The kinetic Direct Peptide Reactivity Assay (kDPRA): Intra- and inter-laboratory reproducibility in a seven-laboratory ring trial
Wareing, Britta, Kolle, Susanne N, Birk, Barbara, Alepee, Nathalie, Haupt, Tina, Kathawala, Rishil, Kern, Petra S, Nardelli, Laurent, Raabe, Hans, Rucki, Marian, Ryan, Cindy A, Verkaart, Sjoerd, Westerink, Walter M.A, Landsiedel, Robert, Natsch, Andreas
Published in ALTEX, alternatives to animal experimentation (01.01.2020)
Published in ALTEX, alternatives to animal experimentation (01.01.2020)
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Journal Article
The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development
Westerink, Walter M.A., Stevenson, Joe C.R., Horbach, G. Jean, Schoonen, Willem G.E.J.
Published in Mutation research (01.02.2010)
Published in Mutation research (01.02.2010)
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Journal Article
Evaluation of the Vitotox™ and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development
Westerink, Walter M.A., Stevenson, Joe C.R., Lauwers, Annick, Griffioen, Gerard, Horbach, G. Jean, Schoonen, Willem G.E.J.
Published in Mutation research (31.05.2009)
Published in Mutation research (31.05.2009)
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Journal Article
REACH alternative testing strategy for skin sensitization in practice: Fact or fiction?
Barentsen, Helma M., Jonis, Simon U., Pelgrom, Sylvia M.G.J., Rijk, Jeroen C.W., Westerink, Walter M.A., Paulussen, Jeannette J.C.
Published in Regulatory toxicology and pharmacology (01.08.2019)
Published in Regulatory toxicology and pharmacology (01.08.2019)
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Journal Article
Cytotoxic effects of 109 reference compounds on rat H4IIE and human HepG2 hepatocytes. III: Mechanistic assays on oxygen consumption with MitoXpress and NAD(P)H production with Alamar Blue
Schoonen, Willem G.E.J., Stevenson, Joe C.R., Westerink, Walter M.A., Horbach, G. Jean
Published in Toxicology in vitro (01.04.2012)
Published in Toxicology in vitro (01.04.2012)
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Journal Article
Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II mechanistic assays on NAD(P)H, ATP and DNA contents
Schoonen, Willem G E J, de Roos, Jeroen A D M, Westerink, Walter M A, Débiton, Eric
Published in Toxicology in vitro (01.06.2005)
Published in Toxicology in vitro (01.06.2005)
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Journal Article
Robust Array-Based Coregulator Binding Assay Predicting ERα-Agonist Potency and Generating Binding Profiles Reflecting Ligand Structure
Aarts, Jac M. M. J. G, Wang, Si, Houtman, René, van Beuningen, Rinie M. G. J, Westerink, Walter M. A, Van De Waart, Beppy J, Rietjens, Ivonne M. C. M, Bovee, Toine F. H
Published in Chemical research in toxicology (18.03.2013)
Published in Chemical research in toxicology (18.03.2013)
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Journal Article
Cytotoxic effects of 100 reference compounds on Hep G2 and HeLa cells and of 60 compounds on ECC-1 and CHO cells. I Mechanistic assays on ROS, glutathione depletion and calcein uptake
Schoonen, Willem G.E.J., Westerink, Walter M.A., de Roos, Jeroen A.D.M., Débiton, Eric
Published in Toxicology in vitro (01.06.2005)
Published in Toxicology in vitro (01.06.2005)
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Journal Article
CYP1A induction and species differences between human HepG2 and rat H4IIE cells
Westerink, Walter M.A., Stevenson, Joe C.R., Schoonen, Willem G.E.J.
Published in Toxicology letters (01.10.2007)
Published in Toxicology letters (01.10.2007)
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Journal Article
Genotoxicity and Carcinogenicity: Regulatory and Novel Test Methods
Westerink, Walter M.A, Stevenson, Joe C.R, Horbach, G. Jean, van de Water, Femke M, van de Waart, Beppy, G.E.J. Schoonen, Willem
Published in High‐Throughput Screening Methods in Toxicity Testing (13.02.2013)
Published in High‐Throughput Screening Methods in Toxicity Testing (13.02.2013)
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Book Chapter
174 Cytotoxic effects of 100 toxic compounds on HEP G2 and hela cells
Schoonen, Willem G.E.J., Westerink, Walter M.A., de Roos, Jeroen A.D.M., Débiton, Eric
Published in Toxicology letters (01.09.2003)
Published in Toxicology letters (01.09.2003)
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Journal Article