Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics
Brown, Ryan, Nath, Sridesh, Lora, Alnardo, Samaha, Ghassan, Elgamal, Ziyad, Kaiser, Ryan, Taggart, Clifford, Weldon, Sinéad, Geraghty, Patrick
Published in Respiratory research (12.05.2020)
Published in Respiratory research (12.05.2020)
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Journal Article
Fasciola hepatica -Derived Molecules as Regulators of the Host Immune Response
Ryan, Sinéad, Shiels, Jenna, Taggart, Clifford C, Dalton, John P, Weldon, Sinéad
Published in Frontiers in immunology (02.09.2020)
Published in Frontiers in immunology (02.09.2020)
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Journal Article
The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung
Taggart, Clifford C., FitzGerald, S. Peter, Lowry, Philip, Brockbank, Simon, Twigg, Matthew S., Weldon, Sinéad
Published in Mediators of Inflammation (01.01.2015)
Published in Mediators of Inflammation (01.01.2015)
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Journal Article
Airway Inflammation and Host Responses in the Era of CFTR Modulators
Keown, Karen, Brown, Ryan, Doherty, Declan F, Houston, Claire, McKelvey, Michael C, Creane, Shannice, Linden, Dermot, McAuley, Daniel F, Kidney, Joseph C, Weldon, Sinéad, Downey, Damian G, Taggart, Clifford C
Published in International journal of molecular sciences (02.09.2020)
Published in International journal of molecular sciences (02.09.2020)
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Journal Article
SLPI and elafin: multifunctional antiproteases of the WFDC family
Scott, Aaron, Weldon, Sinéad, Taggart, Clifford C
Published in Biochemical Society transactions (01.10.2011)
Published in Biochemical Society transactions (01.10.2011)
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Journal Article
Proteases, Mucus, and Mucosal Immunity in Chronic Lung Disease
McKelvey, Michael C, Brown, Ryan, Ryan, Sinéad, Mall, Marcus A, Weldon, Sinéad, Taggart, Clifford C
Published in International journal of molecular sciences (09.05.2021)
Published in International journal of molecular sciences (09.05.2021)
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Journal Article
Decreased Levels of Secretory Leucoprotease Inhibitor in the Pseudomonas-Infected Cystic Fibrosis Lung Are Due to Neutrophil Elastase Degradation
Weldon, Sinead, McNally, Paul, McElvaney, Noel G, Elborn, J. Stuart, McAuley, Danny F, Wartelle, Julien, Belaaouaj, Abderrazzaq, Levine, Rodney L, Taggart, Clifford C
Published in The Journal of immunology (1950) (15.12.2009)
Published in The Journal of immunology (1950) (15.12.2009)
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Journal Article
PTEN Depletion Increases Radiosensitivity in Response to Ataxia Telangiectasia-Related-3 (ATR) Inhibition in Non-Small Cell Lung Cancer (NSCLC)
Dunne, Victoria L, Ghita-Pettigrew, Mihaela, Redmond, Kelly M, Small, Donna M, Weldon, Sinéad, Taggart, Clifford C, Prise, Kevin M, Hanna, Gerard G, Butterworth, Karl T
Published in International journal of molecular sciences (17.07.2024)
Published in International journal of molecular sciences (17.07.2024)
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Journal Article
SLPI deficiency alters airway protease activity and induces cell recruitment in a model of muco-obstructive lung disease
Brown, Ryan, Dougan, Caoifa, Ferris, Peter, Delaney, Rebecca, Houston, Claire J, Rodgers, Aoife, Downey, Damian G, Mall, Marcus A, Connolly, Bronwen, Small, Donna, Weldon, Sinéad, Taggart, Clifford C
Published in Frontiers in immunology (05.09.2024)
Published in Frontiers in immunology (05.09.2024)
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Journal Article
Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid
Weldon, Sinéad M., Mullen, Anne C., Loscher, Christine E., Hurley, Lisa A., Roche, Helen M.
Published in The Journal of nutritional biochemistry (01.04.2007)
Published in The Journal of nutritional biochemistry (01.04.2007)
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Journal Article
Deciphering Respiratory-Virus-Associated Interferon Signaling in COPD Airway Epithelium
Guo-Parke, Hong, Linden, Dermot, Weldon, Sinéad, Kidney, Joseph C, Taggart, Clifford C
Published in Medicina (Kaunas, Lithuania) (13.01.2022)
Published in Medicina (Kaunas, Lithuania) (13.01.2022)
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Journal Article
Sea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infection
Carlile, Simon R., Shiels, Jenna, Kerrigan, Lauren, Delaney, Rebecca, Megaw, Julianne, Gilmore, Brendan F., Weldon, Sinéad, Dalton, John P., Taggart, Clifford C.
Published in Scientific reports (15.04.2019)
Published in Scientific reports (15.04.2019)
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Journal Article
Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo
Scott, Aaron, Weldon, Sinéad, Buchanan, Paul J, Schock, Bettina, Ernst, Robert K, McAuley, Danny F, Tunney, Michael M, Irwin, Chris R, Elborn, J Stuart, Taggart, Clifford C
Published in PloS one (18.10.2011)
Published in PloS one (18.10.2011)
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Journal Article
miR-31 Dysregulation in Cystic Fibrosis Airways Contributes to Increased Pulmonary Cathepsin S Production
WELDON, Sinéad, MCNALLY, Paul, TAGGART, Clifford C, MCAULEY, Danny F, OGLESBY, Irene K, WOHLFORD-LENANE, Christine L, BARTLETT, Jennifer A, SCOTT, Christopher J, MCELVANEY, Noel G, GREENE, Catherine M, MCCRAY, Paul B
Published in American journal of respiratory and critical care medicine (15.07.2014)
Published in American journal of respiratory and critical care medicine (15.07.2014)
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Journal Article
Impaired Immune Tolerance to Porphyromonas gingivalis Lipopolysaccharide Promotes Neutrophil Migration and Decreased Apoptosis
Zaric, Svetislav, Shelburne, Charles, Darveau, Richard, Quinn, Derek J, Weldon, Sinéad, Taggart, Clifford C, Coulter, Wilson A
Published in Infection and Immunity (01.10.2010)
Published in Infection and Immunity (01.10.2010)
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Journal Article
Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice
Brown, Ryan, Small, Donna M., Doherty, Declan F., Holsinger, Leslie, Booth, Robert, Williams, Richard, Ingram, Rebecca J., Elborn, J. Stuart, Mall, Marcus A., Taggart, Clifford C., Weldon, Sinéad
Published in Mediators of inflammation (2021)
Published in Mediators of inflammation (2021)
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Journal Article
Secretory Leucoprotease Inhibitor (SLPI) Promotes Survival during Acute Pseudomonas aeruginosa Infection by Suppression of Inflammation Rather Than Microbial Killing
Osbourn, Megan, Rodgers, Aoife M, Dubois, Alice V, Small, Donna M, Humphries, Fiachra, Delagic, Nezira, Moynagh, Paul N, Weldon, Sinéad, Taggart, Clifford C, Ingram, Rebecca J
Published in Biomolecules (Basel, Switzerland) (22.11.2022)
Published in Biomolecules (Basel, Switzerland) (22.11.2022)
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Journal Article
Airway Epithelium Senescence as a Driving Mechanism in COPD Pathogenesis
Bateman, Georgia, Guo-Parke, Hong, Rodgers, Aoife M, Linden, Dermot, Bailey, Melanie, Weldon, Sinéad, Kidney, Joseph C, Taggart, Clifford C
Published in Biomedicines (01.07.2023)
Published in Biomedicines (01.07.2023)
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Journal Article
The Impact of Aging in Acute Respiratory Distress Syndrome: A Clinical and Mechanistic Overview
Brown, Ryan, McKelvey, Michael C, Ryan, Sinéad, Creane, Shannice, Linden, Dermot, Kidney, Joseph C, McAuley, Daniel F, Taggart, Clifford C, Weldon, Sinéad
Published in Frontiers in medicine (26.10.2020)
Published in Frontiers in medicine (26.10.2020)
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