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Published in Cancer cell (09.02.2015)
Published in Cancer cell (09.02.2015)
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Kim, Ik Sun, Gao, Yang, Welte, Thomas, Wang, Hai, Liu, Jun, Janghorban, Mahnaz, Sheng, Kuanwei, Niu, Yichi, Goldstein, Amit, Zhao, Na, Bado, Igor, Lo, Hin-Ching, Toneff, Michael J., Nguyen, Tuan, Bu, Wen, Jiang, Weiyu, Arnold, James, Gu, Franklin, He, Jian, Jebakumar, Deborah, Walker, Kimberly, Li, Yi, Mo, Qianxing, Westbrook, Thomas F., Zong, Chenghang, Rao, Arundhati, Sreekumar, Arun, Rosen, Jeffrey M., Zhang, Xiang H.-F.
Published in Nature cell biology (01.09.2019)
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Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer
Dasgupta, Subhamoy, Rajapakshe, Kimal, Zhu, Bokai, Nikolai, Bryan C., Yi, Ping, Putluri, Nagireddy, Choi, Jong Min, Jung, Sung Y., Coarfa, Cristian, Westbrook, Thomas F., Zhang, Xiang H.-F., Foulds, Charles E., Tsai, Sophia Y., Tsai, Ming-Jer, O’Malley, Bert W.
Published in Nature (London) (01.04.2018)
Published in Nature (London) (01.04.2018)
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Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns
Sack, Laura Magill, Davoli, Teresa, Li, Mamie Z., Li, Yuyang, Xu, Qikai, Naxerova, Kamila, Wooten, Eric C., Bernardi, Ronald J., Martin, Timothy D., Chen, Ting, Leng, Yumei, Liang, Anthony C., Scorsone, Kathleen A., Westbrook, Thomas F., Wong, Kwok-Kin, Elledge, Stephen J.
Published in Cell (05.04.2018)
Published in Cell (05.04.2018)
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Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model
Lasagna-Reeves, Cristian A., de Haro, Maria, Hao, Shuang, Park, Jeehye, Rousseaux, Maxime W.C., Al-Ramahi, Ismael, Jafar-Nejad, Paymaan, Vilanova-Velez, Luis, See, Lauren, De Maio, Antonia, Nitschke, Larissa, Wu, Zhenyu, Troncoso, Juan C., Westbrook, Thomas F., Tang, Jianrong, Botas, Juan, Zoghbi, Huda Y.
Published in Neuron (Cambridge, Mass.) (19.10.2016)
Published in Neuron (Cambridge, Mass.) (19.10.2016)
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A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors
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Published in Cell reports (Cambridge) (09.06.2015)
Published in Cell reports (Cambridge) (09.06.2015)
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The spliceosome is a therapeutic vulnerability in MYC-driven cancer
Hsu, Tiffany Y.-T., Simon, Lukas M., Neill, Nicholas J., Marcotte, Richard, Sayad, Azin, Bland, Christopher S., Echeverria, Gloria V., Sun, Tingting, Kurley, Sarah J., Tyagi, Siddhartha, Karlin, Kristen L., Dominguez-Vidaña, Rocio, Hartman, Jessica D., Renwick, Alexander, Scorsone, Kathleen, Bernardi, Ronald J., Skinner, Samuel O., Jain, Antrix, Orellana, Mayra, Lagisetti, Chandraiah, Golding, Ido, Jung, Sung Y., Neilson, Joel R., Zhang, Xiang H.-F., Cooper, Thomas A., Webb, Thomas R., Neel, Benjamin G., Shaw, Chad A., Westbrook, Thomas F.
Published in Nature (London) (17.09.2015)
Published in Nature (London) (17.09.2015)
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A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene
Luo, Ji, Emanuele, Michael J., Li, Danan, Creighton, Chad J., Schlabach, Michael R., Westbrook, Thomas F., Wong, Kwok-Kin, Elledge, Stephen J.
Published in Cell (29.05.2009)
Published in Cell (29.05.2009)
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Control of Alveolar Differentiation by the Lineage Transcription Factors GATA6 and HOPX Inhibits Lung Adenocarcinoma Metastasis
Cheung, William K.C., Zhao, Minghui, Liu, Zongzhi, Stevens, Laura E., Cao, Paul D., Fang, Justin E., Westbrook, Thomas F., Nguyen, Don X.
Published in Cancer cell (10.06.2013)
Published in Cancer cell (10.06.2013)
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pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo
Meerbrey, Kristen L, Hu, Guang, Kessler, Jessica D, Roarty, Kevin, Li, Mamie Z, Fang, Justin E, Herschkowitz, Jason I, Burrows, Anna E, Ciccia, Alberto, Sun, Tingting, Schmitt, Earlene M, Bernardi, Ronald J, Fu, Xiaoyong, Bland, Christopher S, Cooper, Thomas A, Schiff, Rachel, Rosen, Jeffrey M, Westbrook, Thomas F, Elledge, Stephen J
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2011)
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A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis
Kessler, Jessica D., Kahle, Kristopher T., Sun, Tingting, Meerbrey, Kristen L., Schlabach, Michael R., Schmitt, Earlene M., Skinner, Samuel O., Xu, Qikai, Li, Mamie Z., Hartman, Zachary C., Rao, Mitchell, Yu, Peng, Dominguez-Vidana, Rocio, Liang, Anthony C., Solimini, Nicole L., Bernardi, Ronald J., Yu, Bing, Hsu, Tiffany, Golding, Ido, Luo, Ji, Osborne, C. Kent, Creighton, Chad J., Hilsenbeck, Susan G., Schiff, Rachel, Shaw, Chad A., Elledge, Stephen J., Westbrook, Thomas F.
Published in Science (American Association for the Advancement of Science) (20.01.2012)
Published in Science (American Association for the Advancement of Science) (20.01.2012)
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A Genetic Screen for Candidate Tumor Suppressors Identifies REST
Westbrook, Thomas F., Martin, Eric S., Schlabach, Michael R., Leng, Yumei, Liang, Anthony C., Feng, Bin, Zhao, Jean J., Roberts, Thomas M., Mandel, Gail, Hannon, Gregory J., DePinho, Ronald A., Chin, Lynda, Elledge, Stephen J.
Published in Cell (17.06.2005)
Published in Cell (17.06.2005)
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An Animal Model of MYC-Driven Medulloblastoma
Pei, Yanxin, Moore, Colin E., Wang, Jun, Tewari, Alok K., Eroshkin, Alexey, Cho, Yoon-Jae, Witt, Hendrik, Korshunov, Andrey, Read, Tracy-Ann, Sun, Julia L., Schmitt, Earlene M., Miller, C. Ryan, Buckley, Anne F., McLendon, Roger E., Westbrook, Thomas F., Northcott, Paul A., Taylor, Michael D., Pfister, Stefan M., Febbo, Phillip G., Wechsler-Reya, Robert J.
Published in Cancer cell (14.02.2012)
Published in Cancer cell (14.02.2012)
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Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer
Nair, Amritha, Chung, Hsiang-Ching, Sun, Tingting, Tyagi, Siddhartha, Dobrolecki, Lacey E, Dominguez-Vidana, Rocio, Kurley, Sarah J, Orellana, Mayra, Renwick, Alexander, Henke, David M, Katsonis, Panagiotis, Schmitt, Earlene, Chan, Doug W, Li, Hui, Mao, Sufeng, Petrovic, Ivana, Creighton, Chad J, Gutierrez, Carolina, Dubrulle, Julien, Stossi, Fabio, Tyner, Jeffrey W, Lichtarge, Olivier, Lin, Charles Y, Zhang, Bing, Scott, Kenneth L, Hilsenbeck, Susan G, Sun, Jinpeng, Yu, Xiao, Osborne, C Kent, Schiff, Rachel, Christensen, James G, Shields, David J, Rimawi, Mothaffar F, Ellis, Matthew J, Shaw, Chad A, Lewis, Michael T, Westbrook, Thomas F
Published in Nature medicine (01.04.2018)
Published in Nature medicine (01.04.2018)
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RAS–MAPK–MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1
Park, Jeehye, Al-Ramahi, Ismael, Tan, Qiumin, Mollema, Nissa, Diaz-Garcia, Javier R., Gallego-Flores, Tatiana, Lu, Hsiang-Chih, Lagalwar, Sarita, Duvick, Lisa, Kang, Hyojin, Lee, Yoontae, Jafar-Nejad, Paymaan, Sayegh, Layal S., Richman, Ronald, Liu, Xiuyun, Gao, Yan, Shaw, Chad A., Arthur, J. Simon C., Orr, Harry T., Westbrook, Thomas F., Botas, Juan, Zoghbi, Huda Y.
Published in Nature (London) (20.06.2013)
Published in Nature (London) (20.06.2013)
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TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau
Rousseaux, Maxime Wc, de Haro, Maria, Lasagna-Reeves, Cristian A, De Maio, Antonia, Park, Jeehye, Jafar-Nejad, Paymaan, Al-Ramahi, Ismael, Sharma, Ajay, See, Lauren, Lu, Nan, Vilanova-Velez, Luis, Klisch, Tiemo J, Westbrook, Thomas F, Troncoso, Juan C, Botas, Juan, Zoghbi, Huda Y
Published in eLife (25.10.2016)
Published in eLife (25.10.2016)
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Cancer Proliferation Gene Discovery Through Functional Genomics
Schlabach, Michael R, Luo, Ji, Solimini, Nicole L, Hu, Guang, Xu, Qikai, Li, Mamie Z, Zhao, Zhenming, Smogorzewska, Agata, Sowa, Mathew E, Ang, Xiaolu L, Westbrook, Thomas F, Liang, Anthony C, Chang, Kenneth, Hackett, Jennifer A, Harper, J. Wade, Hannon, Gregory J, Elledge, Stephen J
Published in Science (American Association for the Advancement of Science) (01.02.2008)
Published in Science (American Association for the Advancement of Science) (01.02.2008)
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Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression
Mowery, Cody T., Reyes, Jaime M., Cabal-Hierro, Lucia, Higby, Kelly J., Karlin, Kristen L., Wang, Jarey H., Kimmerling, Robert J., Cejas, Paloma, Lim, Klothilda, Li, Hubo, Furusawa, Takashi, Long, Henry W., Pellman, David, Chapuy, Bjoern, Bustin, Michael, Manalis, Scott R., Westbrook, Thomas F., Lin, Charles Y., Lane, Andrew A.
Published in Cell reports (Cambridge) (13.11.2018)
Published in Cell reports (Cambridge) (13.11.2018)
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Autologous skin-derived neural precursor cell therapy reverses canine Alzheimer dementia-like syndrome in a proof of concept veterinary trial
Valenzuela, Michael, Duncan, T, Abey, A, Johnson, A, Boulamatsis, C, Dalton, M. A, Jacobson, E, Brunel, L, Child, G, Simpson, D, Buckland, M, Lowe, A, Siette, J, Westbrook, F, McGreevy, P
Published in Stem cell research & therapy (17.06.2022)
Published in Stem cell research & therapy (17.06.2022)
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Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
Hirukawa, Alison, Singh, Salendra, Wang, Jarey, Rennhack, Jonathan P., Swiatnicki, Matthew, Sanguin-Gendreau, Virginie, Zuo, Dongmei, Daldoul, Kamilia, Lavoie, Cynthia, Park, Morag, Andrechek, Eran R., Westbrook, Thomas F., Harris, Lyndsay N., Varadan, Vinay, Smith, Harvey W., Muller, William J.
Published in Cell reports (Cambridge) (08.10.2019)
Published in Cell reports (Cambridge) (08.10.2019)
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