Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells
Wan, Weihua, Albom, Mark S., Lu, Lihui, Quail, Matthew R., Becknell, Nadine C., Weinberg, Linda R., Reddy, Dandu R., Holskin, Beverly P., Angeles, Thelma S., Underiner, Ted L., Meyer, Sheryl L., Hudkins, Robert L., Dorsey, Bruce D., Ator, Mark A., Ruggeri, Bruce A., Cheng, Mangeng
Published in Blood (15.02.2006)
Published in Blood (15.02.2006)
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Journal Article
Synthesis and structure–activity relationships of 1,2,3,4-tetrahydropyrido[2,3- b]pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase
Milkiewicz, Karen L., Weinberg, Linda R., Albom, Mark S., Angeles, Thelma S., Cheng, Mangeng, Ghose, Arup K., Roemmele, Renee C., Theroff, Jay P., Underiner, Ted L., Zificsak, Craig A., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry (15.06.2010)
Published in Bioorganic & medicinal chemistry (15.06.2010)
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Journal Article
Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors
Weinberg, Linda R., Albom, Mark S., Angeles, Thelma S., Husten, Jean, Lisko, Joseph G., McHugh, Robert J., Milkiewicz, Karen L., Murthy, Seetha, Ott, Gregory R., Theroff, Jay P., Tripathy, Rabindranath, Underiner, Ted L., Zificsak, Craig A., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Journal Article
2,7-Pyrrolo[2,1- f][1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formation
Weinberg, Linda R., Albom, Mark S., Angeles, Thelma S., Breslin, Henry J., Gingrich, Diane E., Huang, Zeqi, Lisko, Joseph G., Mason, Jennifer L., Milkiewicz, Karen L., Thieu, Tho V., Underiner, Ted L., Wells, Gregory J., Wells-Knecht, Kevin J., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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Journal Article
Improvement in oral bioavailability of 2,4-diaminopyrimidine c-Met inhibitors by incorporation of a 3-amidobenzazepin-2-one group
Milkiewicz, Karen L., Aimone, Lisa D., Albom, Mark S., Angeles, Thelma S., Chang, Hong, Grobelny, Jennifer V., Husten, Jean, LoSardo, Christine, Miknyoczki, Sheila, Murthy, Seetha, Rolon-Steele, Damaris, Underiner, Ted L., Weinberg, Linda R., Worrell, Candace S., Zeigler, Kelli S., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry (01.11.2011)
Published in Bioorganic & medicinal chemistry (01.11.2011)
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Journal Article
Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases
Zificsak, Craig A., Gingrich, Diane E., Breslin, Henry J., Dunn, Derek D., Milkiewicz, Karen L., Theroff, Jay P., Thieu, Tho V., Underiner, Ted L., Weinberg, Linda R., Aimone, Lisa D., Albom, Mark S., Mason, Jennifer L., Saville, Lisa, Husten, Jean, Angeles, Thelma S., Finn, James P., Jan, Mahfuza, O’Kane, Teresa M., Dobrzanski, Pawel, Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
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Journal Article
2,7-Disubstituted-Pyrrolotriazine Kinase Inhibitors with an Unusually High Degree of Reactive Metabolite Formation
Wells-Knecht, Kevin J, Ott, Gregory R, Cheng, Mangeng, Wells, Gregory J, Breslin, Henry J, Gingrich, Diane E, Weinberg, Linda, Mesaros, Eugen F, Huang, Zeqi, Yazdanian, Mehran, Ator, Mark A, Aimone, Lisa D, Zeigler, Kelli, Dorsey, Bruce D
Published in Chemical research in toxicology (21.11.2011)
Published in Chemical research in toxicology (21.11.2011)
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Journal Article
1,4-치환된 피페리딘 유도체
DANDU REDDEPPA REDDY, WEINBERG LINDA, GOTCHEV DIMITAR B, ZIFICSAK CRAIG A, BECKNELL NADINE C, ZULLI ALLISON L, DORSEY BRUCE D, HUDKINS ROBERT L
Year of Publication 12.03.2018
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Year of Publication 12.03.2018
Patent
Phase I Study of H5.020CMV.PDGF-[beta] to Treat Venous Leg Ulcer Disease
Margolis, David J, Morris, Lee M, Papadopoulos, Maryte, Weinberg, Linda, Filip, Jennifer C, Lang, Stephanie A, Vaikunth, Sachin S, Crombleholme, Timothy M
Published in Molecular therapy (01.10.2009)
Published in Molecular therapy (01.10.2009)
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Journal Article
TIE-2/VEGF-R2 SAR and in vitro activity of C3-acyl dihydroindazolo[5,4- a]pyrrolo[3,4- c]carbazole analogs
Underiner, Ted L., Ruggeri, Bruce, Aimone, Lisa, Albom, Mark, Angeles, Thelma, Chang, Hong, Hudkins, Robert L., Hunter, Kathryn, Josef, Kurt, Robinson, Candy, Weinberg, Linda, Yang, Shi, Zulli, Allison
Published in Bioorganic & medicinal chemistry (01.04.2008)
Published in Bioorganic & medicinal chemistry (01.04.2008)
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Journal Article
Clinical protocol. Phase I trial to evaluate the safety of H5.020CMV.PDGF-b and limb compression bandage for the treatment of venous leg ulcer: trial A
Margolis, David J, Cromblehome, Timothy, Herlyn, Meenhard, Cross, Philip, Weinberg, Linda, Filip, Jennifer, Propert, Kathleen
Published in Human gene therapy (01.10.2004)
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Published in Human gene therapy (01.10.2004)
Journal Article
Substituted 4-Benzyl And 4-Benzoyl Piperidine Derivates
Dorsey, Bruce D, Dandu, Reddeppa Reddy, Hudkins, Robert L, Weinberg, Linda, Becknell, Nadine C, Zificsak, Craig A, Gotchev, Dimitar B
Year of Publication 23.05.2024
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Year of Publication 23.05.2024
Patent
SUBSTITUTED 4-BENZYL AND 4-BENZOYL PIPERIDINE DERIVATIVES
BECKNELL, NADINE C, DANDU, REDDEPPA REDDY, DORSEY, BRUCE D, GOTCHEV, DIMITAR B, HUDKINS, ROBERT L, ZIFICSAK, CRAIG A, WEINBERG, LINDA
Year of Publication 07.05.2024
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Year of Publication 07.05.2024
Patent
Identification and Characterization of an ALK Inhibitor That Attenuates the Proliferation and Survival of Anaplastic Large Cell Lymphoma-Derived Cell Lines and ALK Dependent Cell Lines
Cheng, Mangeng, Wan, Weihua, Albom, Mark, Weinberg, Linda, Angeles, Thelma, Quail, Matthew, Lu, Lihui, Underiner, Ted, Hudkins, Robert, Ator, Mark, Ruggeri, Bruce
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Journal Article
Substituted 4-benzyl and 4-benzoyl piperidine derivates
Dorsey, Bruce D, Dandu, Reddeppa Reddy, Hudkins, Robert L, Weinberg, Linda, Becknell, Nadine C, Zificsak, Craig A, Gotchev, Dimitar B
Year of Publication 23.01.2024
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Year of Publication 23.01.2024
Patent