High detection rate of adenomas in familial colorectal cancer
van der Meulen-de Jong, A E, Morreau, H, Becx, M C J M, Crobach, L F S J, Haastert, M van, Hove, W R ten, Kleibeuker, J H, Meijssen, M A C, Nagengast, F M, Rijk, M C M, Salemans, J M J I, Stronkhorst, A, Tuynman, H A R E, Vecht, J, Verhulst, M L, de Vos tot Nederveen Cappel, W H, Walinga, H, Weinhardt, O K, Westerveld, B D, Witte, A M C, Wolters, H J, Vasen, H F A
Published in Gut (01.01.2011)
Published in Gut (01.01.2011)
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2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists
Clark, Robin D, Miller, Aaron B, Berger, Jacob, Repke, David B, Weinhardt, Klaus K, Kowalczyk, Bruce A, Eglen, Richard M, Bonhaus, Douglas W, Lee, Chi Ho
Published in Journal of medicinal chemistry (01.09.1993)
Published in Journal of medicinal chemistry (01.09.1993)
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RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist
Bonhaus, D W, Weinhardt, K K, Taylor, M, DeSouza, A, McNeeley, P M, Szczepanski, K, Fontana, D J, Trinh, J, Rocha, C L, Dawson, M W, Flippin, L A, Eglen, R M
Published in Neuropharmacology (01.04.1997)
Published in Neuropharmacology (01.04.1997)
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Randomized Comparison of Surveillance Intervals in Familial Colorectal Cancer
Hennink, Simone D, van der Meulen-de Jong, Andrea E, Wolterbeek, Ron, Crobach, A Stijn L P, Becx, Marco C J M, Crobach, Wiet F S J, van Haastert, Michiel, Ten Hove, W Rogier, Kleibeuker, Jan H, Meijssen, Maarten A C, Nagengast, Fokko M, Rijk, Marno C M, Salemans, Jan M J I, Stronkhorst, Arnold, Tuynman, Hans A R E, Vecht, Juda, Verhulst, Marie-Louise, de Vos Tot Nederveen Cappel, Wouter H, Walinga, Herman, Weinhardt, Olaf K, Westerveld, Dik, Witte, Anne M C, Wolters, Hugo J, Cats, Annemieke, Veenendaal, Roeland A, Morreau, Hans, Vasen, Hans F A
Published in Journal of clinical oncology (10.12.2015)
Published in Journal of clinical oncology (10.12.2015)
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1,9-Alkano-bridged 2,3,4,5-tetrahydro-1H-3-benzazepines with affinity for the alpha 2-adrenoceptor and the 5-HT1A receptor
Clark, R D, Weinhardt, K K, Berger, J, Fisher, L E, Brown, C M, MacKinnon, A C, Kilpatrick, A T, Spedding, M
Published in Journal of medicinal chemistry (01.02.1990)
Published in Journal of medicinal chemistry (01.02.1990)
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A new class of antimalarial drugs: derivatives of benzothiopyrans
Razdan, Raj K, Bruni, Robert J, Mehta, Avinash C, Weinhardt, Klaus K, Papanastassiou, Zinon B
Published in Journal of medicinal chemistry (01.07.1978)
Published in Journal of medicinal chemistry (01.07.1978)
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Synthesis and preliminary pharmacological evaluation of 2-benzyloxy substituted aryl ketones as 5-HT4 receptor antagonists
Clark, R.D., Jahangir, A., Langston, J.A., Weinhardt, K.K., Miller, A.B., Leung, E., Bonhaus, D.W., Wong, E.H.F., Eglen, R.M.
Published in Bioorganic & medicinal chemistry letters (01.10.1994)
Published in Bioorganic & medicinal chemistry letters (01.10.1994)
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Affinity of 2-(tetrahydroisoquinolin-2-ylmethyl)- and 2-(isoindolin-2-ylmethyl)imidazolines for α-adrenoceptors. Differential affinity of imidazolines for the [3H]idazoxan-labeled α2-adrenoceptor vs the [3H]yohimbine-labeled site
CLARK, R. D, BERGER, J, GARG, P, WEINHARDT, K. K, SPEDDING, M, KILPATRICK, A. T, BROWN, C. M, MACKINNON, A. C
Published in Journal of medicinal chemistry (1990)
Published in Journal of medicinal chemistry (1990)
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Aporphines. 8. Total Synthesis and Pharmacological Evaluation of (±)-Apomorphine, (±)-Apocodeine, (±)-N-n-Propylnorapomorphine, and (±)-N-n--Propylnorapocodeine
Neumeyer, John, Neustadt, Bernard, Oh, Kyung, Weinhardt, Klaus, Boyce, Charles, Rosenberg, Franklin, Teiger, David
Published in Journal of medicinal chemistry (01.11.1973)
Published in Journal of medicinal chemistry (01.11.1973)
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Isoquinolines. 3. 3-Aminoisoquinoline derivatives with central nervous system depressant activity
Neumeyer, J L, Weinhardt, K K, Carrano, R A, McCurdy, D H
Published in Journal of medicinal chemistry (01.07.1973)
Published in Journal of medicinal chemistry (01.07.1973)
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Aporphines. V. Total synthesis of (plus or minus)-apomorphine
Neumeyer, J L, Neustadt, B R, Weinhardt, K K
Published in Journal of pharmaceutical sciences (01.12.1970)
Published in Journal of pharmaceutical sciences (01.12.1970)
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Affinity of 2-(tetrahydroisoquinolin-2-ylmethyl)- and 2-(isoindolin-2-ylmethyl)imidazolines for .alpha.-adrenoceptors. Differential affinity of imidazolines for the [3H]idazoxan-labeled .alpha.2-adrenoceptor vs. the [3H]yohimbime-labeled site [Erratum to document cited in CA112(7):55713w
Clark, Robin D, Berger, Jacob, Garg, Pushkal, Weinhardt, Klaus K, Spedding, Michael, Kilpatrick, Andrew T, Brown, Christine M, MacKinnon, Alison C
Published in Journal of medicinal chemistry (01.09.1990)
Published in Journal of medicinal chemistry (01.09.1990)
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1,9-Alkano-bridged 2,3,4,5-tetrahydro-1H-3-benzazepines with affinity for the .alpha.2-adrenoceptor and the 5-HT1A receptor
Clark, Robin D, Weinhardt, Klaus K, Berger, Jacob, Fisher, Lawrence E, Brown, Christine M, MacKinnon, Alison C, Kilpatrick, Andrew T, Spedding, Michael
Published in Journal of medicinal chemistry (01.02.1990)
Published in Journal of medicinal chemistry (01.02.1990)
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Journal Article
Affinity of 2-(tetrahydroisoquinolin-2-ylmethyl)- and 2-(isoindolin-2-ylmethyl)imidazolines for .alpha.-adrenoceptors. Differential affinity of imidazolines for the [3H]idazoxan-labeled .alpha.2-adrenoceptor vs the [3H]yohimbine-labeled site
Clark, Robin D, Berger, Jacob, Garg, Pushkal, Weinhardt, Klaus K, Spedding, Michael, Kilpatrick, Andrew T, Brown, Christine M, MacKinnon, Alison C
Published in Journal of medicinal chemistry (01.02.1990)
Published in Journal of medicinal chemistry (01.02.1990)
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N-(Quinuclidin-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-oxo-acetamide: a high affinity 5-HT3 receptor partial agonist
Clark, R.D., Muchowski, J.M., Weinhardt, K.K., Dillon, M.P., Lee, C-H., Bley, K.R., Bonhaus, D.W., Wong, E.H.F., Eglen, R.M.
Published in Bioorganic & medicinal chemistry letters (17.08.1995)
Published in Bioorganic & medicinal chemistry letters (17.08.1995)
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