Engineering Galanin Analogues That Discriminate between GalR1 and GalR2 Receptor Subtypes and Exhibit Anticonvulsant Activity following Systemic Delivery
Robertson, Charles R, Scholl, Erika Adkins, Pruess, Timothy H, Green, Brad R, White, H. Steve, Bulaj, Grzegorz
Published in Journal of medicinal chemistry (25.02.2010)
Published in Journal of medicinal chemistry (25.02.2010)
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Topiramate modulation of β(1)- and β(3)-homomeric GABA(A) receptors
Simeone, Timothy A, Wilcox, Karen S, White, H Steve
Published in Pharmacological research (01.07.2011)
Published in Pharmacological research (01.07.2011)
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Design, Synthesis, and Characterization of High-Affinity, Systemically-Active Galanin Analogues with Potent Anticonvulsant Activities
Bulaj, Grzegorz, Green, Brad R, Lee, Hee-Kyoung, Robertson, Charles R, White, Karen, Zhang, Liuyin, Sochanska, Marianna, Flynn, Sean P, Scholl, Erika Adkins, Pruess, Timothy H, Smith, Misty D, White, H. Steve
Published in Journal of medicinal chemistry (25.12.2008)
Published in Journal of medicinal chemistry (25.12.2008)
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Comparative Anticonvulsant and Mechanistic Profile of the Established and Newer Antiepileptic Drugs
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Conference Proceeding
Novel, Broad-Spectrum Anticonvulsants Containing a Sulfamide Group: Pharmacological Properties of (S)‑N‑[(6-Chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112)
McComsey, David F, Smith-Swintosky, Virginia L, Parker, Michael H, Brenneman, Douglas E, Malatynska, Ewa, White, H. Steve, Klein, Brian D, Wilcox, Karen S, Milewski, Michael E, Herb, Mark, Finley, Michael F. A, Liu, Yi, Lubin, Mary Lou, Qin, Ning, Reitz, Allen B, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (27.11.2013)
Published in Journal of medicinal chemistry (27.11.2013)
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Stapling Mimics Noncovalent Interactions of γ-Carboxyglutamates in Conantokins, Peptidic Antagonists of N-Methyl-d-Aspartic Acid Receptors
Platt, Randall J., Han, Tiffany S., Green, Brad R., Smith, Misty D., Skalicky, Jack, Gruszczyński, Paweł, White, H. Steve, Olivera, Baldomero, Bulaj, Grzegorz, Gajewiak, Joanna
Published in The Journal of biological chemistry (08.06.2012)
Published in The Journal of biological chemistry (08.06.2012)
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A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties
Lee, Hee-Kyoung, Zhang, Liuyin, Smith, Misty D, Walewska, Aleksandra, Vellore, Nadeem A, Baron, Riccardo, McIntosh, J Michael, White, H Steve, Olivera, Baldomero M, Bulaj, Grzegorz
Published in Frontiers in pharmacology (10.02.2015)
Published in Frontiers in pharmacology (10.02.2015)
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The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission
Walls, Anne B, Flynn, Sean P, West, Peter J, Müller, Margit S, Bak, Lasse K, Bulaj, Grzegorz, Schousboe, Arne, White, H. Steve
Published in Epilepsy research (01.03.2016)
Published in Epilepsy research (01.03.2016)
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GABA transporters as drug targets for modulation of GABAergic activity
Schousboe, Arne, Sarup, Alan, Larsson, Orla M., White, H. Steve
Published in Biochemical pharmacology (15.10.2004)
Published in Biochemical pharmacology (15.10.2004)
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Conference Proceeding
Developing Novel Antiepileptic Drugs: Characterization of NAX 5055, a Systemically-Active Galanin Analog, in Epilepsy Models
White, H. Steve, Scholl, Erika A., Klein, Brian D., Flynn, Sean P., Pruess, Timothy H., Green, Brad R., Zhang, Liuyin, Bulaj, Grzegorz
Published in Neurotherapeutics (01.04.2009)
Published in Neurotherapeutics (01.04.2009)
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Structural Requirements for a Lipoamino Acid in Modulating the Anticonvulsant Activities of Systemically Active Galanin Analogues
Zhang, Liuyin, Robertson, Charles R, Green, Brad R, Pruess, Timothy H, White, H. Steve, Bulaj, Grzegorz
Published in Journal of medicinal chemistry (12.03.2009)
Published in Journal of medicinal chemistry (12.03.2009)
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Clinical Significance of Animal Seizure Models and Mechanism of Action Studies of Potential Antiepileptic Drugs
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Conference Proceeding
Conantokins Derived from the Asprella Clade Impart conRl-B, an N-Methyl d-Aspartate Receptor Antagonist with a Unique Selectivity Profile for NR2B Subunits
Gowd, Konkallu Hanumae, Han, Tiffany S, Twede, Vernon, Gajewiak, Joanna, Smith, Misty D, Watkins, Maren, Platt, Randall J, Toledo, Gabriela, White, H. Steve, Olivera, Baldomero M, Bulaj, Grzegorz
Published in Biochemistry (Easton) (12.06.2012)
Published in Biochemistry (Easton) (12.06.2012)
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Traumatic brain injury during development reduces minimal clonic seizure thresholds at maturity
Statler, Kimberly D, Swank, Seth, Abildskov, Tracy, Bigler, Erin D, White, H. Steve
Published in Epilepsy research (01.08.2008)
Published in Epilepsy research (01.08.2008)
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Incorporation of Monodisperse Oligoethyleneglycol Amino Acids into Anticonvulsant Analogues of Galanin and Neuropeptide Y Provides Peripherally Acting Analgesics
Zhang, Liuyin, Klein, Brian D, Metcalf, Cameron S, Smith, Misty D, McDougle, Daniel R, Lee, Hee-Kyoung, White, H. Steve, Bulaj, Grzegorz
Published in Molecular pharmaceutics (04.02.2013)
Published in Molecular pharmaceutics (04.02.2013)
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