β-Lactone formation during product release from a nonribosomal peptide synthetase
Schaffer, Jason E, Reck, Margaret R, Prasad, Neha K, Wencewicz, Timothy A
Published in Nature chemical biology (01.07.2017)
Published in Nature chemical biology (01.07.2017)
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Journal Article
Siderophore Synthetase DesD Catalyzes N‑to‑C Condensation in Desferrioxamine Biosynthesis
Yang, Jinping, Banas, Victoria S., Rivera, Gerry S. M., Wencewicz, Timothy A.
Published in ACS chemical biology (16.06.2023)
Published in ACS chemical biology (16.06.2023)
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Journal Article
Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes
Park, Jooyoung, Gasparrini, Andrew J, Reck, Margaret R, Symister, Chanez T, Elliott, Jennifer L, Vogel, Joseph P, Wencewicz, Timothy A, Dantas, Gautam, Tolia, Niraj H
Published in Nature chemical biology (01.07.2017)
Published in Nature chemical biology (01.07.2017)
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Journal Article
Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance
Gasparrini, Andrew J., Markley, Jana L., Kumar, Hirdesh, Wang, Bin, Fang, Luting, Irum, Sidra, Symister, Chanez T., Wallace, Meghan, Burnham, Carey-Ann D., Andleeb, Saadia, Tolia, Niraj H., Wencewicz, Timothy A., Dantas, Gautam
Published in Communications biology (15.05.2020)
Published in Communications biology (15.05.2020)
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Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling
Williford, Emily E., DeAngelo, Caitlin M., Blake, Kevin S., Kumar, Hirdesh, Lam, Kendrick K., Jones, Katherine V., Tolia, Niraj H., Dantas, Gautam, Wencewicz, Timothy A.
Published in Journal of medicinal chemistry (23.03.2023)
Published in Journal of medicinal chemistry (23.03.2023)
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Journal Article
Crystal Structure of the Siderophore Binding Protein BauB Bound to an Unusual 2:1 Complex Between Acinetobactin and Ferric Iron
Bailey, Daniel C, Bohac, Tabbetha J, Shapiro, Justin A, Giblin, Daryl E, Wencewicz, Timothy A, Gulick, Andrew M
Published in Biochemistry (Easton) (04.12.2018)
Published in Biochemistry (Easton) (04.12.2018)
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An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD
Yang, Jinping, Banas, Victoria S., Patel, Ketan D., Rivera, Gerry S.M., Mydy, Lisa S., Gulick, Andrew M., Wencewicz, Timothy A.
Published in The Journal of biological chemistry (01.08.2022)
Published in The Journal of biological chemistry (01.08.2022)
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