Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease
Andersen, Jens V., Christensen, Sofie K., Westi, Emil W., Diaz-delCastillo, Marta, Tanila, Heikki, Schousboe, Arne, Aldana, Blanca I., Waagepetersen, Helle S.
Published in Neurobiology of disease (01.01.2021)
Published in Neurobiology of disease (01.01.2021)
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Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply
Andersen, Jens V, Westi, Emil W, Jakobsen, Emil, Urruticoechea, Nerea, Borges, Karin, Aldana, Blanca I
Published in Molecular brain (03.09.2021)
Published in Molecular brain (03.09.2021)
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Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease
Andersen, Jens V., Skotte, Niels H., Christensen, Sofie K., Polli, Filip S., Shabani, Mohammad, Markussen, Kia H., Haukedal, Henriette, Westi, Emil W., Diaz-delCastillo, Marta, Sun, Ramon C., Kohlmeier, Kristi A., Schousboe, Arne, Gentry, Matthew S., Tanila, Heikki, Freude, Kristine K., Aldana, Blanca I., Mann, Matthias, Waagepetersen, Helle S.
Published in Cell death & disease (16.10.2021)
Published in Cell death & disease (16.10.2021)
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Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus
Rimmele, Theresa S, Li, Shaomin, Andersen, Jens Velde, Westi, Emil W, Rotenberg, Alexander, Wang, Jianlin, Aldana, Blanca Irene, Selkoe, Dennis J, Aoki, Chiye J, Dulla, Chris G, Rosenberg, Paul Allen
Published in Frontiers in cellular neuroscience (29.12.2021)
Published in Frontiers in cellular neuroscience (29.12.2021)
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Comprehensive Analysis of the 5xFAD Mouse Model of Alzheimer's Disease Using dMRI, Immunohistochemistry, and Neuronal and Glial Functional Metabolic Mapping
Westi, Emil W, Molhemi, Saba, Hansen, Caroline Termøhlen, Skoven, Christian Stald, Knopper, Rasmus West, Ahmad, Dashne Amein, Rindshøj, Maja B, Ameen, Aishat O, Hansen, Brian, Kohlmeier, Kristi A, Aldana, Blanca I
Published in Biomolecules (Basel, Switzerland) (13.10.2024)
Published in Biomolecules (Basel, Switzerland) (13.10.2024)
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Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex
Andersen, Jens V., Westi, Emil W., Griem‐Krey, Nane, Skotte, Niels H., Schousboe, Arne, Aldana, Blanca I., Wellendorph, Petrine
Published in Journal of neurochemistry (01.05.2024)
Published in Journal of neurochemistry (01.05.2024)
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Metabolic preferences of astrocytes: Functional metabolic mapping reveals butyrate outcompetes acetate
Ameen, Aishat O, Nielsen, Sebastian W, Kjær, Martin W, Andersen, Jens V, Westi, Emil W, Freude, Kristine K, Aldana, Blanca I
Published in Journal of cerebral blood flow and metabolism (28.09.2024)
Published in Journal of cerebral blood flow and metabolism (28.09.2024)
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Extensive astrocyte metabolism of γ‐aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex
Andersen, Jens V., Jakobsen, Emil, Westi, Emil W., Lie, Maria E. K., Voss, Caroline M., Aldana, Blanca I., Schousboe, Arne, Wellendorph, Petrine, Bak, Lasse K., Pinborg, Lars H., Waagepetersen, Helle S.
Published in Glia (01.12.2020)
Published in Glia (01.12.2020)
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Deficient brain GABA metabolism leads to widespread impairments of astrocyte and oligodendrocyte function
Andersen, Jens V., Marian, Oana C., Qvist, Filippa L., Westi, Emil W., Aldana, Blanca I., Schousboe, Arne, Don, Anthony S., Skotte, Niels H., Wellendorph, Petrine
Published in Glia (01.10.2024)
Published in Glia (01.10.2024)
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Divergent Cellular Energetics, Glutamate Metabolism, and Mitochondrial Function Between Human and Mouse Cerebral Cortex
Westi, Emil W., Jakobsen, Emil, Voss, Caroline M., Bak, Lasse K., Pinborg, Lars H., Aldana, Blanca I., Andersen, Jens V.
Published in Molecular neurobiology (01.12.2022)
Published in Molecular neurobiology (01.12.2022)
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