Developing oral chronotherapy for cortisol replacement in congenital adrenal hyperplasia
Whitaker, Martin J., Debono, Miguel, Ross, Richard J.
Published in Clinical endocrinology (Oxford) (01.10.2024)
Published in Clinical endocrinology (Oxford) (01.10.2024)
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An oral multiparticulate, modified-release, hydrocortisone replacement therapy that provides physiological cortisol exposure
Whitaker, Martin J., Debono, Miguel, Huatan, Hiep, Merke, Deborah P., Arlt, Wiebke, Ross, Richard J.
Published in Clinical endocrinology (Oxford) (01.04.2014)
Published in Clinical endocrinology (Oxford) (01.04.2014)
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Journal Article
Salivary Cortisone Reflects Cortisol Exposure Under Physiological Conditions and After Hydrocortisone
Debono, Miguel, Harrison, Robert F, Whitaker, Martin J, Eckland, David, Arlt, Wiebke, Keevil, Brian G, Ross, Richard J
Published in The journal of clinical endocrinology and metabolism (01.04.2016)
Published in The journal of clinical endocrinology and metabolism (01.04.2016)
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Biorelevant in vitro assessment of dissolution and compatibility properties of a novel paediatric hydrocortisone drug product following exposure of the drug product to child-appropriate administration fluids
Wollmer, Erik, Neal, Greg, Whitaker, Martin J., Margetson, Daniel, Klein, Sandra
Published in European journal of pharmaceutics and biopharmaceutics (01.12.2018)
Published in European journal of pharmaceutics and biopharmaceutics (01.12.2018)
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Journal Article
Absorption and tolerability of taste‐masked hydrocortisone granules in neonates, infants and children under 6 years of age with adrenal insufficiency
Neumann, Uta, Whitaker, Martin J., Wiegand, Susanna, Krude, Heiko, Porter, John, Davies, Madhu, Digweed, Dena, Voet, Bernard, Ross, Richard J., Blankenstein, Oliver
Published in Clinical endocrinology (Oxford) (01.01.2018)
Published in Clinical endocrinology (Oxford) (01.01.2018)
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Journal Article
A Prospective Study of Children Aged 0–8 Years with CAH and Adrenal Insufficiency Treated with Hydrocortisone Granules
Neumann, Uta, Braune, Katarina, Whitaker, Martin J, Wiegand, Susanna, Krude, Heiko, Porter, John, Digweed, Dena, Voet, Bernard, Ross, Richard J M, Blankenstein, Oliver
Published in The journal of clinical endocrinology and metabolism (08.03.2021)
Published in The journal of clinical endocrinology and metabolism (08.03.2021)
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Journal Article
Development and verification of an endogenous PBPK model to inform hydrocortisone replacement dosing in children and adults with cortisol deficiency
Bonner, Jennifer J, Burt, Howard, Johnson, Trevor N, Whitaker, Martin J, Porter, John, Ross, Richard J
Published in European journal of pharmaceutical sciences (01.10.2021)
Published in European journal of pharmaceutical sciences (01.10.2021)
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Journal Article
A Phase 2 Study of Chronocort, a Modified-Release Formulation of Hydrocortisone, in the Treatment of Adults With Classic Congenital Adrenal Hyperplasia
Mallappa, Ashwini, Sinaii, Ninet, Kumar, Parag, Whitaker, Martin J, Daley, Lori-Ann, Digweed, Dena, Eckland, David J. A, Van Ryzin, Carol, Nieman, Lynnette K, Arlt, Wiebke, Ross, Richard J, Merke, Deborah P
Published in The journal of clinical endocrinology and metabolism (01.03.2015)
Published in The journal of clinical endocrinology and metabolism (01.03.2015)
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A Biopredictive In Vitro Approach for Assessing Compatibility of a Novel Pediatric Hydrocortisone Drug Product within Common Pediatric Dosing Vehicles
Wollmer, Erik, Karkossa, Frank, Freerks, Lisa, Hetberg, Anna-Elena, Neal, Greg, Porter, John, Whitaker, Martin J., Margetson, Daniel, Klein, Sandra
Published in Pharmaceutical research (01.10.2020)
Published in Pharmaceutical research (01.10.2020)
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Journal Article
Exploring Dried Blood Spot Cortisol Concentrations as an Alternative for Monitoring Pediatric Adrenal Insufficiency Patients: A Model-Based Analysis
Stachanow, Viktoria, Neumann, Uta, Blankenstein, Oliver, Bindellini, Davide, Melin, Johanna, Ross, Richard, Whitaker, Martin J, Huisinga, Wilhelm, Michelet, Robin, Kloft, Charlotte
Published in Frontiers in pharmacology (17.03.2022)
Published in Frontiers in pharmacology (17.03.2022)
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Paediatric population pharmacokinetic modelling to assess hydrocortisone replacement dosing regimens in young children
Michelet, Robin, Melin, Johanna, Parra-Guillen, Zinnia P, Neumann, Uta, Whitaker, J Martin, Stachanow, Viktoria, Huisinga, Wilhelm, Porter, John, Blankenstein, Oliver, Ross, Richard J, Kloft, Charlotte
Published in European journal of endocrinology (01.10.2020)
Published in European journal of endocrinology (01.10.2020)
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Journal Article
Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal hyperplasia
Jenkins-Jones, Sara, Parviainen, Lotta, Porter, John, Withe, Mike, Whitaker, Martin J, Holden, Sarah E, Morgan, Christopher LI, Currie, Craig J, Ross, Richard J M
Published in European journal of endocrinology (01.04.2018)
Published in European journal of endocrinology (01.04.2018)
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Journal Article
Accuracy of hydrocortisone dose administration via nasogastric tube
Daniel, Eleni, Whitaker, Martin J., Keevil, Brian, Wales, Jerry, Ross, Richard J.
Published in Clinical endocrinology (Oxford) (01.01.2019)
Published in Clinical endocrinology (Oxford) (01.01.2019)
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Journal Article
Modified release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia
Jones, Christopher M, Mallappa, Ashwini, Reisch, Nicole, Nikolaou, Nikolaos, Krone, Nils, Hughes, Beverly A, O’Neil, Donna M, Whitaker, Martin J, Tomlinson, Jeremy W, Storbeck, Karl-Heinz, Merke, Deborah P, Ross, Richard J, Arlt, Wiebke
Published in The journal of clinical endocrinology and metabolism (01.06.2017)
Published in The journal of clinical endocrinology and metabolism (01.06.2017)
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Journal Article
Wild jackdaws can selectively adjust their social associations while preserving valuable long-term relationships
Kings, Michael, Arbon, Josh J., McIvor, Guillam E., Whitaker, Martin, Radford, Andrew N., Lerner, Jürgen, Thornton, Alex
Published in Nature communications (11.09.2023)
Published in Nature communications (11.09.2023)
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Journal Article
Salivary Cortisone to Estimate Cortisol Exposure and Sampling Frequency Required Based on Serum Cortisol Measurements
Harrison, Robert F, Debono, Miguel, Whitaker, Martin J, Keevil, Brian G, Newell-Price, John, Ross, Richard J
Published in The journal of clinical endocrinology and metabolism (01.03.2019)
Published in The journal of clinical endocrinology and metabolism (01.03.2019)
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Journal Article
Applications of supercritical CO2 in the fabrication of polymer systems for drug delivery and tissue engineering
Davies, Owen R, Lewis, Andrew L, Whitaker, Martin J, Tai, Hongyun, Shakesheff, Kevin M, Howdle, Steven M
Published in Advanced drug delivery reviews (14.02.2008)
Published in Advanced drug delivery reviews (14.02.2008)
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