A Novel gp41-Binding Adnectin with Potent Anti-HIV Activity Is Highly Synergistic when Linked to a CD4-Binding Adnectin
Wensel, David, Sun, Yongnian, Davis, Jonathan, Li, Zhufang, Zhang, Sharon, McDonagh, Thomas, Fabrizio, David, Cockett, Mark, Krystal, Mark
Published in Journal of virology (15.07.2018)
Published in Journal of virology (15.07.2018)
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Preclinical Profile of the HIV-1 Maturation Inhibitor VH3739937
McAuliffe, Brian, Falk, Paul, Chen, Jie, Chen, Yan, Sit, Sing-Yuen, Swidorski, Jacob, Hartz, Richard A, Xu, Li, Venables, Brian, Sin, Ny, Meanwell, Nicholas A, Regueiro-Ren, Alicia, Wensel, David, Hanumegowda, Umesh, Krystal, Mark
Published in Viruses (24.09.2024)
Published in Viruses (24.09.2024)
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Complex Pharmacokinetics of a Humanized Antibody Against Human Amyloid Beta Peptide, Anti-Abeta Ab2, in Nonclinical Species
Vugmeyster, Yulia, Szklut, Pam, Wensel, David, Ross, John, Xu, Xin, Awwad, Michel, Gill, Davinder, Tchistiakov, Lioudmila, Warner, Garvin
Published in Pharmaceutical research (01.07.2011)
Published in Pharmaceutical research (01.07.2011)
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Journal Article
Developing Adnectins That Target SRC Co-Activator Binding to PXR: A Structural Approach toward Understanding Promiscuity of PXR
Khan, Javed A., Camac, Daniel M., Low, Simon, Tebben, Andrew J., Wensel, David L., Wright, Martin C., Su, Julie, Jenny, Victoria, Gupta, Ruchira Das, Ruzanov, Max, Russo, Katie A., Bell, Aneka, An, Yongmi, Bryson, James W., Gao, Mian, Gambhire, Pallavi, Baldwin, Eric T., Gardner, Daniel, Cavallaro, Cullen L., Duncia, John V., Hynes, John
Published in Journal of molecular biology (27.02.2015)
Published in Journal of molecular biology (27.02.2015)
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Journal Article
Structure and Mechanism of a Coreceptor for Infection by a Pathogenic Feline Retrovirus
Barnett, Anna L, Wensel, David L, Li, Weihua, Fass, Deborah, Cunningham, James M
Published in Journal of Virology (01.02.2003)
Published in Journal of Virology (01.02.2003)
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Journal Article
The sensitivity of HIV-1 gp120 polymorphs to inhibition by temsavir correlates to temsavir binding on-rate
Wensel, David, Gartland, Margaret, Beloor, Jagadish, Shetty, Kartika N., Wolf, Jana, Stewart, Eugene, Clark, Andrew, Tenorio, Allan, Krystal, Mark
Published in Antiviral research (01.09.2024)
Published in Antiviral research (01.09.2024)
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Journal Article
A Phase 1 randomized study of GSK3732394, an investigational long-acting biologic treatment regimen for HIV-1 infection
Krystal, Mark, Chabria, Shiven, Austin, Daren, Wolstenholme, Allen, Wensel, David, Lataillade, Max, Abberbock, Judah, Baker, Mark, Ackerman, Peter
Published in Antiviral therapy (01.10.2022)
Published in Antiviral therapy (01.10.2022)
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Journal Article
GSK3732394: a Multi-specific Inhibitor of HIV Entry
Wensel, David, Sun, Yongnian, Davis, Jonathan, Li, Zhufang, Zhang, Sharon, McDonagh, Thomas, Langley, David, Mitchell, Tracy, Tabruyn, Sebastien, Nef, Patrick, Cockett, Mark, Krystal, Mark
Published in Journal of virology (15.10.2019)
Published in Journal of virology (15.10.2019)
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Journal Article
Discovery and Characterization of a Novel CD4-Binding Adnectin with Potent Anti-HIV Activity
Wensel, David, Sun, Yongnian, Li, Zhufang, Zhang, Sharon, Picarillo, Caryn, McDonagh, Thomas, Fabrizio, David, Cockett, Mark, Krystal, Mark, Davis, Jonathan
Published in Antimicrobial agents and chemotherapy (01.08.2017)
Published in Antimicrobial agents and chemotherapy (01.08.2017)
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Journal Article
Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment
Wensel, David, Williams, Shawn, Dixon, David P., Ward, Paris, McCormick, Patti, Concha, Nestor, Stewart, Eugene, Hong, Xuan, Mazzucco, Charles, Pal, Shreya, Ding, Bo, Fellinger, Christoph, Krystal, Mark
Published in Journal of molecular biology (30.01.2022)
Published in Journal of molecular biology (30.01.2022)
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Journal Article
Utility of LC-MS Surrogate Peptide Methodology in the Development of a Combinectin, a Unique Anti-HIV Biologic Drug
Benitex, Yulia, Davis, Jonathan, Wensel, David L., Mitchell, Tracy S., Krystal, Mark R., Drexler, Dieter M.
Published in Journal of applied bioanalysis (10.07.2021)
Published in Journal of applied bioanalysis (10.07.2021)
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Journal Article
A Functional NaV1.7-NaVAb Chimera with a Reconstituted High-Affinity ProTx-II Binding Site
Rajamani, Ramkumar, Wu, Sophie, Rodrigo, Iyoncy, Gao, Mian, Low, Simon, Megson, Lisa, Wensel, David, Pieschl, Rick L, Post-Munson, Debra J, Watson, John, Langley, David R, Ahlijanian, Michael K, Bristow, Linda J, Herrington, James
Published in Molecular pharmacology (01.09.2017)
Published in Molecular pharmacology (01.09.2017)
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Journal Article
A Functional Na V 1.7-Na V Ab Chimera with a Reconstituted High-Affinity ProTx-II Binding Site
Rajamani, Ramkumar, Wu, Sophie, Rodrigo, Iyoncy, Gao, Mian, Low, Simon, Megson, Lisa, Wensel, David, Pieschl, Rick L, Post-Munson, Debra J, Watson, John, Langley, David R, Ahlijanian, Michael K, Bristow, Linda J, Herrington, James
Published in Molecular pharmacology (01.09.2017)
Published in Molecular pharmacology (01.09.2017)
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Journal Article
Developing Adnectins That Target SRC Co-Activator Binding to PXR: A Structural Approach toward Understanding Promiscuity of PXR
Khan, Javed A., Camac, Daniel M., Low, Simon, Tebben, Andrew J., Wensel, David L., Wright, Martin C., Su, Julie, Jenny, Victoria, Gupta, Ruchira Das, Ruzanov, Max, Russo, Katie A., Bell, Aneka, An, Yongmi, Bryson, James W., Gao, Mian, Gambhire, Pallavi, Baldwin, Eric T., Gardner, Daniel, Cavallaro, Cullen L., Duncia, John V., Hynes, Jr., John
Published in Journal of molecular biology (01.02.2015)
Published in Journal of molecular biology (01.02.2015)
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