Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile
Tsiang, Manuel, Jones, Gregg S, Goldsmith, Joshua, Mulato, Andrew, Hansen, Derek, Kan, Elaine, Tsai, Luong, Bam, Rujuta A, Stepan, George, Stray, Kirsten M, Niedziela-Majka, Anita, Yant, Stephen R, Yu, Helen, Kukolj, George, Cihlar, Tomas, Lazerwith, Scott E, White, Kirsten L, Jin, Haolun
Published in Antimicrobial agents and chemotherapy (01.12.2016)
Published in Antimicrobial agents and chemotherapy (01.12.2016)
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Switching to bictegravir/emtricitabine/tenofovir alafenamide maintained HIV-1 RNA suppression in participants with archived antiretroviral resistance including M184V/I
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Published in Journal of antimicrobial chemotherapy (01.12.2019)
Published in Journal of antimicrobial chemotherapy (01.12.2019)
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MC1R Variation in a New Mexico Population
White, Kirsten A M, Dailey, Yvonne T, Guest, Dolores D, Zielaskowski, Kate, Robers, Erika, Sussman, Andrew, Hunley, Keith, Hughes, Christopher R, Schwartz, Matthew R, Kaphingst, Kimberly A, Buller, David B, Hay, Jennifer L, Berwick, Marianne
Published in Cancer epidemiology, biomarkers & prevention (01.11.2019)
Published in Cancer epidemiology, biomarkers & prevention (01.11.2019)
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Resistance Analysis of Bictegravir-Emtricitabine-Tenofovir Alafenamide in HIV-1 Treatment-Naive Patients through 48 Weeks
Acosta, Rima K, Willkom, Madeleine, Martin, Ross, Chang, Silvia, Wei, Xuelian, Garner, William, Lutz, Justin, Majeed, Sophia, SenGupta, Devi, Martin, Hal, Quirk, Erin, White, Kirsten L
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Published in Antimicrobial agents and chemotherapy (01.05.2019)
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Lack of impact of pre-existing T97A HIV-1 integrase mutation on integrase strand transfer inhibitor resistance and treatment outcome
Abram, Michael E, Ram, Renee R, Margot, Nicolas A, Barnes, Tiffany L, White, Kirsten L, Callebaut, Christian, Miller, Michael D
Published in PloS one (17.02.2017)
Published in PloS one (17.02.2017)
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Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial
DeJesus, Edwin, Rockstroh, Jürgen K, MD, Henry, Keith, MD, Molina, Jean-Michel, MD, Gathe, Joseph, MD, Ramanathan, Srinivasan, PhD, Wei, Xuelian, PhD, Yale, Kitty, MSc, Szwarcberg, Javier, MD, White, Kirsten, Prof, Cheng, Andrew K, MD, Kearney, Brian P, Prof
Published in The Lancet (British edition) (30.06.2012)
Published in The Lancet (British edition) (30.06.2012)
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Brief Report: Bictegravir/Emtricitabine/Tenofovir Alafenamide Efficacy in Participants With Preexisting Primary Integrase Inhibitor Resistance Through 48 Weeks of Phase 3 Clinical Trials
D'Antoni, Michelle L, Andreatta, Kristen, Acosta, Rima, Martin, Hal, Chang, Silvia, Martin, Ross, White, Kirsten L
Published in Journal of acquired immune deficiency syndromes (1999) (01.04.2022)
Published in Journal of acquired immune deficiency syndromes (1999) (01.04.2022)
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Antiviral activity of HIV‐1 integrase strand‐transfer inhibitors against mutants with integrase resistance‐associated mutations and their frequency in treatment‐naïve individuals
Margot, Nicolas A., Ram, Renee R., White, Kirsten L., Abram, Michael E., Callebaut, Christian
Published in Journal of medical virology (01.12.2019)
Published in Journal of medical virology (01.12.2019)
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A randomized double-blind comparison of coformulated elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate versus efavirenz/emtricitabine/tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: analysis of week 96 results
Zolopa, Andrew, Sax, Paul E, DeJesus, Edwin, Mills, Anthony, Cohen, Calvin, Wohl, David, Gallant, Joel E, Liu, Hui C, Plummer, Andrew, White, Kirsten L, Cheng, Andrew K, Rhee, Martin S, Szwarcberg, Javier
Published in Journal of acquired immune deficiency syndromes (1999) (01.05.2013)
Published in Journal of acquired immune deficiency syndromes (1999) (01.05.2013)
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Lack of an association between clinical INSTI-related body weight gain and direct interference with MC4 receptor (MC4R), a key central regulator of body weight
McMahon, Carrie, Trevaskis, James L, Carter, Christoph, Holsapple, Kevin, White, Kirsten, Das, Moupali, Collins, Sean, Martin, Hal, Burns-Naas, Leigh Ann
Published in PloS one (28.02.2020)
Published in PloS one (28.02.2020)
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High efficacy of switching to bictegravir/emtricitabine/tenofovir alafenamide in people with suppressed HIV and preexisting M184V/I
Sax, Paul E, Andreatta, Kristen, Molina, Jean-Michel, Daar, Eric S, Hagins, Debbie, Acosta, Rima, D'Antoni, Michelle L, Chang, Silvia, Martin, Ross, Liu, Hui, Blair, Christiana, McNicholl, Ian, Gallant, Joel, Collins, Sean E, Martin, Hal, White, Kirsten L
Published in AIDS (London) (01.09.2022)
Published in AIDS (London) (01.09.2022)
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Susceptibility to HIV-1 integrase strand transfer inhibitors (INSTIs) in highly treatment-experienced patients who failed an INSTI-based regimen
Santoro, Maria M., Fornabaio, Chiara, Malena, Marina, Galli, Laura, Poli, Andrea, Menozzi, Marianna, Zazzi, Maurizio, White, Kirsten L., Castagna, Antonella
Published in International journal of antimicrobial agents (01.07.2020)
Published in International journal of antimicrobial agents (01.07.2020)
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Impact of Primary Elvitegravir Resistance-Associated Mutations in HIV-1 Integrase on Drug Susceptibility and Viral Replication Fitness
ABRAM, Michael E, HLUHANICH, Rebecca M, SVAROVSKAIA, Evguenia S, MCCOLL, Damian J, WHITE, Kirsten L, MILLER, Michael D, GOODMAN, Derrick D, ANDREATTA, Kristen N, MARGOT, Nicolas A, LINDA YE, NIEDZIELA-MAJKA, Anita, BARNES, Tiffany L, NOVIKOV, Nikolai, XIAOWU CHEN
Published in Antimicrobial Agents and Chemotherapy (01.06.2013)
Published in Antimicrobial Agents and Chemotherapy (01.06.2013)
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Switching to Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) From Dolutegravir (DTG)+F/TAF or DTG+F/Tenofovir Disoproxil Fumarate (TDF) in the Presence of Pre-existing NRTI Resistance
Acosta, Rima K, Willkom, Madeleine, Andreatta, Kristen, Liu, Hui, Martin, Ross, Parvangada, Aiyappa, Martin, Hal, Collins, Sean, White, Kirsten L
Published in Journal of acquired immune deficiency syndromes (1999) (01.11.2020)
Published in Journal of acquired immune deficiency syndromes (1999) (01.11.2020)
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Three-year study of pre-existing drug resistance substitutions and efficacy of bictegravir/emtricitabine/tenofovir alafenamide in HIV-1 treatment-naive participants
Acosta, Rima K, Chen, Grace Q, Chang, Silvia, Martin, Ross, Wang, Xinxin, Huang, Hailin, Brainard, Diana, Collins, Sean E, Martin, Hal, White, Kirsten L
Published in Journal of antimicrobial chemotherapy (15.07.2021)
Published in Journal of antimicrobial chemotherapy (15.07.2021)
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A randomized, double-blind comparison of single-tablet regimen elvitegravir/cobicistat/emtricitabine/tenofovir DF versus single-tablet regimen efavirenz/emtricitabine/tenofovir DF for initial treatment of HIV-1 infection: analysis of week 144 results
Wohl, David A, Cohen, Calvin, Gallant, Joel E, Mills, Anthony, Sax, Paul E, Dejesus, Edwin, Zolopa, Andrew, Liu, Hui C, Plummer, Andrew, White, Kirsten L, Cheng, Andrew K, Rhee, Martin S, Szwarcberg, Javier
Published in Journal of acquired immune deficiency syndromes (1999) (01.03.2014)
Published in Journal of acquired immune deficiency syndromes (1999) (01.03.2014)
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Simplification to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of ritonavir-boosted protease inhibitor with emtricitabine and tenofovir in adults with virologically suppressed HIV (STRATEGY-PI): 48 week results of a randomised, open-label, phase 3b, non-inferiority trial
Arribas, Jose R, Dr, Pialoux, Gilles, Prof, Gathe, Joseph, MD, Di Perri, Giovanni, Prof, Reynes, Jacques, Prof, Tebas, Pablo, MD, Nguyen, Thai, MD, Ebrahimi, Ramin, MS, White, Kirsten, PhD, Piontkowsky, David, MD
Published in The Lancet infectious diseases (01.07.2014)
Published in The Lancet infectious diseases (01.07.2014)
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HIV-2 antiviral potency and selection of drug resistance mutations by the integrase strand transfer inhibitor elvitegravir and NRTIs emtricitabine and tenofovir in vitro
Andreatta, Kristen, Miller, Michael D, White, Kirsten L
Published in Journal of acquired immune deficiency syndromes (1999) (01.04.2013)
Published in Journal of acquired immune deficiency syndromes (1999) (01.04.2013)
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Switching to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of non-nucleoside reverse transcriptase inhibitor with emtricitabine and tenofovir in virologically suppressed adults with HIV (STRATEGY-NNRTI): 48 week results of a randomised, open-label, phase 3b non-inferiority trial
Pozniak, Anton, Dr, Markowitz, Martin, Prof, Mills, Anthony, MD, Stellbrink, Hans-Juergen, MD, Antela, Antonio, MD, Domingo, Pere, Prof, Girard, Pierre-Marie, MD, Henry, Keith, Prof, Nguyen, Thai, MD, Piontkowsky, David, MD, Garner, Will, PhD, White, Kirsten, PhD, Guyer, Bill, PharmD
Published in The Lancet infectious diseases (01.07.2014)
Published in The Lancet infectious diseases (01.07.2014)
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