.) (01.02.2014)
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Journal Article
Deciphering the Complexity of MEK Mutations in the Clinic
Whitehead, Christopher E, Sebolt-Leopold, Judith S
Published in Cancer research (Chicago, Ill.) (01.10.2020)
Published in Cancer research (Chicago, Ill.) (01.10.2020)
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Journal Article
Loss of NF1 in Melanoma Confers Sensitivity to SYK Kinase Inhibition
Abecunas, Cara, Whitehead, Christopher E, Ziemke, Elizabeth K, Baumann, Douglas G, Frankowski-McGregor, Christy L, Sebolt-Leopold, Judith S, Fallahi-Sichani, Mohammad
Published in Cancer research (Chicago, Ill.) (18.01.2023)
Published in Cancer research (Chicago, Ill.) (18.01.2023)
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Journal Article
Targeting DNA Repair and Survival Signaling in Diffuse Intrinsic Pontine Gliomas to Prevent Tumor Recurrence
Sharma, Monika, Barravecchia, Ivana, Teis, Robert, Cruz, Jeanette, Mumby, Rachel, Ziemke, Elizabeth K, Espinoza, Carlos E, Krishnamoorthy, Varunkumar, Magnuson, Brian, Ljungman, Mats, Koschmann, Carl, Chandra, Joya, Whitehead, Christopher E, Sebolt-Leopold, Judith S, Galban, Stefanie
Published in Molecular cancer therapeutics (03.01.2024)
Published in Molecular cancer therapeutics (03.01.2024)
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Journal Article
Oncogenic Mutants of MEK1 : A Trilogy Unfolds
Maust, Joel D, Whitehead, Christopher E, Sebolt-Leopold, Judith S
Published in Cancer discovery (01.05.2018)
Published in Cancer discovery (01.05.2018)
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A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance
Whitehead, Christopher E, Ziemke, Elizabeth K, Frankowski-McGregor, Christy L, Mumby, Rachel A, Chung, June, Li, Jinju, Osher, Nathaniel, Coker, Oluwadara, Baladandayuthapani, Veerabhadran, Kopetz, Scott, Sebolt-Leopold, Judith S
Published in Nature cancer (01.08.2024)
Published in Nature cancer (01.08.2024)
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Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide
Rodrigueza, Wendi V., Woolliscroft, Michael J., Ebrahim, Abdul-Shukkur, Forgey, Robert, McGovren, Patrick J., Endert, Gerold, Wagner, Andreas, Holewa, Danielle, Aboukameel, Amro, Gill, Richard D., Bisgaier, Charles L., Messmann, Richard A., Whitehead, Christopher E., Izbicka, Elzbieta, Streeper, Robert, Wick, Michael C., Stiegler, Gabriela, Stein, C. A., Monsma, David, Webb, Craig, Sooch, Mina P., Panzner, Steffen, Mohammad, Ramzi, Goodwin, Neal C., Al-Katib, Ayad
Published in Cancer chemotherapy and pharmacology (01.07.2014)
Published in Cancer chemotherapy and pharmacology (01.07.2014)
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4-Anilino-5-carboxamido-2-pyridone Derivatives as Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase
Spicer, Julie A, Rewcastle, Gordon W, Kaufman, Michael D, Black, Shannon L, Plummer, Mark S, Denny, William A, Quin, John, Shahripour, Aurash B, Barrett, Stephen D, Whitehead, Christopher E, Milbank, Jared B. J, Ohren, Jeffrey F, Gowan, Richard C, Omer, Charles, Camp, Heidi S, Esmaeil, Nadia, Moore, Kelley, Sebolt-Leopold, Judith S, Pryzbranowski, Sally, Merriman, Ronald L, Ortwine, Daniel F, Warmus, Joseph S, Flamme, Cathlin M, Pavlovsky, Alexander G, Tecle, Haile
Published in Journal of medicinal chemistry (18.10.2007)
Published in Journal of medicinal chemistry (18.10.2007)
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Abstract 3089: Evaluation of highly potent and selective single-molecule dual EGFR/PI3K inhibitors in preclinical models of adult and pediatric high-grade glioma
Sun, Yusha Y., Bailey, Cavan P., Carter, Trever R., Whitehead, Christopher E., Sebolt-Leopold, Judith S., Chandra, Joya
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 5871: Efficacy and selectivity of novel dually targeted kinase inhibitors for therapy of adult and pediatric high-grade glioma
Carter, Trever R., Bailey, Cavan P., Sun, Yusha Y., Espejo, Alexsandra B., Whitehead, Christopher E., Leopold, Judith, Chandra, Joya
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 148: A dual and selective small molecule inhibitor of EGFR and PI3 kinase shows promising preclinical activity against KRAS and BRAF mutant colorectal tumors
Maust, Joel D., Ziemke, Elizabeth K., Frankowski-McGregor, Christy L., Ku, Jun Beom, Mumby, Rachel, Hardiman, Karin M., Whitehead, Christopher E., Sebolt-Leopold, Judith S.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 1230: MTX-531, a first-in-class pan-PI3K inhibitor spares hyperinsulinemia yielding durable tumor regressions and resilience to adaptive resistance
Whitehead, Christopher E., Ziemke, Elizabeth K., Frankowski-McGregor, Christy L., Mumby, Rachel A., Chung, June, Li, Jinju, Osher, Nathaniel, Coker, Oluwadara, Norris, Michelle, Kopetz, Scott, Baladandayuthapani, Veera, Hollingshead, Melinda, Verma, Sharad, Sebolt-Leopold, Judith S.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Efficacy of an EGFR-Specific Peptide against EGFR-Dependent Cancer Cell Lines and Tumor Xenografts12
Ahsan, Aarif, Ramanand, Susmita G, Bergin, Ingrid L, Zhao, Lilli, Whitehead, Christopher E, Rehemtulla, Alnawaz, Ray, Dipankar, Pratt, William B, Lawrence, Theodore S, Nyati, Mukesh K
Published in Neoplasia (New York, N.Y.) (01.02.2014)
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Published in Neoplasia (New York, N.Y.) (01.02.2014)
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