Discovery of a novel rhein-SAHA hybrid as a multi-targeted anti-glioblastoma drug
Chen, Jingkao, Luo, Bingling, Wen, Shijun, Pi, Rongbiao
Published in Investigational new drugs (01.06.2020)
Published in Investigational new drugs (01.06.2020)
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Design, Synthesis, and Evaluation of VHL-Based EZH2 Degraders to Enhance Therapeutic Activity against Lymphoma
Tu, Yalin, Sun, Yameng, Qiao, Shuang, Luo, Yao, Liu, Panpan, Jiang, Zhong-Xing, Hu, Yumin, Wang, Zifeng, Huang, Peng, Wen, Shijun
Published in Journal of medicinal chemistry (22.07.2021)
Published in Journal of medicinal chemistry (22.07.2021)
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Wild-type IDH2 protects nuclear DNA from oxidative damage and is a potential therapeutic target in colorectal cancer
Qiao, Shuang, Lu, Wenhua, Glorieux, Christophe, Li, Jiangjiang, Zeng, Peiting, Meng, Ning, Zhang, Huiqin, Wen, Shijun, Huang, Peng
Published in Oncogene (30.09.2021)
Published in Oncogene (30.09.2021)
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Mild Cu(I)-Catalyzed Cascade Reaction of Cyclic Diaryliodoniums, Sodium Azide, and Alkynes: Efficient Synthesis of Triazolophenanthridines
Liu, Zhenquan, Zhu, Daqian, Luo, Bingling, Zhang, Naiyuan, Liu, Qi, Hu, Yumin, Pi, Rongbiao, Huang, Peng, Wen, Shijun
Published in Organic letters (07.11.2014)
Published in Organic letters (07.11.2014)
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Wild-type IDH2 is a therapeutic target for triple-negative breast cancer
Li, Jiang-jiang, Yu, Tiantian, Zeng, Peiting, Tian, Jingyu, Liu, Panpan, Qiao, Shuang, Wen, Shijun, Hu, Yumin, Liu, Qiao, Lu, Wenhua, Zhang, Hui, Huang, Peng
Published in Nature communications (24.04.2024)
Published in Nature communications (24.04.2024)
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Reductive TCA cycle catalyzed by wild-type IDH2 promotes acute myeloid leukemia and is a metabolic vulnerability for potential targeted therapy
Zeng, Peiting, Lu, Wenhua, Tian, Jingyu, Qiao, Shuang, Li, Jiangjiang, Glorieux, Christophe, Wen, Shijun, Zhang, Hui, Li, Yiqing, Huang, Peng
Published in Journal of hematology and oncology (21.03.2022)
Published in Journal of hematology and oncology (21.03.2022)
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Heterocyclic iodoniums as versatile synthons to approach diversified polycyclic heteroarenes
Zhu, Daqian, Wu, Zhouming, Liang, Liyun, Sun, Yameng, Luo, Bingling, Huang, Peng, Wen, Shijun
Published in RSC advances (16.10.2019)
Published in RSC advances (16.10.2019)
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Developing Bi-Gold Compound BGC2a to Target Mitochondria for the Elimination of Cancer Cells
Cui, Qingbin, Ding, Wenwen, Liu, Panpan, Luo, Bingling, Yang, Jing, Lu, Wenhua, Hu, Yumin, Huang, Peng, Wen, Shijun
Published in International journal of molecular sciences (12.10.2022)
Published in International journal of molecular sciences (12.10.2022)
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The rheumatoid arthritis drug auranofin exerts potent anti-lymphoma effect by stimulating TXNRD-mediated ROS generation and inhibition of energy metabolism
Yang, Mengqi, Liu, Jiaxin, Li, Jianan, Wen, Shijun, Hu, Yumin, Lu, Wenhua, Liu, Jinyun, Huang, Peng, Liu, Panpan
Published in Redox biology (01.09.2024)
Published in Redox biology (01.09.2024)
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Three-Component Pd/Cu-Catalyzed Cascade Reactions of Cyclic Iodoniums, Alkynes, and Boronic Acids: An Approach to Methylidenefluorenes
Zhu, Daqian, Wu, Yongcheng, Wu, Baojian, Luo, Bingling, Ganesan, A., Wu, Fu-Hai, Pi, Rongbiao, Huang, Peng, Wen, Shijun
Published in Organic letters (02.05.2014)
Published in Organic letters (02.05.2014)
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Journal Article
Micro-RNA-155 is induced by K-Ras oncogenic signal and promotes ROS stress in pancreatic cancer
Wang, Peng, Zhu, Chao-feng, Ma, Ming-zhe, Chen, Gang, Song, Ming, Zeng, Zhao-lei, Lu, Wen-hua, Yang, Jing, Wen, Shijun, Chiao, Paul J, Hu, Yumin, Huang, Peng
Published in Oncotarget (28.08.2015)
Published in Oncotarget (28.08.2015)
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Journal Article
EZH2 mediated metabolic rewiring promotes tumor growth independently of histone methyltransferase activity in ovarian cancer
Chen, Jianfeng, Hong, Jing Han, Huang, Yulin, Liu, Shini, Yin, Jiaxin, Deng, Peng, Sun, Yichen, Yu, Zhaoliang, Zeng, Xian, Xiao, Rong, Chan, Jason Yongsheng, Guan, Peiyong, Wang, Yali, Wang, Peili, Liu, Lizhen, Wen, Shijun, Yu, Qiang, Ong, Choon Kiat, Teh, Bin-Tean, Xiong, Ying, Tan, Jing
Published in Molecular cancer (20.05.2023)
Published in Molecular cancer (20.05.2023)
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Application of Fragment Growing and Fragment Linking to the Discovery of Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase
Hung, Alvin W, Silvestre, H. Leonardo, Wen, Shijun, Ciulli, Alessio, Blundell, Tom L, Abell, Chris
Published in Angewandte Chemie (International ed.) (26.10.2009)
Published in Angewandte Chemie (International ed.) (26.10.2009)
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Relayed Regioselective Alkynylation/Olefination of Unsymmetrical Cyclic Diaryliodonium Species Catalyzed by Cu and Pd: Affording Fluorescent Cytotoxic Benzoxazoles
Zhu, Daqian, Liu, Panpan, Lu, Wenhua, Wang, Haiwen, Luo, Bingling, Hu, Yumin, Huang, Peng, Wen, Shijun
Published in Chemistry : a European journal (21.12.2015)
Published in Chemistry : a European journal (21.12.2015)
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Journal Article
Mitochondrial TXNRD3 confers drug resistance via redox-mediated mechanism and is a potential therapeutic target in vivo
Liu, Xiaoxia, Zhang, Yanyu, Lu, Wenhua, Han, Yi, Yang, Jing, Jiang, Weiye, You, Xin, Luo, Yao, Wen, Shijun, Hu, Yumin, Huang, Peng
Published in Redox biology (01.09.2020)
Published in Redox biology (01.09.2020)
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