Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel
Liu, Fa, Park, Jung-Eun, Qian, Wen-Jian, Lim, Dan, Gräber, Martin, Berg, Thorsten, Yaffe, Michael B, Lee, Kyung S, Burke, Terrence R
Published in Nature chemical biology (17.07.2011)
Published in Nature chemical biology (17.07.2011)
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Peptoid-Peptide Hybrid Ligands Targeting the Polo Box Domain of Polo-Like Kinase 1
Liu, Fa, Park, Jung-Eun, Qian, Wen-Jian, Lim, Dan, Scharow, Andrej, Berg, Thorsten, Yaffe, Michael B., Lee, Kyung S., Burke Jr, Terrence R.
Published in Chembiochem : a European journal of chemical biology (18.06.2012)
Published in Chembiochem : a European journal of chemical biology (18.06.2012)
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Journal Article
Neighbor-directed histidine N (τ)-alkylation: A route to imidazolium-containing phosphopeptide macrocycles
Qian, Wen-Jian, Park, Jung-Eun, Grant, Robert, Lai, Christopher C., Kelley, James A., Yaffe, Michael B., Lee, Kyung S., Burke Jr, Terrence R.
Published in Biopolymers (01.11.2015)
Published in Biopolymers (01.11.2015)
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Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells
Qian, Wen-Jian, Park, Jung-Eun, Lim, Dan, Lai, Christopher C., Kelley, James A., Park, Suk-Youl, Lee, Ki Won, Yaffe, Michael B., Lee, Kyung S., Burke Jr, Terrence R.
Published in Biopolymers (01.11.2014)
Published in Biopolymers (01.11.2014)
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Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Using Oxime-Based Diversification
Liu, Fa, Park, Jung-Eun, Qian, Wen-Jian, Lim, Dan, Scharow, Andrej, Berg, Thorsten, Yaffe, Michael B, Lee, Kyung S, Burke, Terrence R
Published in ACS chemical biology (18.05.2012)
Published in ACS chemical biology (18.05.2012)
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Electrochemical Synthesis of 3‐Bromoimidazo[1,2‐a]pyridines Directly from 2‐Aminopyridines and alpha‐Bromoketones
Jian, Wen‐Qian, Wang, Hai‐Bin, Du, Ke‐Si, Zhong, Wei‐Qiang, Huang, Jing‐Mei
Published in ChemElectroChem (15.05.2019)
Published in ChemElectroChem (15.05.2019)
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Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding affinity for the polo box domain (PBD) of polo-like kinase 1 (Plk1)
Qian, Wen-Jian, Park, Jung-Eun, Lee, Kyung S., Burke, Terrence R.
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
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Synthesis of the cyclic nonapeptide of chlorofusin using a convergent [3+3+3]-fragment coupling strategy
Wang, Yan-Li, Qian, Wen-Jian, Wei, Wan-Guo, Zhang, Yue, Yao, Zhu-Jun
Published in Tetrahedron (08.05.2010)
Published in Tetrahedron (08.05.2010)
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Cover Picture: Peptoid-Peptide Hybrid Ligands Targeting the Polo Box Domain of Polo-Like Kinase 1 (ChemBioChem 9/2012)
Liu, Fa, Park, Jung-Eun, Qian, Wen-Jian, Lim, Dan, Scharow, Andrej, Berg, Thorsten, Yaffe, Michael B., Lee, Kyung S., Burke Jr, Terrence R.
Published in Chembiochem : a European journal of chemical biology (18.06.2012)
Published in Chembiochem : a European journal of chemical biology (18.06.2012)
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Bromoetherification-based strategy towards the spirocyclic chromophore of chlorofusin
Wei, Wan-Guo, Qian, Wen-Jian, Zhang, Yong-Xia, Yao, Zhu-Jun
Published in Tetrahedron letters (19.06.2006)
Published in Tetrahedron letters (19.06.2006)
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Direct shear behaviors of excavated clay reinforced with geocomposite drainage layer encapsulated in thin sand layers
Wang, Lin-Jie, Xu, Hui, Qian, Jian-Wen, Wang, Jin-Nan, Zhan, Liang-Tong
Published in Environmental science and pollution research international (01.06.2024)
Published in Environmental science and pollution research international (01.06.2024)
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Mitsunobu mischief: neighbor-directed histidine N(τ)-alkylation provides access to peptides containing selectively functionalized imidazolium heterocyclesElectronic supplementary information (ESI) available: Experimental details and NMR data for select compounds. See DOI: 10.1039/c5ob00171d
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