Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting
Ronson, George E, Starowicz, Katarzyna, Anthony, Elizabeth J, Piberger, Ann Liza, Clarke, Lucy C, Garvin, Alexander J, Beggs, Andrew D, Whalley, Celina M, Edmonds, Matthew J, Beesley, James F J, Morris, Joanna R
Published in Nature communications (29.11.2023)
Published in Nature communications (29.11.2023)
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Patient Derived Organoids Confirm That PI3K/AKT Signalling Is an Escape Pathway for Radioresistance and a Target for Therapy in Rectal Cancer
Wanigasooriya, Kasun, Barros-Silva, Joao D., Tee, Louise, El-asrag, Mohammed E., Stodolna, Agata, Pickles, Oliver J., Stockton, Joanne, Bryer, Claire, Hoare, Rachel, Whalley, Celina M., Tyler, Robert, Sillo, Toritseju, Yau, Christopher, Ismail, Tariq, Beggs, Andrew D.
Published in Frontiers in oncology (04.07.2022)
Published in Frontiers in oncology (04.07.2022)
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Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes
Goel, Anshita, Ward, Douglas G, Noyvert, Boris, Yu, Minghao, Gordon, Naheema S, Abbotts, Ben, Colbourne, John K, Kissane, Stephen, James, Nicholas D, Zeegers, Maurice P, Cheng, Kar Keung, Cazier, Jean-Baptiste, Whalley, Celina M, Beggs, Andrew D, Palles, Claire, Arnold, Roland, Bryan, Richard T
Published in Genome medicine (03.06.2022)
Published in Genome medicine (03.06.2022)
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Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning
Sirinukunwattana, Korsuk, Domingo, Enric, Richman, Susan D, Redmond, Keara L, Blake, Andrew, Verrill, Clare, Leedham, Simon J, Chatzipli, Aikaterini, Hardy, Claire, Whalley, Celina M, Wu, Chieh-hsi, Beggs, Andrew D, McDermott, Ultan, Dunne, Philip D, Meade, Angela, Walker, Steven M, Murray, Graeme I, Samuel, Leslie, Seymour, Matthew, Tomlinson, Ian, Quirke, Phil, Maughan, Timothy, Rittscher, Jens, Koelzer, Viktor H
Published in Gut (01.03.2021)
Published in Gut (01.03.2021)
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Ultrarapid detection of SARS-CoV-2 RNA using a reverse transcription–free exponential amplification reaction, RTF-EXPAR
Carter, Jake G., Orueta Iturbe, Lorea, Duprey, Jean-Louis H. A., Carter, Ian R., Southern, Craig D., Rana, Marium, Whalley, Celina M., Bosworth, Andrew, Beggs, Andrew D., Hicks, Matthew R., Tucker, James H. R., Dafforn, Timothy R.
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2021)
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Targeted deep sequencing of urothelial bladder cancers and associated urinary DNA: a 23‐gene panel with utility for non‐invasive diagnosis and risk stratification
Ward, Douglas G., Gordon, Naheema S., Boucher, Rebecca H., Pirrie, Sarah J., Baxter, Laura, Ott, Sascha, Silcock, Lee, Whalley, Celina M., Stockton, Joanne D., Beggs, Andrew D., Griffiths, Mike, Abbotts, Ben, Ijakipour, Hanieh, Latheef, Fathimath N., Robinson, Robert A., White, Andrew J., James, Nicholas D., Zeegers, Maurice P., Cheng, K. K., Bryan, Richard T.
Published in BJU international (01.09.2019)
Published in BJU international (01.09.2019)
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Whole Genome Methylation Analysis of Nondysplastic Barrett Esophagus that Progresses to Invasive Cancer
Dilworth, Mark P, Nieto, Tom, Stockton, Jo D, Whalley, Celina M, Tee, Louise, James, Jonathan D, Noble, Fergus, Underwood, Tim J, Hallissey, Michael T, Hejmadi, Rahul, Trudgill, Nigel, Tucker, Olga, Beggs, Andrew D
Published in Annals of surgery (01.03.2019)
Published in Annals of surgery (01.03.2019)
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MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids
Pickles, Oliver J, Wanigasooriya, Kasun, Ptasinska, Anetta, Patel, Akshay J, Robbins, Helen L, Bryer, Claire, Whalley, Celina M, Tee, Louise, Lal, Neeraj, Pinna, Claudia M A, Elzefzafy, Nahla, Taniere, Philippe, Beggs, Andrew D, Middleton, Gary M
Published in Cancer research communications (01.08.2023)
Published in Cancer research communications (01.08.2023)
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Abstract 2989: Colorectal cancer displays three patterns of tumor-specific MHC-II inducibility and dynamics, with implications for combining epigenetic therapy with immunotherapy
Pickles, Oliver J., Wanigasooriya, Kasun, Ptasinska, Anetta, Patel, Akshay J., Robbins, Helen L., Bryer, Claire, Whalley, Celina M., Tee, Louise, Lal, Neeraj, Pinna, Maria, Elzefzafy, Nahla, Taniere, Phillipe, Beggs, Andrew D., Middleton, Gary W.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Patient derived organoids reveal that PI3K/AKT signaling is an escape pathway for radioresistance and a target for therapy in rectal cancer
Wanigasooriya, Kasun, Barros-Silva, Joao D, Tee, Louise, Elasrag, Mohammed E, Stodolna, Agata, Pickles, Oliver, Stockton, Joanne D, Bryer, Clare, Hoare, Rachel, Whalley, Celina M, Tyler, Robert, Sillo, Toritseju, Yau, Christopher, Ismail, Tariq, Beggs, Andrew D
Published in bioRxiv (01.09.2021)
Published in bioRxiv (01.09.2021)
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Whole genome methylation analysis of non-dysplastic Barretts oesophagus that progresses to invasive cancer
Dilworth, Mark P, Nieto, Tom, Stockton, Joanne D, Whalley, Celina M, Tee, Louise, James, Jonathan D, Hallissey, Mike T, Hejmadi, Rahul, Trugdill, Nigel, Tucker, Olga, Beggs, Andrew D
Published in bioRxiv (06.03.2017)
Published in bioRxiv (06.03.2017)
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