Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy
Martin, Nikolas T, Crupi, Mathieu J F, Taha, Zaid, Poutou, Joanna, Whelan, Jack T, Vallati, Sydney, Petryk, Julia, Marius, Ricardo, Austin, Bradley, Azad, Taha, Boulanger, Mason, Burgess, Tamara, Sanders, Ilson, Victoor, Camille, Dickinson, Bryan C, Diallo, Jean-Simon, Ilkow, Carolina S, Bell, John C
Published in Pharmaceuticals (Basel, Switzerland) (07.05.2023)
Published in Pharmaceuticals (Basel, Switzerland) (07.05.2023)
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Journal Article
CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX
Whelan, Jack T, Singaravelu, Ragunath, Wang, Fuan, Pelin, Adrian, Tamming, Levi A, Pugliese, Giuseppe, Martin, Nikolas T, Crupi, Mathieu J F, Petryk, Julia, Austin, Bradley, He, Xiaohong, Marius, Ricardo, Duong, Jessie, Jones, Carter, Fekete, Emily E F, Alluqmani, Nouf, Chen, Andrew, Boulton, Stephen, Huh, Michael S, Tang, Matt Y, Taha, Zaid, Scut, Elena, Diallo, Jean-Simon, Azad, Taha, Lichty, Brian D, Ilkow, Carolina S, Bell, John C
Published in Frontiers in immunology (13.01.2023)
Published in Frontiers in immunology (13.01.2023)
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Journal Article
Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization
Azad, Taha, Singaravelu, Ragunath, Crupi, Mathieu J.F., Jamieson, Taylor, Dave, Jaahnavi, Brown, Emily E.F., Rezaei, Reza, Taha, Zaid, Boulton, Stephen, Martin, Nikolas T., Surendran, Abera, Poutou, Joanna, Ghahremani, Mina, Nouri, Kazem, Whelan, Jack T., Duong, Jessie, Tucker, Sarah, Diallo, Jean-Simon, Bell, John C., Ilkow, Carolina S.
Published in Membranes (Basel) (30.08.2020)
Published in Membranes (Basel) (30.08.2020)
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Journal Article
Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy
Taha, Zaid, Crupi, Mathieu Joseph François, Alluqmani, Nouf, MacKenzie, Duncan, Vallati, Sydney, Whelan, Jack Timothy, Fareez, Faiha, Alwithenani, Akram, Petryk, Julia, Chen, Andrew, Spinelli, Marcus Mathew, Ng, Kristy, Sobh, Judy, de Souza, Christiano Tanese, Bharadwa, Priya Rose, Lee, Timothy Kit Hin, Thomas, Dylan Anthony, Huang, Ben Zhen, Kassas, Omar, Poutou, Joanna, Gilchrist, Victoria Heather, Boulton, Stephen, Thomson, Max, Marius, Ricardo, Hooshyar, Mohsen, McComb, Scott, Arulanandam, Rozanne, Ilkow, Carolina Solange, Bell, John Cameron, Diallo, Jean-Simon
Published in Nature communications (23.08.2024)
Published in Nature communications (23.08.2024)
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Journal Article
Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection
Boulton, Stephen, Poutou, Joanna, Martin, Nikolas T., Azad, Taha, Singaravelu, Ragunath, Crupi, Mathieu J.F., Jamieson, Taylor, He, Xiaohong, Marius, Ricardo, Petryk, Julia, Tanese de Souza, Christiano, Austin, Bradley, Taha, Zaid, Whelan, Jack, Khan, Sarwat T., Pelin, Adrian, Rezaei, Reza, Surendran, Abera, Tucker, Sarah, Fekete, Emily E.F., Dave, Jaahnavi, Diallo, Jean-Simon, Auer, Rebecca, Angel, Jonathan B., Cameron, D. William, Cailhier, Jean-Francois, Lapointe, Réjean, Potts, Kyle, Mahoney, Douglas J., Bell, John C., Ilkow, Carolina S.
Published in Molecular therapy (04.05.2022)
Published in Molecular therapy (04.05.2022)
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Journal Article
RECOMBINANT POLYPEPTIDES FOR PROGRAMMING EXTRACELLULAR VESICLES
BELL, John, Cameron, ILKOW, Carolina, Solange, BOULTON, Stephen, Donald, SINGARAVELU, Ragunath, MOHAMMADIAZAD, Mohammadtaha, CRUPI, Mathieu, François, Joseph, WHELAN, Jack, Timothy, DUONG, Jessie, Nhan, WANG, Fuan, PAUMIER, Yoanna, Poutou, ATHERTON, Matthew, John, LICHTY, Brian, Dennis
Year of Publication 13.03.2024
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Year of Publication 13.03.2024
Patent
RECOMBINANT POLYPEPTIDES FOR PROGRAMMING EXTRACELLULAR VESICLES
BELL, John Cameron, PAUMIER, Yoanna Poutou, DUONG, Jessie Nhan, SINGARAVELU, Ragunath, MOHAMMADIAZAD, Mohammadtaha, ATHERTON, Matthew John, LICHTY, Brian Dennis, WANG, Fuan, ILKOW, Carlolina Solange, WHELAN, Jack Timothy, BOULTON, Stephen Donald, CRUPI, Mathieu François Joseph
Year of Publication 29.06.2023
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Year of Publication 29.06.2023
Patent
RECOMBINANT POLYPEPTIDES FOR PROGRAMMING EXTRACELLULAR VESICLES
BELL, John, Cameron, ILKOW, Carolina, Solange, BOULTON, Stephen, Donald, SINGARAVELU, Ragunath, MOHAMMADIAZAD, Mohammadtaha, CRUPI, Mathieu, François, Joseph, WHELAN, Jack, Timothy, DUONG, Jessie, Nhan, WANG, Fuan, PAUMIER, Yoanna, Poutou, ATHERTON, Matthew, John, LICHTY, Brian, Dennis
Year of Publication 05.10.2022
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Year of Publication 05.10.2022
Patent
Recombinant polypeptides for programming extracellular vesicles
BELL, John Cameron, PAUMIER, Yoanna Poutou, DUONG, Jessie Nhan, SINGARAVELU, Ragunath, MOHAMMADIAZAD, Mohammadtaha, ATHERTON, Matthew John, ILKOW, Carolina Solange, LICHTY, Brian Dennis, WANG, Fuan, WHELAN, Jack Timothy, BOULTON, Stephen Donald, CRUPI, Mathieu François Joseph
Year of Publication 14.07.2022
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Year of Publication 14.07.2022
Patent
RECOMBINANT POLYPEPTIDES FOR PROGRAMMING EXTRACELLULAR VESICLES
BELL, John, DUONG, Jessie, PAUMIER, Yoanna, WHELAN, Jack, BOULTON, Stephen, SINGARAVELU, Ragunath, MOHAMMADIAZAD, Mohammadtaha, LICHTY, Brian, CRUPI, Mathieu, WANG, Fuan, ATHERTON, Matthew, ILKOW, Carolina
Year of Publication 03.06.2021
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Year of Publication 03.06.2021
Patent
RECOMBINANT POLYPEPTIDES FOR PROGRAMMING EXTRACELLULAR VESICLES
ILKOW, CAROLINA SOLANGE, SINGARAVELU, RAGUNATH, CRUPI, MATHIEU FRANCOIS JOSEPH, WHELAN, JACK TIMOTHY, ATHERTON, MATTHEW JOHN, BOULTON, STEPHEN DONALD, DUONG, JESSIE NHAN, WANG, FUAN, MOHAMMADIAZAD, MOHAMMADTAHA, BELL, JOHN CAMERON, LICHTY, BRIAN DENNIS, PAUMIER, YOANNA POUTOU
Year of Publication 03.06.2021
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Year of Publication 03.06.2021
Patent
Jack Whelan: A health-care win for all parties in Mass
Whelan, Jack
Published in Sun (Plainfield, Ill. : Homer Township, Lockport, Lemont ed.) (08.07.2014)
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Published in Sun (Plainfield, Ill. : Homer Township, Lockport, Lemont ed.) (08.07.2014)
Newspaper Article
Recombinant polypeptides for programming extracellular vesicles
MOHAMMAD DIAZADEH, MOHAMMAD TAHA, POMMIER IOANA PUTU, KRUPI MATHIEU FRANCOIS JOSEPH, WHELAN JACK TIMOTHY, WANG FUAN, BOLTON, STEPHEN, DONALD, SINGLAVERU, RAGHUNATH, DUONG, JESSE, NIEN, BELL JOHN CAMERON, ATHERTON MATTHEW JOHN, IRKOV CAROLINA SOLANGE, LICHTY BRIAN DENNIS
Year of Publication 15.07.2022
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Year of Publication 15.07.2022
Patent