Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice
Sendler, Matthias, Weiss, Frank-Ulrich, Golchert, Janine, Homuth, Georg, van den Brandt, Cindy, Mahajan, Ujjwal M., Partecke, Lars-Ivo, Döring, Paula, Gukovsky, Ilya, Gukovskaya, Anna S., Wagh, Preshit R., Lerch, Markus M., Mayerle, Julia
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2018)
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Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer
Aghdassi, Ali, Sendler, Matthias, Guenther, Annett, Mayerle, Julia, Behn, Claas-Olsen, Heidecke, Claus-Dieter, Friess, Helmut, Büchler, Markus, Evert, Matthias, Lerch, Markus M, Weiss, Frank Ulrich
Published in Gut (01.03.2012)
Published in Gut (01.03.2012)
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Tumor-Specific Delivery of 5-Fluorouracil–Incorporated Epidermal Growth Factor Receptor–Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models
Mahajan, Ujjwal M., Li, Qi, Alnatsha, Ahmed, Maas, Jessica, Orth, Michael, Maier, Sebastian Hubertus, Peterhansl, Julian, Regel, Ivonne, Sendler, Matthias, Wagh, Preshit R., Mishra, Neha, Xue, Yonggan, Allawadhi, Prince, Beyer, Georg, Kühn, Jens-Peter, Marshall, Thomas, Appel, Bettina, Lämmerhirt, Felix, Belka, Claus, Müller, Sabine, Weiss, Frank-Ulrich, Lauber, Kirsten, Lerch, Markus M., Mayerle, Julia
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2021)
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Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: A novel disease mechanism
Kereszturi, Éva, Szmola, Richárd, Kukor, Zoltán, Simon, Peter, Ulrich Weiss, Frank, Lerch, Markus M, Sahin-Tóth, Miklós
Published in Human mutation (01.04.2009)
Published in Human mutation (01.04.2009)
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Plasma Metabolome Profiling Identifies Metabolic Subtypes of Pancreatic Ductal Adenocarcinoma
Mahajan, Ujjwal Mukund, Alnatsha, Ahmed, Li, Qi, Oehrle, Bettina, Weiss, Frank-Ulrich, Sendler, Matthias, Distler, Marius, Uhl, Waldemar, Fahlbusch, Tim, Goni, Elisabetta, Beyer, Georg, Chromik, Ansgar, Bahra, Markus, Klein, Fritz, Pilarsky, Christian, Grützmann, Robert, Lerch, Markus M, Lauber, Kirsten, Christiansen, Nicole, Kamlage, Beate, Regel, Ivonne, Mayerle, Julia
Published in Cells (Basel, Switzerland) (19.07.2021)
Published in Cells (Basel, Switzerland) (19.07.2021)
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Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration
Arnold, Frank, Mahaddalkar, Pallavi U, Kraus, Johann M., Zhong, Xiaowei, Bergmann, Wendy, Srinivasan, Dharini, Gout, Johann, Roger, Elodie, Beutel, Alica K., Zizer, Eugen, Tharehalli, Umesh, Daiss, Nora, Russell, Ronan, Perkhofer, Lukas, Oellinger, Rupert, Lin, Qiong, Azoitei, Ninel, Weiss, Frank‐Ulrich, Lerch, Markus M., Liebau, Stefan, Katz, Sarah‐Fee, Lechel, André, Rad, Roland, Seufferlein, Thomas, Kestler, Hans A., Ott, Michael, Sharma, Amar Deep, Hermann, Patrick C., Kleger, Alexander
Published in Advanced science (01.07.2021)
Published in Advanced science (01.07.2021)
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A rare PRSS1 p.S127C mutation is associated with chronic pancreatitis and causes misfolding-induced ER-stress
Thiel, Franziska, Reiser, Markus, Weiss, Frank Ulrich
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2022)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2022)
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Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis
Glaubitz, Juliane, Wilden, Anika, Frost, Fabian, Ameling, Sabine, Homuth, Georg, Mazloum, Hala, Rühlemann, Malte Christoph, Bang, Corinna, Aghdassi, Ali A, Budde, Christoph, Pickartz, Tilmann, Franke, Andre, Bröker, Barbara M, Voelker, Uwe, Mayerle, Julia, Lerch, Markus M, Weiss, Frank-Ulrich, Sendler, Matthias
Published in Gut (01.07.2023)
Published in Gut (01.07.2023)
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Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma
Mahajan, Ujjwal Mukund, Langhoff, Eno, Goni, Elisabetta, Costello, Eithne, Greenhalf, William, Halloran, Christopher, Ormanns, Steffen, Kruger, Stephan, Boeck, Stefan, Ribback, Silvia, Beyer, Georg, Dombroswki, Frank, Weiss, Frank-Ulrich, Neoptolemos, John P., Werner, Jens, D’Haese, Jan G., Bazhin, Alexandr, Peterhansl, Julian, Pichlmeier, Svenja, Büchler, Markus W., Kleeff, Jörg, Ganeh, Paula, Sendler, Matthias, Palmer, Daniel H., Kohlmann, Thomas, Rad, Roland, Regel, Ivonne, Lerch, Markus M., Mayerle, Julia
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2018)
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Tissue tolerable plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo
Partecke, Lars Ivo, Evert, Katja, Haugk, Jan, Doering, Friderike, Normann, Lars, Diedrich, Stephan, Weiss, Frank-Ulrich, Evert, Matthias, Huebner, Nils Olaf, Guenther, Cristin, Heidecke, Claus Dieter, Kramer, Axel, Bussiahn, René, Weltmann, Klaus-Dieter, Pati, Onur, Bender, Claudia, von Bernstorff, Wolfram
Published in BMC cancer (15.10.2012)
Published in BMC cancer (15.10.2012)
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Etiology and Risk Factors of Acute and Chronic Pancreatitis
Weiss, Frank Ulrich, Laemmerhirt, Felix, Lerch, Markus M.
Published in Visceral medicine (01.04.2019)
Published in Visceral medicine (01.04.2019)
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Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer
Mahajan, Ujjwal M, Teller, Steffen, Sendler, Matthias, Palankar, Raghavendra, van den Brandt, Cindy, Schwaiger, Theresa, Kühn, Jens-Peter, Ribback, Silvia, Glöckl, Gunnar, Evert, Matthias, Weitschies, Werner, Hosten, Norbert, Dombrowski, Frank, Delcea, Mihaela, Weiss, Frank-Ulrich, Lerch, Markus M, Mayerle, Julia
Published in Gut (01.11.2016)
Published in Gut (01.11.2016)
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IRAK3-mediated suppression of pro-inflammatory MyD88/IRAK signaling affects disease severity in acute pancreatitis
Thiel, Franziska G, Asgarbeik, Saeedeh, Glaubitz, Juliane, Wilden, Anika, Lerch, Markus M, Weiss, Frank Ulrich, Sendler, Matthias
Published in Scientific reports (04.07.2023)
Published in Scientific reports (04.07.2023)
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Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis
Sendler, Matthias, Beyer, Georg, Mahajan, Ujjwal M, Kauschke, Vivien, Maertin, Sandrina, Schurmann, Claudia, Homuth, Georg, Völker, Uwe, Völzke, Henry, Halangk, Walter, Wartmann, Thomas, Weiss, Frank-Ulrich, Hegyi, Peter, Lerch, Markus M, Mayerle, Julia
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2015)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2015)
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Immune response mechanisms in acute and chronic pancreatitis: strategies for therapeutic intervention
Glaubitz, Juliane, Asgarbeik, Saeedeh, Lange, Rabea, Mazloum, Hala, Elsheikh, Hager, Weiss, Frank Ulrich, Sendler, Matthias
Published in Frontiers in immunology (10.10.2023)
Published in Frontiers in immunology (10.10.2023)
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Independent Validation and Assay Standardization of Improved Metabolic Biomarker Signature to Differentiate Pancreatic Ductal Adenocarcinoma From Chronic Pancreatitis
Mahajan, Ujjwal M., Oehrle, Bettina, Sirtl, Simon, Alnatsha, Ahmed, Goni, Elisabetta, Regel, Ivonne, Beyer, Georg, Vornhülz, Marlies, Vielhauer, Jakob, Chromik, Ansgar, Bahra, Markus, Klein, Fritz, Uhl, Waldemar, Fahlbusch, Tim, Distler, Marius, Weitz, Jürgen, Grützmann, Robert, Pilarsky, Christian, Weiss, Frank Ulrich, Adam, M. Gordian, Neoptolemos, John P., Kalthoff, Holger, Rad, Roland, Christiansen, Nicole, Bethan, Bianca, Kamlage, Beate, Lerch, Markus M., Mayerle, Julia
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2022)
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Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer
Weiss, Frank Ulrich, Marques, Ines J, Woltering, Joost M, Vlecken, Danielle H, Aghdassi, Ali, Partecke, Lars Ivo, Heidecke, Claus-Dieter, Lerch, Markus M, Bagowski, Christoph P
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2009)
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Identification of Genetic Loci Associated With Helicobacter pylori Serologic Status
Mayerle, Julia, den Hoed, Caroline M, Schurmann, Claudia, Stolk, Lisette, Homuth, Georg, Peters, Marjolein J, Capelle, Lisette G, Zimmermann, Kathrin, Rivadeneira, Fernando, Gruska, Sybille, Völzke, Henry, de Vries, Annemarie C, Völker, Uwe, Teumer, Alexander, van Meurs, Joyce B. J, Steinmetz, Ivo, Nauck, Matthias, Ernst, Florian, Weiss, Frank-Ulrich, Hofman, Albert, Zenker, Martin, Kroemer, Heyo K, Prokisch, Holger, Uitterlinden, Andre G, Lerch, Markus M, Kuipers, Ernst
Published in JAMA : the journal of the American Medical Association (08.05.2013)
Published in JAMA : the journal of the American Medical Association (08.05.2013)
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Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis
Aghdassi, Ali A, John, Daniel S, Sendler, Matthias, Storck, Christian, van den Brandt, Cindy, Krüger, Burkhard, Weiss, Frank Ulrich, Mayerle, Julia, Lerch, Markus M
Published in Scientific reports (14.11.2019)
Published in Scientific reports (14.11.2019)
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