Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
Richter, Melanie, Murtaza, Nadeem, Scharrenberg, Robin, White, Sean H., Johanns, Ole, Walker, Susan, Yuen, Ryan K. C., Schwanke, Birgit, Bedürftig, Bianca, Henis, Melad, Scharf, Sarah, Kraus, Vanessa, Dörk, Ronja, Hellmann, Jakob, Lindenmaier, Zsuzsa, Ellegood, Jacob, Hartung, Henrike, Kwan, Vickie, Sedlacik, Jan, Fiehler, Jens, Schweizer, Michaela, Lerch, Jason P., Hanganu-Opatz, Ileana L., Morellini, Fabio, Scherer, Stephen W., Singh, Karun K., Calderon de Anda, Froylan
Published in Molecular psychiatry (01.09.2019)
Published in Molecular psychiatry (01.09.2019)
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Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons
Deneault, Eric, White, Sean H., Rodrigues, Deivid C., Ross, P. Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L., Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Lionel, Anath C., Pasceri, Peter, Merico, Daniele, Yuen, Ryan K.C., Singh, Karun K., Ellis, James, Scherer, Stephen W.
Published in Stem cell reports (13.11.2018)
Published in Stem cell reports (13.11.2018)
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Journal Article
CNTN5 - /+ or EHMT2 - /+ human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks
Deneault, Eric, Faheem, Muhammad, White, Sean H, Rodrigues, Deivid C, Sun, Song, Wei, Wei, Piekna, Alina, Thompson, Tadeo, Howe, Jennifer L, Chalil, Leon, Kwan, Vickie, Walker, Susan, Pasceri, Peter, Roth, Frederick P, Yuen, Ryan Kc, Singh, Karun K, Ellis, James, Scherer, Stephen W
Published in eLife (12.02.2019)
Published in eLife (12.02.2019)
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Journal Article
Disruption of the autism-associated gene SCN2A alters synaptic development and neuronal signaling in patient iPSC-glutamatergic neurons
Brown, Chad O, Uy, Jarryll A, Murtaza, Nadeem, Rosa, Elyse, Alfonso, Alexandria, Dave, Biren M, Kilpatrick, Savannah, Cheng, Annie A, White, Sean H, Scherer, Stephen W, Singh, Karun K
Published in Frontiers in cellular neuroscience (16.01.2024)
Published in Frontiers in cellular neuroscience (16.01.2024)
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Journal Article
DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants
Kwan, Vickie, Meka, Durga Praveen, White, Sean H., Hung, Claudia L., Holzapfel, Nicholas T., Walker, Susan, Murtaza, Nadeem, Unda, Brianna K., Schwanke, Birgit, Yuen, Ryan K.C., Habing, Kendra, Milsom, Chloe, Hope, Kristin J., Truant, Ray, Scherer, Stephen W., Calderon de Anda, Froylan, Singh, Karun K.
Published in Cell reports (Cambridge) (08.11.2016)
Published in Cell reports (Cambridge) (08.11.2016)
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Journal Article
OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome
Uddin, Mohammed, Unda, Brianna K., Kwan, Vickie, Holzapfel, Nicholas T., White, Sean H., Chalil, Leon, Woodbury-Smith, Marc, Ho, Karen S., Harward, Erin, Murtaza, Nadeem, Dave, Biren, Pellecchia, Giovanna, D’Abate, Lia, Nalpathamkalam, Thomas, Lamoureux, Sylvia, Wei, John, Speevak, Marsha, Stavropoulos, James, Hope, Kristin J., Doble, Brad W., Nielsen, Jacob, Wassman, E. Robert, Scherer, Stephen W., Singh, Karun K.
Published in American journal of human genetics (01.02.2018)
Published in American journal of human genetics (01.02.2018)
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Journal Article
Nicotine inhibits potassium currents in Aplysia bag cell neurons
White, Sean H, Sturgeon, Raymond M, Magoski, Neil S
Published in Journal of neurophysiology (01.05.2016)
Published in Journal of neurophysiology (01.05.2016)
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A potentially novel nicotinic receptor in Aplysia neuroendocrine cells
White, Sean H, Carter, Christopher J, Magoski, Neil S
Published in Journal of neurophysiology (15.07.2014)
Published in Journal of neurophysiology (15.07.2014)
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Journal Article
Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons
Deneault, Eric, White, Sean H., Rodrigues, Deivid C., Ross, P. Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L., Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Lionel, Anath C., Pasceri, Peter, Merico, Daniele, Yuen, Ryan K.C., Singh, Karun K., Ellis, James, Scherer, Stephen W.
Published in Stem cell reports (12.02.2019)
Published in Stem cell reports (12.02.2019)
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Journal Article
CNTN5.sup.-.sup./+or EHMT2.sup.-.sup./+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks
Deneault, Eric, Faheem, Muhammad, White, Sean H, Rodrigues, Deivid C, Sun, Song, Wei, Wei, Piekna, Alina, Thompson, Tadeo, Howe, Jennifer L, Chalil, Leon, Kwan, Vickie, Walker, Susan, Pasceri, Peter, Roth, Frederick P, Yuen, Ryan KC, Singh, Karun K, Ellis, James, Scherer, Stephen W
Published in eLife (12.02.2019)
Published in eLife (12.02.2019)
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Journal Article
Disruption of the autism-associated gene SCN2A alters synaptic development and neuronal signaling in patient iPSC-glutamatergic neurons
Brown, Chad O, Uy, Jarryll, Murtaza, Nadeem, Rosa, Elyse, Afonso, Alexandria, Sansi Xing, Dave, Biren M, Kilpatrick, Savannah, Cheng, Annie A, White, Sean H, Howe, Jennifer, Scherer, Stephen W, Lu, Yu, Singh, Karun K
Published in bioRxiv (16.09.2021)
Published in bioRxiv (16.09.2021)
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CNTN5-/+ or EHMT2-/+ iPSC-Derived Neurons from Individuals with Autism Develop Hyperactive Neuronal Networks
Deneault, Eric, Faheem, Muhammad, White, Sean H, Rodrigues, Deivid C, Sun, Song, Wei, Wei, Piekna, Alina, Thompson, Tadeo, Howe, Jennifer L, Chalil, Leon, Kwan, Vickie, Walker, Susan, Pasceri, Peter, Roth, Frederick P, Ryan Kc Yuen, Singh, Karun K, Ellis, James, Scherer, Stephen W
Published in bioRxiv (14.07.2018)
Published in bioRxiv (14.07.2018)
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Paper
Complete Disruption of Autism-Susceptibility Genes by Gene-Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons
Deneault, Eric, White, Sean H, Rodrigues, Deivid C, Ross, Joel, Faheem, Muhammad, Zaslavsky, Kirill, Wang, Zhuozhi, Alexandrova, Roumiana, Pellecchia, Giovanna, Wei, Wei, Piekna, Alina, Kaur, Gaganjot, Howe, Jennifer L, Kwan, Vickie, Thiruvahindrapuram, Bhooma, Walker, Susan, Pasceri, Peter, Merico, Daniele, Ryan Kc Yuen, Singh, Karun K, Ellis, James, Scherer, Stephen W
Published in bioRxiv (11.06.2018)
Published in bioRxiv (11.06.2018)
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