The lingering mysteries of metastatic recurrence in breast cancer
Riggio, Alessandra I, Varley, Katherine E, Welm, Alana L
Published in British journal of cancer (05.01.2021)
Published in British journal of cancer (05.01.2021)
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Understanding the Bone in Cancer Metastasis
Fornetti, Jaime, Welm, Alana L, Stewart, Sheila A
Published in Journal of bone and mineral research (01.12.2018)
Published in Journal of bone and mineral research (01.12.2018)
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Plasma exosome microRNAs are indicative of breast cancer
Hannafon, Bethany N, Trigoso, Yvonne D, Calloway, Cameron L, Zhao, Y Daniel, Lum, David H, Welm, Alana L, Zhao, Zhizhuang J, Blick, Kenneth E, Dooley, William C, Ding, W Q
Published in Breast cancer research : BCR (08.09.2016)
Published in Breast cancer research : BCR (08.09.2016)
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A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds
Bruna, Alejandra, Rueda, Oscar M., Greenwood, Wendy, Batra, Ankita Sati, Callari, Maurizio, Batra, Rajbir Nath, Pogrebniak, Katherine, Sandoval, Jose, Cassidy, John W., Tufegdzic-Vidakovic, Ana, Sammut, Stephen-John, Jones, Linda, Provenzano, Elena, Baird, Richard, Eirew, Peter, Hadfield, James, Eldridge, Matthew, McLaren-Douglas, Anne, Barthorpe, Andrew, Lightfoot, Howard, O’Connor, Mark J., Gray, Joe, Cortes, Javier, Baselga, Jose, Marangoni, Elisabetta, Welm, Alana L., Aparicio, Samuel, Serra, Violeta, Garnett, Mathew J., Caldas, Carlos
Published in Cell (22.09.2016)
Published in Cell (22.09.2016)
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Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
Kinsey, Conan G, Camolotto, Soledad A, Boespflug, Amelie M, Guillen, Katrin P, Foth, Mona, Truong, Amanda, Schuman, Sophia S, Shea, Jill E, Seipp, Michael T, Yap, Jeffrey T, Burrell, Lance D, Lum, David H, Whisenant, Jonathan R, Gilcrease, 3rd, G Weldon, Cavalieri, Courtney C, Rehbein, Kaitrin M, Cutler, Stephanie L, Affolter, Kajsa E, Welm, Alana L, Welm, Bryan E, Scaife, Courtney L, Snyder, Eric L, McMahon, Martin
Published in Nature medicine (01.04.2019)
Published in Nature medicine (01.04.2019)
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Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance
Takahashi, Nobuaki, Chen, Hsing-Yu, Harris, Isaac S., Stover, Daniel G., Selfors, Laura M., Bronson, Roderick T., Deraedt, Thomas, Cichowski, Karen, Welm, Alana L., Mori, Yasuo, Mills, Gordon B., Brugge, Joan S.
Published in Cancer cell (11.06.2018)
Published in Cancer cell (11.06.2018)
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Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis
Tavora, Bernardo, Mederer, Tobias, Wessel, Kai J, Ruffing, Simon, Sadjadi, Mahan, Missmahl, Marc, Ostendorf, Benjamin N, Liu, Xuhang, Kim, Ji-Young, Olsen, Olav, Welm, Alana L, Goodarzi, Hani, Tavazoie, Sohail F
Published in Nature (London) (08.10.2020)
Published in Nature (London) (08.10.2020)
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
Woo, Xing Yi, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W, de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh, Chen, Li, Scherer, Sandra, Bailey, Matthew H, Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Xi, Yuanxin, Wang, Jing, Wickramasinghe, Jayamanna, Kossenkov, Andrew V, Rebecca, Vito W, Sun, Hua, Mashl, R Jay, Davies, Sherri R, Jeon, Ryan, Frech, Christian, Randjelovic, Jelena, Rosains, Jacqueline, Galimi, Francesco, Bertotti, Andrea, Lafferty, Adam, O'Farrell, Alice C, Modave, Elodie, Lambrechts, Diether, Ter Brugge, Petra, Serra, Violeta, Marangoni, Elisabetta, El Botty, Rania, Kim, Hyunsoo, Kim, Jong-Il, Yang, Han-Kwang, Lee, Charles, Dean, 2nd, Dennis A, Davis-Dusenbery, Brandi, Evrard, Yvonne A, Doroshow, James H, Welm, Alana L, Welm, Bryan E, Lewis, Michael T, Fang, Bingliang, Roth, Jack A, Meric-Bernstam, Funda, Herlyn, Meenhard, Davies, Michael A, Ding, Li, Li, Shunqiang, Govindan, Ramaswamy, Isella, Claudio, Moscow, Jeffrey A, Trusolino, Livio, Byrne, Annette T, Jonkers, Jos, Bult, Carol J, Medico, Enzo, Chuang, Jeffrey H
Published in Nature genetics (01.01.2021)
Published in Nature genetics (01.01.2021)
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Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP
Shen, Liangliang, O’Shea, John M., Kaadige, Mohan R., Cunha, Stéphanie, Wilde, Blake R., Cohen, Adam L., Welm, Alana L., Ayer, Donald E.
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2015)
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Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment
Sun, Hua, Cao, Song, Mashl, R Jay, Mo, Chia-Kuei, Zaccaria, Simone, Wendl, Michael C, Davies, Sherri R, Bailey, Matthew H, Primeau, Tina M, Hoog, Jeremy, Mudd, Jacqueline L, Dean, 2nd, Dennis A, Patidar, Rajesh, Chen, Li, Wyczalkowski, Matthew A, Jayasinghe, Reyka G, Rodrigues, Fernanda Martins, Terekhanova, Nadezhda V, Li, Yize, Lim, Kian-Huat, Wang-Gillam, Andrea, Van Tine, Brian A, Ma, Cynthia X, Aft, Rebecca, Fuh, Katherine C, Schwarz, Julie K, Zevallos, Jose P, Puram, Sidharth V, Dipersio, John F, Davis-Dusenbery, Brandi, Ellis, Matthew J, Lewis, Michael T, Davies, Michael A, Herlyn, Meenhard, Fang, Bingliang, Roth, Jack A, Welm, Alana L, Welm, Bryan E, Meric-Bernstam, Funda, Chen, Feng, Fields, Ryan C, Li, Shunqiang, Govindan, Ramaswamy, Doroshow, James H, Moscow, Jeffrey A, Evrard, Yvonne A, Chuang, Jeffrey H, Raphael, Benjamin J, Ding, Li
Published in Nature communications (24.08.2021)
Published in Nature communications (24.08.2021)
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Dll1 + quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway
Kumar, Sushil, Nandi, Ajeya, Singh, Snahlata, Regulapati, Rohan, Li, Ning, Tobias, John W, Siebel, Christian W, Blanco, Mario Andres, Klein-Szanto, Andres J, Lengner, Christopher, Welm, Alana L, Kang, Yibin, Chakrabarti, Rumela
Published in Nature communications (18.01.2021)
Published in Nature communications (18.01.2021)
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Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells
Tsai, Hsing-Chen, Li, Huili, Van Neste, Leander, Cai, Yi, Robert, Carine, Rassool, Feyruz V., Shin, James J., Harbom, Kirsten M., Beaty, Robert, Pappou, Emmanouil, Harris, James, Yen, Ray-Whay Chiu, Ahuja, Nita, Brock, Malcolm V., Stearns, Vered, Feller-Kopman, David, Yarmus, Lonny B., Lin, Yi-Chun, Welm, Alana L., Issa, Jean-Pierre, Minn, Il, Matsui, William, Jang, Yoon-Young, Sharkis, Saul J., Baylin, Stephen B., Zahnow, Cynthia A.
Published in Cancer cell (20.03.2012)
Published in Cancer cell (20.03.2012)
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CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide
Radhakrishnan, Sabarinath V, Luetkens, Tim, Scherer, Sandra D, Davis, Patricia, Vander Mause, Erica R, Olson, Michael L, Yousef, Sara, Panse, Jens, Abdiche, Yasmina, Li, K David, Miles, Rodney R, Matsui, William, Welm, Alana L, Atanackovic, Djordje
Published in Nature communications (07.02.2020)
Published in Nature communications (07.02.2020)
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Preclinical Evaluation of Fatty Acid Synthase and EGFR Inhibition in Triple-Negative Breast Cancer
Giró-Perafita, Ariadna, Palomeras, Sònia, Lum, David H, Blancafort, Adriana, Viñas, Gemma, Oliveras, Glòria, Pérez-Bueno, Ferran, Sarrats, Ariadna, Welm, Alana L, Puig, Teresa
Published in Clinical cancer research (15.09.2016)
Published in Clinical cancer research (15.09.2016)
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A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology
Guillen, Katrin P, Fujita, Maihi, Butterfield, Andrew J, Scherer, Sandra D, Bailey, Matthew H, Chu, Zhengtao, DeRose, Yoko S, Zhao, Ling, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Toner, Jennifer, Wang, Guoying, Qiao, Yi, Huang, Xiaomeng, Greenland, Jeffery A, Vahrenkamp, Jeffery M, Lum, David H, Factor, Rachel E, Nelson, Edward W, Matsen, Cindy B, Poretta, Jane M, Rosenthal, Regina, Beck, Anna C, Buys, Saundra S, Vaklavas, Christos, Ward, John H, Jensen, Randy L, Jones, Kevin B, Li, Zheqi, Oesterreich, Steffi, Dobrolecki, Lacey E, Pathi, Satya S, Woo, Xing Yi, Berrett, Kristofer C, Wadsworth, Mark E, Chuang, Jeffrey H, Lewis, Michael T, Marth, Gabor T, Gertz, Jason, Varley, Katherine E, Welm, Bryan E, Welm, Alana L
Published in Nature cancer (01.02.2022)
Published in Nature cancer (01.02.2022)
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An immune-humanized patient-derived xenograft model of estrogen-independent, hormone receptor positive metastatic breast cancer
Scherer, Sandra D, Riggio, Alessandra I, Haroun, Fadi, DeRose, Yoko S, Ekiz, H Atakan, Fujita, Maihi, Toner, Jennifer, Zhao, Ling, Li, Zheqi, Oesterreich, Steffi, Samatar, Ahmed A, Welm, Alana L
Published in Breast cancer research : BCR (30.10.2021)
Published in Breast cancer research : BCR (30.10.2021)
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Invasive Lobular Carcinoma Cell Lines Are Characterized by Unique Estrogen-Mediated Gene Expression Patterns and Altered Tamoxifen Response
SIKORA, Matthew J, COOPER, Kristine L, BAHREINI, Amir, LUTHRA, Soumya, GUOYING WANG, CHANDRAN, Uma R, DAVIDSON, Nancy E, DABBS, David J, WELM, Alana L, OESTERREICH, Steffi
Published in Cancer research (Chicago, Ill.) (01.03.2014)
Published in Cancer research (Chicago, Ill.) (01.03.2014)
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Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer
Palomeras, Sònia, Diaz-Lagares, Ángel, Viñas, Gemma, Setien, Fernando, Ferreira, Humberto J, Oliveras, Glòria, Crujeiras, Ana B, Hernández, Alejandro, Lum, David H, Welm, Alana L, Esteller, Manel, Puig, Teresa
Published in Breast cancer research : BCR (05.07.2019)
Published in Breast cancer research : BCR (05.07.2019)
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Journal Article
Protein Arginine Methyltransferase 5 Accelerates Tumor Growth by Arginine Methylation of the Tumor Suppressor Programmed Cell Death 4
POWERS, Matthew A, FAY, Marta M, FACTOR, Rachel E, WELM, Alana L, ULLMAN, Katharine S
Published in Cancer research (Chicago, Ill.) (15.08.2011)
Published in Cancer research (Chicago, Ill.) (15.08.2011)
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Transferred mitochondria accumulate reactive oxygen species, promoting proliferation
Kidwell, Chelsea U, Casalini, Joseph R, Pradeep, Soorya, Scherer, Sandra D, Greiner, Daniel, Bayik, Defne, Watson, Dionysios C, Olson, Gregory S, Lathia, Justin D, Johnson, Jarrod S, Rutter, Jared, Welm, Alana L, Zangle, Thomas A, Roh-Johnson, Minna
Published in eLife (06.03.2023)
Published in eLife (06.03.2023)
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