2-Nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the parp inhibitor 5-bromoisoquinolinone
Parveen, Ifat, Naughton, Declan P, Whish, William J.D, Threadgill, Michael D
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
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Synthesis of 3-Substituted Benzamides and 5-Substituted Isoquinolin-1(2H)-ones and Preliminary Evaluation as Inhibitors of Poly(ADP-ribose)polymerase (PARP)
Watson, Corrine Y., Whish, William J.D., Threadgill, Michael D.
Published in Bioorganic & medicinal chemistry (01.06.1998)
Published in Bioorganic & medicinal chemistry (01.06.1998)
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Synthesis of thiophenecarboxamides, thieno[3,4-c]pyridin-4(5H)-ones and thieno[3,4-d]pyrimidin-4(3H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP)
Shinkwin, A E, Whish, W J, Threadgill, M D
Published in Bioorganic & medicinal chemistry (01.02.1999)
Published in Bioorganic & medicinal chemistry (01.02.1999)
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The kinetics of affinity-mediated cell-surface attachment
Ming, Fang, Eisenthal, Robert, Whish, William J.D., Hubble, John
Published in Enzyme and microbial technology (01.02.2000)
Published in Enzyme and microbial technology (01.02.2000)
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5-nitrofuran-2-ylmethyl group as a potential bioreductively activated pro-drug system
Berry, JM, Watson, CY, Whish, WJD, Threadgill, MD
Published in Journal of the Chemical Society, Perkin Transactions 1 (21.04.1997)
Published in Journal of the Chemical Society, Perkin Transactions 1 (21.04.1997)
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The modification of nuclear proteins by ADP-ribosylation [Mouse liver and brain]
RICKWOOD, David, MacGILLIVRAY, Alexander J., WHISH, William J. D.
Published in European journal of biochemistry (01.01.1977)
Published in European journal of biochemistry (01.01.1977)
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