BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis
Evans, Jonathan D W, Girerd, Barbara, Montani, David, Wang, Xiao-Jian, Galiè, Nazzareno, Austin, Eric D, Elliott, Greg, Asano, Koichiro, Grünig, Ekkehard, Yan, Yi, Jing, Zhi-Cheng, Manes, Alessandra, Palazzini, Massimiliano, Wheeler, Lisa A, Nakayama, Ikue, Satoh, Toru, Eichstaedt, Christina, Hinderhofer, Katrin, Wolf, Matthias, Rosenzweig, Erika B, Chung, Wendy K, Soubrier, Florent, Simonneau, Gérald, Sitbon, Olivier, Gräf, Stefan, Kaptoge, Stephen, Di Angelantonio, Emanuele, Humbert, Marc, Morrell, Nicholas W
Published in The lancet respiratory medicine (01.02.2016)
Published in The lancet respiratory medicine (01.02.2016)
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Longitudinal Analysis Casts Doubt on the Presence of Genetic Anticipation in Heritable Pulmonary Arterial Hypertension
LARKIN, Emma K, NEWMAN, John H, AUSTIN, Eric D, HEMNES, Anna R, WHEELER, Lisa, ROBBINS, Ivan M, WEST, James D, PHILLIPS, John A, HAMID, Rizwan, LOYD, James E
Published in American journal of respiratory and critical care medicine (01.11.2012)
Published in American journal of respiratory and critical care medicine (01.11.2012)
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Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II–Associated Pulmonary Arterial Hypertension Through MicroRNA-29–Mediated Modulation of Cellular Metabolism
Chen, Xinping, Talati, Megha, Fessel, Joshua P, Hemnes, Anna R, Gladson, Santhi, French, Jaketa, Shay, Sheila, Trammell, Aaron, Phillips, John A, Hamid, Rizwan, Cogan, Joy D, Dawson, Elliott P, Womble, Kristie E, Hedges, Lora K, Martinez, Elizabeth G, Wheeler, Lisa A, Loyd, James E, Majka, Susan J, West, James, Austin, Eric D
Published in Circulation (New York, N.Y.) (05.01.2016)
Published in Circulation (New York, N.Y.) (05.01.2016)
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Truncating and missense BMPR2 mutations differentially affect the severity of heritable pulmonary arterial hypertension
Austin, Eric D, Phillips, John A, Cogan, Joy D, Hamid, Rizwan, Yu, Chang, Stanton, Krista C, Phillips, Charles A, Wheeler, Lisa A, Robbins, Ivan M, Newman, John H, Loyd, James E
Published in Respiratory research (28.09.2009)
Published in Respiratory research (28.09.2009)
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Elevation of plasma cell-free hemoglobin in pulmonary arterial hypertension
Brittain, Evan L, Janz, David R, Austin, Eric D, Bastarache, Julie A, Wheeler, Lisa A, Ware, Lorraine B, Hemnes, Anna R
Published in Chest (01.12.2014)
Published in Chest (01.12.2014)
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High Frequency of BMPR2 Exonic Deletions/Duplications in Familial Pulmonary Arterial Hypertension
Cogan, Joy D, Pauciulo, Michael W, Batchman, Amy P, Prince, Melissa A, Robbins, Ivan M, Hedges, Lora K, Stanton, Krista C, Wheeler, Lisa A, Phillips, John A., III, Loyd, James E, Nichols, William C
Published in American journal of respiratory and critical care medicine (01.09.2006)
Published in American journal of respiratory and critical care medicine (01.09.2006)
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Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension
West, James D, Austin, Eric D, Gaskill, Christa, Marriott, Shennea, Baskir, Rubin, Bilousova, Ganna, Jean, Jyh-Chang, Hemnes, Anna R, Menon, Swapna, Bloodworth, Nathaniel C, Fessel, Joshua P, Kropski, Johnathan A, Irwin, David, Ware, Lorraine B, Wheeler, Lisa, Hong, Charles C, Meyrick, Barbara, Loyd, James E, Bowman, Aaron B, Ess, Kevin C, Klemm, Dwight J, Young, Pampee P, Merryman, W David, Kotton, Darrell, Majka, Susan M
Published in American Journal of Physiology: Cell Physiology (01.09.2014)
Published in American Journal of Physiology: Cell Physiology (01.09.2014)
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Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension
Maloney, James P, Stearman, Robert S, Bull, Todd M, Calabrese, David W, Tripp-Addison, Megan L, Wick, Marilee J, Broeckel, Ulrich, Robbins, Ivan M, Wheeler, Lisa A, Cogan, Joy D, Loyd, James E
Published in American journal of physiology. Lung cellular and molecular physiology (15.03.2012)
Published in American journal of physiology. Lung cellular and molecular physiology (15.03.2012)
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Mutation in the Gene for Bone Morphogenetic Protein Receptor II as a Cause of Primary Pulmonary Hypertension in a Large Kindred
Newman, John H, Wheeler, Lisa, Lane, Kirk B, Loyd, Emily, Loyd, James E, Gaddipati, Radhika, Phillips, John A
Published in The New England journal of medicine (02.08.2001)
Published in The New England journal of medicine (02.08.2001)
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FHIT , a Novel Modifier Gene in Pulmonary Arterial Hypertension
Dannewitz Prosseda, Svenja, Tian, Xuefei, Kuramoto, Kazuya, Boehm, Mario, Sudheendra, Deepti, Miyagawa, Kazuya, Zhang, Fan, Solow-Cordero, David, Saldivar, Joshua C., Austin, Eric D., Loyd, James E., Wheeler, Lisa, Andruska, Adam, Donato, Michele, Wang, Lingli, Huebner, Kay, Metzger, Ross J., Khatri, Purvesh, Spiekerkoetter, Edda
Published in American journal of respiratory and critical care medicine (01.01.2019)
Published in American journal of respiratory and critical care medicine (01.01.2019)
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Journal Article
BMPR2 Haploinsufficiency as the Inherited Molecular Mechanism for Primary Pulmonary Hypertension
Machado, Rajiv D, Pauciulo, Michael W., Thomson, Jennifer R., Lane, Kirk B., Morgan, Neil V., Wheeler, Lisa, Phillips III, John A., Newman, John, Williams, Denise, Galiè, Nazzareno, Manes, Alessandra, McNeil, Keith, Yacoub, Magdi, Mikhail, Ghada, Rogers, Paula, Corris, Paul, Humbert, Marc, Donnai, Dian, Martensson, Gunnar, Tranebjaerg, Lisbeth, Loyd, James E., Trembath, Richard C., Nichols, William C.
Published in American journal of human genetics (01.01.2001)
Published in American journal of human genetics (01.01.2001)
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Conference Proceeding
Prostanoids But Not Oral Therapies Improve Right Ventricular Function in Pulmonary Arterial Hypertension
Brittain, Evan L., MD, Pugh, Meredith E., MD, MSCI, Wheeler, Lisa A., BS, Robbins, Ivan M., MD, Loyd, James E., MD, Newman, John H., MD, Austin, Eric D., MD, MSCI, Hemnes, Anna R., MD
Published in JACC. Heart failure (01.08.2013)
Published in JACC. Heart failure (01.08.2013)
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Journal Article
Synergistic heterozygosity for TGFβ1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension
Phillips, John A., Poling, Justin S., Phillips, Charles A., Stanton, Krista C., Austin, Eric D., Cogan, Joy D., Wheeler, Lisa, Yu, Chang, Newman, John H., Dietz, Harry C., Loyd, James E.
Published in Genetics in medicine (01.05.2008)
Published in Genetics in medicine (01.05.2008)
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Journal Article
Tenascin-C is induced by mutated BMP type II receptors in familial forms of pulmonary arterial hypertension
Ihida-Stansbury, Kaori, McKean, David M, Lane, Kirk B, Loyd, James E, Wheeler, Lisa A, Morrell, Nicholas W, Jones, Peter Lloyd
Published in American journal of physiology. Lung cellular and molecular physiology (01.10.2006)
Published in American journal of physiology. Lung cellular and molecular physiology (01.10.2006)
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Journal Article
Pulmonary Veno-occlusive Disease Caused by an Inherited Mutation in Bone Morphogenetic Protein Receptor II
Runo, James R, Vnencak-Jones, Cindy L, Prince, Melissa, Loyd, James E, Wheeler, Lisa, Robbins, Ivan M, Lane, Kirk B, Newman, John H, Johnson, Joyce, Nichols, William C, Phillips, John A., III
Published in American journal of respiratory and critical care medicine (15.03.2003)
Published in American journal of respiratory and critical care medicine (15.03.2003)
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Journal Article
Serotonin Transporter Polymorphisms in Familial and Idiopathic Pulmonary Arterial Hypertension
Willers, Elisabeth D, Newman, John H, Loyd, James E, Robbins, Ivan M, Wheeler, Lisa A, Prince, Melissa A, Stanton, Krista C, Cogan, Joy A, Runo, James R, Byrne, Daniel, Humbert, Marc, Simonneau, Gerald, Sztrymf, Benjamin, Morse, Jane A, Knowles, James A, Roberts, Kari E, McElroy, Jude J, Barst, Robyn J, Phillips, John A., III
Published in American journal of respiratory and critical care medicine (01.04.2006)
Published in American journal of respiratory and critical care medicine (01.04.2006)
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Journal Article
Gross BMPR2 gene rearrangements constitute a new cause for primary pulmonary hypertension
Cogan, Joy D., Vnencak-Jones, Cindy L., Phillips, John A., Lane, Kirk B., Wheeler, Lisa A., Robbins, Ivan M., Garrison, Gladys, Hedges, Lora K., Loyd, James E.
Published in Genetics in medicine (01.03.2005)
Published in Genetics in medicine (01.03.2005)
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Journal Article
Shorter survival in familial versus idiopathic pulmonary arterial hypertension is associated with hemodynamic markers of impaired right ventricular function
Brittain, Evan L., Pugh, Meredith E., Wheeler, Lisa A., Robbins, Ivan M., Loyd, James E., Newman, John H., Larkin, Emma K., Austin, Eric D., Hemnes, Anna R.
Published in Pulmonary circulation (01.09.2013)
Published in Pulmonary circulation (01.09.2013)
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Journal Article
HERITABLE PULMONARY ARTERIAL HYPERTENSION IS ASSOCIATED WITH WORSE PULMONARY CAPACITANCE AND RIGHT VENTRICULAR STROKE WORK INDEX COMPARED TO IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION
Brittain, Evan L, Pugh, Meredith E, Wheeler, Lisa A, Wells, Quinn S, Robbins, Ivan M, Loyd, James E, Austin, Eric D, Hemnes, Anna R
Published in Journal of the American College of Cardiology (27.03.2012)
Published in Journal of the American College of Cardiology (27.03.2012)
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High-altitude pulmonary hypertension in cattle (brisket disease): Candidate genes and gene expression profiling of peripheral blood mononuclear cells
Newman, John H., Holt, Timothy N., Hedges, Lora K., Womack, Bethany, Memon, Shafia S., Willers, Elisabeth D., Wheeler, Lisa, Phillips, John A., Hamid, Rizwan
Published in Pulmonary circulation (01.10.2011)
Published in Pulmonary circulation (01.10.2011)
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