Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering
Maffioletti, Sara Martina, Sarcar, Shilpita, Henderson, Alexander B.H., Mannhardt, Ingra, Pinton, Luca, Moyle, Louise Anne, Steele-Stallard, Heather, Cappellari, Ornella, Wells, Kim E., Ferrari, Giulia, Mitchell, Jamie S., Tyzack, Giulia E., Kotiadis, Vassilios N., Khedr, Moustafa, Ragazzi, Martina, Wang, Weixin, Duchen, Michael R., Patani, Rickie, Zammit, Peter S., Wells, Dominic J., Eschenhagen, Thomas, Tedesco, Francesco Saverio
Published in Cell reports (Cambridge) (17.04.2018)
Published in Cell reports (Cambridge) (17.04.2018)
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Journal Article
The transgenic expression of LARGE exacerbates the muscle phenotype of dystroglycanopathy mice
Whitmore, Charlotte, Fernandez-Fuente, Marta, Booler, Helen, Parr, Callum, Kavishwar, Manoli, Ashraf, Attia, Lacey, Erica, Kim, Jihee, Terry, Rebecca, Ackroyd, Mark R, Wells, Kim E, Muntoni, Francesco, Wells, Dominic J, Brown, Susan C
Published in Human molecular genetics (01.04.2014)
Published in Human molecular genetics (01.04.2014)
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Journal Article
Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy
Betts, Corinne A., Saleh, Amer F., Carr, Carolyn A., Muses, Sofia, Wells, Kim E., Hammond, Suzan M., Godfrey, Caroline, McClorey, Graham, Woffindale, Caroline, Clarke, Kieran, Wells, Dominic J., Gait, Michael J., Wood, Matthew J. A.
Published in Scientific reports (26.06.2015)
Published in Scientific reports (26.06.2015)
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Journal Article
The Neuroprotective Effects of Heat Shock Protein 27 Overexpression in Transgenic Animals against Kainate-induced Seizures and Hippocampal Cell Death
Akbar, Mohammed T., Lundberg, Anna M.C., Liu, Ke, Vidyadaran, Sharmili, Wells, Kim E., Dolatshad, Hamid, Wynn, Sarah, Wells, Dominic J., Latchman, David S., de Belleroche, Jacqueline
Published in The Journal of biological chemistry (30.05.2003)
Published in The Journal of biological chemistry (30.05.2003)
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Journal Article
How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse
Godfrey, Caroline, Muses, Sofia, McClorey, Graham, Wells, Kim E, Coursindel, Thibault, Terry, Rebecca L, Betts, Corinne, Hammond, Suzan, O'Donovan, Liz, Hildyard, John, El Andaloussi, Samir, Gait, Michael J, Wood, Matthew J, Wells, Dominic J
Published in Human molecular genetics (01.08.2015)
Published in Human molecular genetics (01.08.2015)
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Journal Article
Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment
Betts, Corinne A, McClorey, Graham, Healicon, Richard, Hammond, Suzan M, Manzano, Raquel, Muses, Sofia, Ball, Vicky, Godfrey, Caroline, Merritt, Thomas M, van Westering, Tirsa, O'Donovan, Liz, Wells, Kim E, Gait, Michael J, Wells, Dominic J, Tyler, Damian, Wood, Matthew J
Published in Human molecular genetics (01.02.2019)
Published in Human molecular genetics (01.02.2019)
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Journal Article
Relocalization of neuronal nitric oxide synthase (nNOS) as a marker for complete restoration of the dystrophin associated protein complex in skeletal muscle
Wells, Kim E, Torelli, Silvia, Lu, Qi, Brown, Susan C, Partridge, Terence, Muntoni, Francesco, Wells, Dominic J
Published in Neuromuscular disorders : NMD (2003)
Published in Neuromuscular disorders : NMD (2003)
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Journal Article
Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy
Verhaart, Ingrid E.C., Cappellari, Ornella, Tanganyika-de Winter, Christa L., Plomp, Jaap J., Nnorom, Sofia, Wells, Kim E., Hildyard, John C.W., Bull, David, Aartsma-Rus, Annemieke, Wells, Dominic J.
Published in Journal of neuromuscular diseases (01.01.2021)
Published in Journal of neuromuscular diseases (01.01.2021)
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Journal Article
Gene delivery to dystrophic muscle
Wells, Kim E, McMahon, Jill, Foster, Helen, Ferrer, Aurora, Wells, Dominic J
Published in Methods in molecular biology (Clifton, N.J.) (2008)
Published in Methods in molecular biology (Clifton, N.J.) (2008)
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Journal Article
Immunological hurdles in the path to gene therapy for Duchenne muscular dystrophy
Wells, Dominic J., Ferrer, Aurora, Wells, Kim E.
Published in Expert reviews in molecular medicine (04.11.2002)
Published in Expert reviews in molecular medicine (04.11.2002)
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Journal Article
Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy
Wells, D J, Wells, K E, Asante, E A, Turner, G, Sunada, Y, Campbell, K P, Walsh, F S, Dickson, G
Published in Human molecular genetics (01.08.1995)
Published in Human molecular genetics (01.08.1995)
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Journal Article
Evaluation of Plasmid DNA for in Vivo Gene Therapy: Factors Affecting the Number of Transfected Fibers
Wells, Dominic J., Maule, Jake, McMahon, Jill, Mitchell, Roger, Damien, Elsie, Poole, Angie, Wells, Kim E.
Published in Journal of pharmaceutical sciences (01.06.1998)
Published in Journal of pharmaceutical sciences (01.06.1998)
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Journal Article
Independent localization of dystrophin N- and C-terminal regions to the sarcolemma of mdx mouse myofibres in vivo
DUNCKLEY, M. G, WELLS, K. E, PIPER, T. A, WELLS, D. J, DICKSON, G
Published in Journal of cell science (01.06.1994)
Published in Journal of cell science (01.06.1994)
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