The state of the art in anti-malarial drug discovery and development
Burrows, Jeremy N, Chibale, Kelly, Wells, Timothy N C
Published in Current topics in medicinal chemistry (01.05.2011)
Published in Current topics in medicinal chemistry (01.05.2011)
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Journal Article
Malaria medicines: a glass half full?
Wells, Timothy N C, Hooft van Huijsduijnen, Rob, Van Voorhis, Wesley C
Published in Nature reviews. Drug discovery (01.06.2015)
Published in Nature reviews. Drug discovery (01.06.2015)
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Journal Article
New medicines to improve control and contribute to the eradication of malaria
Wells, Timothy N. C, Alonso, Pedro L, Gutteridge, Winston E
Published in Nature reviews. Drug discovery (01.11.2009)
Published in Nature reviews. Drug discovery (01.11.2009)
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Journal Article
Molnupiravir combined with different repurposed drugs further inhibits SARS-CoV-2 infection in human nasal epithelium in vitro
Jonsdottir, Hulda R., Siegrist, Denise, Julien, Thomas, Padey, Blandine, Bouveret, Mendy, Terrier, Olivier, Pizzorno, Andres, Huang, Song, Samby, Kirandeep, Wells, Timothy N.C., Boda, Bernadett, Rosa-Calatrava, Manuel, Engler, Olivier B., Constant, Samuel
Published in Biomedicine & pharmacotherapy (01.06.2022)
Published in Biomedicine & pharmacotherapy (01.06.2022)
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A Proposed Target Product Profile and Developmental Cascade for New Cryptosporidiosis Treatments
Huston, Christopher D, Spangenberg, Thomas, Burrows, Jeremy, Willis, Paul, Wells, Timothy N C, van Voorhis, Wesley
Published in PLoS neglected tropical diseases (01.10.2015)
Published in PLoS neglected tropical diseases (01.10.2015)
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Journal Article
Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis
Rufener, Reto, Dick, Luca, D'Ascoli, Laura, Ritler, Dominic, Hizem, Amani, Wells, Timothy N.C., Hemphill, Andrew, Lundström-Stadelmann, Britta
Published in International journal for parasitology -- drugs and drug resistance (01.12.2018)
Published in International journal for parasitology -- drugs and drug resistance (01.12.2018)
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Orally active antischistosomal early leads identified from the open access malaria box
Ingram-Sieber, Katrin, Cowan, Noemi, Panic, Gordana, Vargas, Mireille, Mansour, Nuha R, Bickle, Quentin D, Wells, Timothy N C, Spangenberg, Thomas, Keiser, Jennifer
Published in PLoS neglected tropical diseases (01.01.2014)
Published in PLoS neglected tropical diseases (01.01.2014)
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Screening of the ‘Pathogen Box’ identifies an approved pesticide with major anthelmintic activity against the barber's pole worm
Preston, Sarah, Jiao, Yaqing, Jabbar, Abdul, McGee, Sean L., Laleu, Benoît, Willis, Paul, Wells, Timothy N.C., Gasser, Robin B.
Published in International journal for parasitology -- drugs and drug resistance (01.12.2016)
Published in International journal for parasitology -- drugs and drug resistance (01.12.2016)
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Journal Article
Targeting the hypnozoite reservoir of Plasmodium vivax : the hidden obstacle to malaria elimination
Wells, Timothy N.C, Burrows, Jeremy N, Baird, J. Kevin
Published in Trends in parasitology (01.03.2010)
Published in Trends in parasitology (01.03.2010)
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Journal Article
Molecular Cloning and Characterization of a Highly Selective Chemokine-binding Protein from the Tick Rhipicephalus sanguineus
Frauenschuh, Achim, Power, Christine A., Déruaz, Maud, Ferreira, Beatriz R., Silva, João S., Teixeira, Mauro M., Dias, João M., Martin, Thierry, Wells, Timothy N.C., Proudfoot, Amanda E.I.
Published in The Journal of biological chemistry (14.09.2007)
Published in The Journal of biological chemistry (14.09.2007)
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Journal Article
The BBXB Motif of RANTES Is the Principal Site for Heparin Binding and Controls Receptor Selectivity
Proudfoot, Amanda E.I., Fritchley, Sarah, Borlat, Frédéric, Shaw, Jeffrey P., Vilbois, Francis, Zwahlen, Catherine, Trkola, Alexandra, Marchant, David, Clapham, Paul R., Wells, Timothy N.C.
Published in The Journal of biological chemistry (06.04.2001)
Published in The Journal of biological chemistry (06.04.2001)
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Journal Article
A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock
Chvatchko, Y, Hoogewerf, A J, Meyer, A, Alouani, S, Juillard, P, Buser, R, Conquet, F, Proudfoot, A E, Wells, T N, Power, C A
Published in The Journal of experimental medicine (15.05.2000)
Published in The Journal of experimental medicine (15.05.2000)
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Journal Article
The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness
Gonzalo, J A, Lloyd, C M, Wen, D, Albar, J P, Wells, T N, Proudfoot, A, Martinez-A, C, Dorf, M, Bjerke, T, Coyle, A J, Gutierrez-Ramos, J C
Published in The Journal of experimental medicine (06.07.1998)
Published in The Journal of experimental medicine (06.07.1998)
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Journal Article
Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity
Mack, M, Luckow, B, Nelson, P J, Cihak, J, Simmons, G, Clapham, P R, Signoret, N, Marsh, M, Stangassinger, M, Borlat, F, Wells, T N, Schlöndorff, D, Proudfoot, A E
Published in The Journal of experimental medicine (20.04.1998)
Published in The Journal of experimental medicine (20.04.1998)
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Journal Article
Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist
Simmons, Graham, Clapham, Paul R., Picard, Laurent, Offord, Robin E., Rosenkilde, Mette M., Schwartz, Thue W., Buser, Raphaële, Timothy N. C. Wells, Amanda E. I. Proudfoot
Published in Science (American Association for the Advancement of Science) (11.04.1997)
Published in Science (American Association for the Advancement of Science) (11.04.1997)
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Journal Article
RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis
Lloyd, C M, Minto, A W, Dorf, M E, Proudfoot, A, Wells, T N, Salant, D J, Gutierrez-Ramos, J C
Published in The Journal of experimental medicine (07.04.1997)
Published in The Journal of experimental medicine (07.04.1997)
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Journal Article
CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4
Endres, Michael J, Clapham, Paul R, Marsh, Mark, Ahuja, Ména, Turner, Julie Davis, McKnight, Aine, Thomas, Jill F, Stoebenau-Haggarty, Beth, Choe, Sunny, Vance, Patricia J, Wells, Timothy N.C, Power, Christine A, Sutterwala, Shaheen S, Doms, Robert W, Landau, Nathaniel R, Hoxie, James A
Published in Cell (15.11.1996)
Published in Cell (15.11.1996)
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