De novo-designed transmembrane domains tune engineered receptor functions
Elazar, Assaf, Chandler, Nicholas J, Davey, Ashleigh S, Weinstein, Jonathan Y, Nguyen, Julie V, Trenker, Raphael, Cross, Ryan S, Jenkins, Misty R, Call, Melissa J, Call, Matthew E, Fleishman, Sarel J
Published in eLife (04.05.2022)
Published in eLife (04.05.2022)
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Journal Article
Computational design of BclxL inhibitors that target transmembrane domain interactions
Duart, Gerard, Elazar, Assaf, Weinstein, Jonathan Y, Gadea-Salom, Laura, Ortiz-Mateu, Juan, Fleishman, Sarel J, Mingarro, Ismael, Martinez-Gil, Luis
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2023)
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Journal Article
Combined Crystal Structure of a Type I Cohesin: MUTATION AND AFFINITY BINDING STUDIES REVEAL STRUCTURAL DETERMINANTS OF COHESIN-DOCKERIN SPECIFICITIES
Cameron, Kate, Weinstein, Jonathan Y, Zhivin, Olga, Bule, Pedro, Fleishman, Sarel J, Alves, Victor D, Gilbert, Harry J, Ferreira, Luís M A, Fontes, Carlos M G A, Bayer, Edward A, Najmudin, Shabir
Published in The Journal of biological chemistry (26.06.2015)
Published in The Journal of biological chemistry (26.06.2015)
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Journal Article
Insights into a type III cohesin-dockerin recognition interface from the cellulose-degrading bacterium Ruminococcus flavefaciens
Weinstein, Jonathan Y., Slutzki, Michal, Karpol, Alon, Barak, Yoav, Gul, Ozgur, Lamed, Raphael, Bayer, Edward A., Fried, Daniel B.
Published in Journal of molecular recognition (01.03.2015)
Published in Journal of molecular recognition (01.03.2015)
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Journal Article
Combined Crystal Structure of a Type I Cohesin
Cameron, Kate, Weinstein, Jonathan Y., Zhivin, Olga, Bule, Pedro, Fleishman, Sarel J., Alves, Victor D., Gilbert, Harry J., Ferreira, Luís M.A., Fontes, Carlos M.G.A., Bayer, Edward A., Najmudin, Shabir
Published in The Journal of biological chemistry (26.06.2015)
Published in The Journal of biological chemistry (26.06.2015)
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Journal Article
Compositions for diagnosis and treatment of coronavirus infections
Ron DISKIN, Sarel FLEISHMAN, Jonathan Y. WEINSTEIN, Hadas COHEN-DVASHI
Year of Publication 01.03.2022
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Year of Publication 01.03.2022
Patent
COMPOSITIONS FOR DIAGNOSIS AND TREATMENT OF CORONAVIRUS INFECTIONS
WEINSTEIN, Jonathan Y, COHEN-DVASHI, Hadas, FLEISHMAN, Sarel, DISKIN, Ron
Year of Publication 17.02.2022
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Year of Publication 17.02.2022
Patent
De-novo designed transmembrane polypeptides and their uses in cellular immunotherapy
Sarel FLEISHMAN, Nicholas J. CHANDLER, Melissa J. CALL, Assaf ELAZAR, Jonathan Y. WEINSTEIN, Matthew E. CALL
Year of Publication 01.12.2021
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Year of Publication 01.12.2021
Patent
De novo designed receptor transmembrane domains enhance CAR-T cell cytotoxicity and attenuate cytokine release
Assaf Elazar, Chandler, Nicholas J, Davey, Ashleigh S, Weinstein, Jonathan Y, Nguyen, Julie V, Trenker, Raphael, Jenkins, Misty R, Call, Melissa J, Call, Matthew E, Fleishman, Sarel J
Published in bioRxiv (26.07.2020)
Published in bioRxiv (26.07.2020)
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Paper