Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology
Kaddurah-Daouk, R, Weinshilboum, R M
Published in Clinical pharmacology and therapeutics (01.02.2014)
Published in Clinical pharmacology and therapeutics (01.02.2014)
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TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics
Gupta, M, Neavin, D, Liu, D, Biernacka, J, Hall-Flavin, D, Bobo, W V, Frye, M A, Skime, M, Jenkins, G D, Batzler, A, Kalari, K, Matson, W, Bhasin, S S, Zhu, H, Mushiroda, T, Nakamura, Y, Kubo, M, Wang, L, Kaddurah-Daouk, R, Weinshilboum, R M
Published in Molecular psychiatry (01.12.2016)
Published in Molecular psychiatry (01.12.2016)
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FRI0046 PHARMACOGENOMICS-DRIVEN INDIVIDUALIZED PREDICTION OF TREATMENT RESPONSE TO METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS: A MACHINE LEARNING APPROACH
Myasoedova, E., Athreya, A., Crowson, C. S., Weinshilboum, R., Wang, L., Matteson, E.
Published in Annals of the rheumatic diseases (01.06.2020)
Published in Annals of the rheumatic diseases (01.06.2020)
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Thiopurine Pharmacogenetics: Clinical and Molecular Studies of Thiopurine Methyltransferase
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Conference Proceeding
A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate–prednisone
Wang, L., Dehm, S.M., Hillman, D.W., Sicotte, H., Tan, W., Gormley, M., Bhargava, V., Jimenez, R., Xie, F., Yin, P., Qin, S., Quevedo, F., Costello, B.A., Pitot, H.C., Ho, T., Bryce, A.H., Ye, Z., Li, Y., Eiken, P., Vedell, P.T., Barman, P., McMenomy, B.P., Atwell, T.D., Carlson, R.E., Ellingson, M., Eckloff, B.W., Qin, R., Ou, F., Hart, S.N., Huang, H., Jen, J., Wieben, E.D., Kalari, K.R., Weinshilboum, R.M., Wang, L., Kohli, M.
Published in Annals of oncology (01.02.2018)
Published in Annals of oncology (01.02.2018)
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Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics
Ji, Y, Hebbring, S, Zhu, H, Jenkins, G D, Biernacka, J, Snyder, K, Drews, M, Fiehn, O, Zeng, Z, Schaid, D, Mrazek, D A, Kaddurah-Daouk, R, Weinshilboum, R M
Published in Clinical pharmacology and therapeutics (01.01.2011)
Published in Clinical pharmacology and therapeutics (01.01.2011)
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The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response
Biernacka, J M, Sangkuhl, K, Jenkins, G, Whaley, R M, Barman, P, Batzler, A, Altman, R B, Arolt, V, Brockmöller, J, Chen, C H, Domschke, K, Hall-Flavin, D K, Hong, C J, Illi, A, Ji, Y, Kampman, O, Kinoshita, T, Leinonen, E, Liou, Y J, Mushiroda, T, Nonen, S, Skime, M K, Wang, L, Baune, B T, Kato, M, Liu, Y L, Praphanphoj, V, Stingl, J C, Tsai, S J, Kubo, M, Klein, T E, Weinshilboum, R
Published in Translational psychiatry (21.04.2015)
Published in Translational psychiatry (21.04.2015)
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Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study
Schmiegelow, K, Forestier, E, Kristinsson, J, Söderhäll, S, Vettenranta, K, Weinshilboum, R, Wesenberg, F
Published in Leukemia (01.03.2009)
Published in Leukemia (01.03.2009)
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The pharmacogenetics research network: from SNP discovery to clinical drug response
Giacomini, K M, Brett, C M, Altman, R B, Benowitz, N L, Dolan, M E, Flockhart, D A, Johnson, J A, Hayes, D F, Klein, T, Krauss, R M, Kroetz, D L, McLeod, H L, Nguyen, A T, Ratain, M J, Relling, M V, Reus, V, Roden, D M, Schaefer, C A, Shuldiner, A R, Skaar, T, Tantisira, K, Tyndale, R F, Wang, L, Weinshilboum, R M, Weiss, S T, Zineh, I
Published in Clinical pharmacology and therapeutics (01.03.2007)
Published in Clinical pharmacology and therapeutics (01.03.2007)
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CYP2D6 Genotype, Antidepressant Use, and Tamoxifen Metabolism During Adjuvant Breast Cancer Treatment
Jin, Yan, Desta, Zeruesenay, Stearns, Vered, Ward, Bryan, Ho, Herbert, Lee, Kyung-Hoon, Skaar, Todd, Storniolo, Anna Maria, Li, Lang, Araba, Adjei, Blanchard, Rebecca, Nguyen, Anne, Ullmer, Lynda, Hayden, Jill, Lemler, Suzanne, Weinshilboum, Richard M., Rae, James M., Hayes, Daniel F., Flockhart, David A.
Published in JNCI : Journal of the National Cancer Institute (05.01.2005)
Published in JNCI : Journal of the National Cancer Institute (05.01.2005)
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Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies
Tamm, R, Mägi, R, Tremmel, R, Winter, S, Mihailov, E, Smid, A, Möricke, A, Klein, K, Schrappe, M, Stanulla, M, Houlston, R, Weinshilboum, R, Mlinarič Raščan, Irena, Metspalu, A, Milani, L, Schwab, M, Schaeffeler, E
Published in Clinical pharmacology and therapeutics (01.05.2017)
Published in Clinical pharmacology and therapeutics (01.05.2017)
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Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide
Lowry, P W, Franklin, C L, Weaver, A L, Szumlanski, C L, Mays, D C, Loftus, E V, Tremaine, W J, Lipsky, J J, Weinshilboum, R M, Sandborn, W J
Published in Gut (01.11.2001)
Published in Gut (01.11.2001)
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SLC6A4 variation and citalopram response
Mrazek, D.A., Rush, A.J., Biernacka, J.M., O'Kane, D.J., Cunningham, J.M., Wieben, E.D., Schaid, D.J., Drews, M.S., Courson, V.L., Snyder, K.A., Black III, J.L., Weinshilboum, R.M.
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05.04.2009)
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05.04.2009)
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Pharmacogenetics of the mycophenolic acid targets inosine monophosphate dehydrogenases IMPDH1 and IMPDH2: gene sequence variation and functional genomics
Wu, T‐Y, Peng, Y, Pelleymounter, LL, Moon, I, Eckloff, BW, Wieben, ED, Yee, VC, Weinshilboum, RM
Published in British journal of pharmacology (01.12.2010)
Published in British journal of pharmacology (01.12.2010)
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New insights into the pharmacogenomics of antidepressant response from the GENDEP and STARD studies: rare variant analysis and high-density imputation
Fabbri, C, Tansey, K E, Perlis, R H, Hauser, J, Henigsberg, N, Maier, W, Mors, O, Placentino, A, Rietschel, M, Souery, D, Breen, G, Curtis, C, Sang-Hyuk, L, Newhouse, S, Patel, H, Guipponi, M, Perroud, N, Bondolfi, G, O'Donovan, M, Lewis, G, Biernacka, J M, Weinshilboum, R M, Farmer, A, Aitchison, K J, Craig, I, McGuffin, P, Uher, R, Lewis, C M
Published in The pharmacogenomics journal (22.05.2018)
Published in The pharmacogenomics journal (22.05.2018)
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