Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis
Leboucher, Guillaume P., Tsai, Yien Che, Yang, Mei, Shaw, Kristin C., Zhou, Ming, Veenstra, Timothy D., Glickman, Michael H., Weissman, Allan M.
Published in Molecular cell (24.08.2012)
Published in Molecular cell (24.08.2012)
Get full text
Journal Article
A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms
Metzger, Meredith B., Liang, Yu-He, Das, Ranabir, Mariano, Jennifer, Li, Shengjian, Li, Jess, Kostova, Zlatka, Byrd, R. Andrew, Ji, Xinhua, Weissman, Allan M.
Published in Molecular cell (23.05.2013)
Published in Molecular cell (23.05.2013)
Get full text
Journal Article
A protein quality control pathway at the mitochondrial outer membrane
Metzger, Meredith B, Scales, Jessica L, Dunklebarger, Mitchell F, Loncarek, Jadranka, Weissman, Allan M
Published in eLife (02.03.2020)
Published in eLife (02.03.2020)
Get full text
Journal Article
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
Marie, Kerrie L., Sassano, Antonella, Yang, Howard H., Michalowski, Aleksandra M., Michael, Helen T., Guo, Theresa, Tsai, Yien Che, Weissman, Allan M., Lee, Maxwell P., Jenkins, Lisa M., Zaidi, M. Raza, Pérez-Guijarro, Eva, Day, Chi-Ping, Ylaya, Kris, Hewitt, Stephen M., Patel, Nimit L., Arnheiter, Heinz, Davis, Sean, Meltzer, Paul S., Merlino, Glenn, Mishra, Pravin J.
Published in Nature communications (16.01.2020)
Published in Nature communications (16.01.2020)
Get full text
Journal Article
A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation
Smith, Christopher E, Tsai, Yien Che, Liang, Yu-He, Khago, Domarin, Mariano, Jennifer, Li, Jess, Tarasov, Sergey G, Gergel, Emma, Tsai, Borong, Villaneuva, Matthew, Clapp, Michelle E, Magidson, Valentin, Chari, Raj, Byrd, R Andrew, Ji, Xinhua, Weissman, Allan M
Published in PLoS biology (08.12.2021)
Published in PLoS biology (08.12.2021)
Get full text
Journal Article
Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication
Tsai, Yien Che, Kotiya, Archana, Kiris, Erkan, Yang, Mei, Bavari, Sina, Tessarollo, Lino, Oyler, George A., Weissman, Allan M.
Published in Proceedings of the National Academy of Sciences - PNAS (27.06.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (27.06.2017)
Get full text
Journal Article
HECT and RING finger families of E3 ubiquitin ligases at a glance
Metzger, Meredith B, Hristova, Ventzislava A, Weissman, Allan M
Published in Journal of cell science (01.02.2012)
Published in Journal of cell science (01.02.2012)
Get full text
Journal Article
Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling
Kulkarni, Rhushikesh A., Worth, Andrew J., Zengeya, Thomas T., Shrimp, Jonathan H., Garlick, Julie M., Roberts, Allison M., Montgomery, David C., Sourbier, Carole, Gibbs, Benjamin K., Mesaros, Clementina, Tsai, Yien Che, Das, Sudipto, Chan, King C., Zhou, Ming, Andresson, Thorkell, Weissman, Allan M., Linehan, W. Marston, Blair, Ian A., Snyder, Nathaniel W., Meier, Jordan L.
Published in Cell chemical biology (16.02.2017)
Published in Cell chemical biology (16.02.2017)
Get full text
Journal Article
Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
Magnussen, Helge M., Ahmed, Syed F., Sibbet, Gary. J., Hristova, Ventzislava A., Nomura, Koji, Hock, Andreas K., Archibald, Lewis J., Jamieson, Andrew G., Fushman, David, Vousden, Karen H., Weissman, Allan M., Huang, Danny T.
Published in Nature communications (29.04.2020)
Published in Nature communications (29.04.2020)
Get full text
Journal Article
Differences in the tumor microenvironment between African-American and European-American breast cancer patients
Martin, Damali N, Boersma, Brenda J, Yi, Ming, Reimers, Mark, Howe, Tiffany M, Yfantis, Harry G, Tsai, Yien Che, Williams, Erica H, Lee, Dong H, Stephens, Robert M, Weissman, Allan M, Ambs, Stefan
Published in PloS one (19.02.2009)
Published in PloS one (19.02.2009)
Get full text
Journal Article
Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics
YANG, Yili, KITAGAKI, Jirouta, LI, Chou-Chi H, KENTEN, John H, BEUTLER, John A, VOUSDEN, Karen H, WEISSMAN, Allan M, DAI, Ren-Ming, YIEN CHE TSAI, LORICK, Kevin L, LUDWIG, Robert L, PIERRE, Shervon A, JENSEN, Jane P, DAVYDOV, Ilia V, OBEROI, Pankaj
Published in Cancer research (Chicago, Ill.) (01.10.2007)
Published in Cancer research (Chicago, Ill.) (01.10.2007)
Get full text
Journal Article
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
Kostova, Zlatka, Tsai, Yien Che, Weissman, Allan M.
Published in Seminars in cell & developmental biology (01.12.2007)
Published in Seminars in cell & developmental biology (01.12.2007)
Get full text
Journal Article
Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78
Das, Ranabir, Mariano, Jennifer, Tsai, Yien Che, Kalathur, Ravi C., Kostova, Zlatka, Li, Jess, Tarasov, Sergey G., McFeeters, Robert L., Altieri, Amanda S., Ji, Xinhua, Byrd, R. Andrew, Weissman, Allan M.
Published in Molecular cell (26.06.2009)
Published in Molecular cell (26.06.2009)
Get full text
Journal Article
Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system
Tsai, Yien Che, Leichner, Gil S, Pearce, Margaret M P, Wilson, Gaye Lynn, Wojcikiewicz, Richard J H, Roitelman, Joseph, Weissman, Allan M
Published in Molecular biology of the cell (01.12.2012)
Published in Molecular biology of the cell (01.12.2012)
Get full text
Journal Article
An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion
Cavellini, Laetitia, Meurisse, Julie, Findinier, Justin, Erpapazoglou, Zoi, Belgareh-Touzé, Naïma, Weissman, Allan M., Cohen, Mickael M.
Published in Nature communications (13.06.2017)
Published in Nature communications (13.06.2017)
Get full text
Journal Article