Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers
Hnisz, Denes, Schuijers, Jurian, Lin, Charles Y., Weintraub, Abraham S., Abraham, Brian J., Lee, Tong Ihn, Bradner, James E., Young, Richard A.
Published in Molecular cell (16.04.2015)
Published in Molecular cell (16.04.2015)
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Journal Article
Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes
Dowen, Jill M., Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J., Zhang, Lyndon N., Weintraub, Abraham S., Schuijers, Jurian, Lee, Tong Ihn, Zhao, Keji, Young, Richard A.
Published in Cell (09.10.2014)
Published in Cell (09.10.2014)
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Journal Article
Activation of proto-oncogenes by disruption of chromosome neighborhoods
Hnisz, Denes, Weintraub, Abraham S., Day, Daniel S., Valton, Anne-Laure, Bak, Rasmus O., Li, Charles H., Goldmann, Johanna, Lajoie, Bryan R., Fan, Zi Peng, Sigova, Alla A., Reddy, Jessica, Borges-Rivera, Diego, Lee, Tong Ihn, Jaenisch, Rudolf, Porteus, Matthew H., Dekker, Job, Young, Richard A.
Published in Science (American Association for the Advancement of Science) (25.03.2016)
Published in Science (American Association for the Advancement of Science) (25.03.2016)
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Journal Article
3D Chromosome Regulatory Landscape of Human Pluripotent Cells
Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.
Published in Cell stem cell (04.02.2016)
Published in Cell stem cell (04.02.2016)
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Journal Article
YY1 Is a Structural Regulator of Enhancer-Promoter Loops
Weintraub, Abraham S., Li, Charles H., Zamudio, Alicia V., Sigova, Alla A., Hannett, Nancy M., Day, Daniel S., Abraham, Brian J., Cohen, Malkiel A., Nabet, Behnam, Buckley, Dennis L., Guo, Yang Eric, Hnisz, Denes, Jaenisch, Rudolf, Bradner, James E., Gray, Nathanael S., Young, Richard A.
Published in Cell (14.12.2017)
Published in Cell (14.12.2017)
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Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas
Clark, Victoria E, Harmancı, Akdes Serin, Bai, Hanwen, Youngblood, Mark W, Lee, Tong Ihn, Baranoski, Jacob F, Ercan-Sencicek, A Gulhan, Abraham, Brian J, Weintraub, Abraham S, Hnisz, Denes, Simon, Matthias, Krischek, Boris, Erson-Omay, E Zeynep, Henegariu, Octavian, Carrión-Grant, Geneive, Mishra-Gorur, Ketu, Durán, Daniel, Goldmann, Johanna E, Schramm, Johannes, Goldbrunner, Roland, Piepmeier, Joseph M, Vortmeyer, Alexander O, Günel, Jennifer Moliterno, Bilgüvar, Kaya, Yasuno, Katsuhito, Young, Richard A, Günel, Murat
Published in Nature genetics (01.10.2016)
Published in Nature genetics (01.10.2016)
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Journal Article
Small genomic insertions form enhancers that misregulate oncogenes
Abraham, Brian J., Hnisz, Denes, Weintraub, Abraham S., Kwiatkowski, Nicholas, Li, Charles H., Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Lee, Tong Ihn, Zhang, Jinghui, Look, A. Thomas, Mansour, Marc R., Young, Richard A.
Published in Nature communications (09.02.2017)
Published in Nature communications (09.02.2017)
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Journal Article
Regulatory architecture of housekeeping genes is driven by promoter assemblies
Dejosez, Marion, Dall’Agnese, Alessandra, Ramamoorthy, Mahesh, Platt, Jesse, Yin, Xing, Hogan, Megan, Brosh, Ran, Weintraub, Abraham S., Hnisz, Denes, Abraham, Brian J., Young, Richard A., Zwaka, Thomas P.
Published in Cell reports (Cambridge) (30.05.2023)
Published in Cell reports (Cambridge) (30.05.2023)
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Journal Article
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
Adane, Biniam, Alexe, Gabriela, Seong, Bo Kyung A., Lu, Diana, Hwang, Elizabeth E., Hnisz, Denes, Lareau, Caleb A., Ross, Linda, Lin, Shan, Dela Cruz, Filemon S., Richardson, Melissa, Weintraub, Abraham S., Wang, Sarah, Iniguez, Amanda Balboni, Dharia, Neekesh V., Conway, Amy Saur, Robichaud, Amanda L., Tanenbaum, Benjamin, Krill-Burger, John M., Vazquez, Francisca, Schenone, Monica, Berman, Jason N., Kung, Andrew L., Carr, Steven A., Aryee, Martin J., Young, Richard A., Crompton, Brian D., Stegmaier, Kimberly
Published in Cancer cell (14.06.2021)
Published in Cancer cell (14.06.2021)
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Journal Article
PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes
Soto-Feliciano, Yadira M, Bartlebaugh, Jordan M E, Liu, Yunpeng, Sánchez-Rivera, Francisco J, Bhutkar, Arjun, Weintraub, Abraham S, Buenrostro, Jason D, Cheng, Christine S, Regev, Aviv, Jacks, Tyler E, Young, Richard A, Hemann, Michael T
Published in Genes & development (15.05.2017)
Published in Genes & development (15.05.2017)
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Journal Article
Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism
Schuijers, Jurian, Manteiga, John Colonnese, Weintraub, Abraham Selby, Day, Daniel Sindt, Zamudio, Alicia Viridiana, Hnisz, Denes, Lee, Tong Ihn, Young, Richard Allen
Published in Cell reports (Cambridge) (10.04.2018)
Published in Cell reports (Cambridge) (10.04.2018)
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Journal Article
Abstract 2004: Nucleation of transcriptional super-enhancers at tumor oncogenes by small insertions
Abraham, Brian J., Hnisz, Denes, Weintraub, Abraham S., Kwiatkowski, Nicholas, Li, Charles H., Rahman, Sunniyat, Li, Zhaodong, Lee, Tong Ihn, Look, A Thomas, Mansour, Marc, Young, Richard A.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Corrigendum: Small genomic insertions form enhancers that misregulate oncogenes
Abraham, Brian J, Hnisz, Denes, Weintraub, Abraham S, Kwiatkowski, Nicholas, Li, Charles H, Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Lee, Tong Ihn, Zhang, Jinghui, Look, A Thomas, Mansour, Marc R, Young, Richard A
Published in Nature communications (01.06.2017)
Published in Nature communications (01.06.2017)
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Journal Article
Correction: Corrigendum: Small genomic insertions form enhancers that misregulate oncogenes
Abraham, Brian J., Hnisz, Denes, Weintraub, Abraham S., Kwiatkowski, Nicholas, Li, Charles H., Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Lee, Tong Ihn, Zhang, Jinghui, Look, A. Thomas, Mansour, Marc R., Young, Richard A.
Published in Nature communications (01.06.2017)
Published in Nature communications (01.06.2017)
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Journal Article
Abstract 971: Three-dimensional gene regulatory landscapes in normal and cancer cells
Abraham, Brian J., Guo, Yang Eric, Hnisz, Denes, Li, Charles H., Weintraub, Abraham S., Day, Daniel S., Schuijers, Jurian, Lee, Tong Ihn, Young, Richard A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 5488: APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL
Li, Zhaodong, Abraham, Brian, Berezovskaya, Alla, Farah, Nadine, Liu, Yu, Leon, Theresa, Fielding, Adele, Tan, Shi Hao, Sanda, Takaomi, Weintraub, Abraham, Li, Benshang, Shen, Shuhong, Zhang, Jinghui, Mansour, Marc, Young, Richard, Look, Thomas
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract A44: The role of PHF6 in maintaining pre-B cell commitment in B-cell acute lymphoblastic leukemia
Soto-Feliciano, Yadira M., Bartlebaugh, Jordan ME, Liu, Yunpeng, Sánchez-Rivera, Francisco J., Weintraub, Abraham S., Bhutkar, Arjun, Jacks, Tyler E., Young, Richard A., Hemann, Michael T.
Published in Cancer research (Chicago, Ill.) (15.01.2016)
Published in Cancer research (Chicago, Ill.) (15.01.2016)
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