Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
Wei, Spencer C., Levine, Jacob H., Cogdill, Alexandria P., Zhao, Yang, Anang, Nana-Ama A.S., Andrews, Miles C., Sharma, Padmanee, Wang, Jing, Wargo, Jennifer A., Pe’er, Dana, Allison, James P.
Published in Cell (07.09.2017)
Published in Cell (07.09.2017)
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Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies
Wei, Spencer C., Anang, Nana-Ama A. S., Sharma, Roshan, Andrews, Miles C., Reuben, Alexandre, Levine, Jacob H., Cogdill, Alexandria P., Mancuso, James J., Wargo, Jennifer A., Pe’er, Dana, Allison, James P.
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
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Combination of PD-1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer
Ma, Ying, Li, Jun, Wang, Huamin, Chiu, Yulun, Kingsley, Charles V., Fry, David, Delaney, Samantha N., Wei, Spencer C., Zhang, Jianhua, Maitra, Anirban, Yee, Cassian
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2020)
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Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia
Gregus, Ann M, Dumlao, Darren S, Wei, Spencer C, Norris, Paul C, Catella, Laura C, Meyerstein, Flore G, Buczynski, Matthew W, Steinauer, Joanne J, Fitzsimmons, Bethany L, Yaksh, Tony L, Dennis, Edward A
Published in The FASEB journal (01.05.2013)
Published in The FASEB journal (01.05.2013)
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Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway
Wei, Spencer C., Fattet, Laurent, Tsai, Jeff H., Guo, Yurong, Pai, Vincent H., Majeski, Hannah E., Chen, Albert C., Sah, Robert L., Taylor, Susan S., Engler, Adam J., Yang, Jing
Published in Nature cell biology (01.05.2015)
Published in Nature cell biology (01.05.2015)
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T cells specific for α-myosin drive immunotherapy-related myocarditis
Axelrod, Margaret L., Meijers, Wouter C., Screever, Elles M., Qin, Juan, Carroll, Mary Grace, Sun, Xiaopeng, Tannous, Elie, Zhang, Yueli, Sugiura, Ayaka, Taylor, Brandie C., Hanna, Ann, Zhang, Shaoyi, Amancherla, Kaushik, Tai, Warren, Wright, Jordan J., Wei, Spencer C., Opalenik, Susan R., Toren, Abigail L., Rathmell, Jeffrey C., Ferrell, P. Brent, Phillips, Elizabeth J., Mallal, Simon, Johnson, Douglas B., Allison, James P., Moslehi, Javid J., Balko, Justin M.
Published in Nature (London) (24.11.2022)
Published in Nature (London) (24.11.2022)
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Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States
Wei, Spencer C., Sharma, Roshan, Anang, Nana-Ama A.S., Levine, Jacob H., Zhao, Yang, Mancuso, James J., Setty, Manu, Sharma, Padmanee, Wang, Jing, Pe’er, Dana, Allison, James P.
Published in Immunity (Cambridge, Mass.) (16.04.2019)
Published in Immunity (Cambridge, Mass.) (16.04.2019)
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Inhibition of spinal 15-LOX-1 attenuates TLR4-dependent, nonsteroidal anti-inflammatory drug–unresponsive hyperalgesia in male rats
Gregus, Ann M., Buczynski, Matthew W., Dumlao, Darren S., Norris, Paul C., Rai, Ganesha, Simeonov, Anton, Maloney, David J., Jadhav, Ajit, Xu, Qinghao, Wei, Spencer C., Fitzsimmons, Bethany L., Dennis, Edward A., Yaksh, Tony L.
Published in Pain (Amsterdam) (01.12.2018)
Published in Pain (Amsterdam) (01.12.2018)
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Checkpoint Blockade + Chemotherapy: the Right Combination for AML?
Wei, Spencer C, Mancuso, James J, Daver, Naval, Allison, James P
Published in Blood cancer discovery (01.11.2021)
Published in Blood cancer discovery (01.11.2021)
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Identification of a Guide RNA Targeting an Ultraconserved Element for Evaluation of Cas9 Genome Editors Across Mammalian Species
Gowen, Benjamin G, Khekare, Prachi, McCawley, Shannon R, Melton, Kory, Soares, Craig, Chan, Jean, Jani, Vihasi, Boivin, Pierre, Bans, Ashil, Leong, Weng-In, Cantor, Aaron J, Walleshauser, Jack, Otoupal, Peter B, Mepani, Rina J, Silverman, Adam P, Haak-Frendscho, Mary, Wei, Spencer C
Published in CRISPR journal (23.09.2024)
Published in CRISPR journal (23.09.2024)
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A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor-Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention
Wei, Spencer C, Meijers, Wouter C, Axelrod, Margaret L, Anang, Nana-Ama A S, Screever, Elles M, Wescott, Elizabeth C, Johnson, Douglas B, Whitley, Elizabeth, Lehmann, Lorenz, Courand, Pierre-Yves, Mancuso, James J, Himmel, Lauren E, Lebrun-Vignes, Benedicte, Wleklinski, Matthew J, Knollmann, Bjorn C, Srinivasan, Jayashree, Li, Yu, Atolagbe, Oluwatomisin T, Rao, Xiayu, Zhao, Yang, Wang, Jing, Ehrlich, Lauren I R, Sharma, Padmanee, Salem, Joe-Elie, Balko, Justin M, Moslehi, Javid J, Allison, James P
Published in Cancer discovery (01.03.2021)
Published in Cancer discovery (01.03.2021)
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Combination of PD1 Inhibitor and OX40 Agonist Induces Tumor Rejection and Immune Memory in Mouse Models of Pancreatic Cancer
Ma, Ying, Li, Jun, Wang, Huamin, Chiu, Yulun, Kingsley, Charles V., Fry, David, Delaney, Samantha N., Wei, Spencer C., Zhang, Jianhua, Maitra, Anirban, Yee, Cassian
Published in Gastroenterology (New York, N.Y. 1943) (14.03.2020)
Published in Gastroenterology (New York, N.Y. 1943) (14.03.2020)
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Journal Article
Abstract 592: Distinct cellular mechanisms mediate anti-CTLA-4 and anti-PD-1 checkpoint blockade
Wei, Spencer C., Levine, Jacob H., Pe'er, Dana, Allison, James P.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Negative costimulation constrains T cell differentiation
Wei, Spencer C., Sharma, Roshan, Anang, Nana-Ama, Levine, Jacob, Zhao, Yang, Wang, Jing, Pe’er, Dana, Allison, James P.
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Journal Article
Negative costimulation constrains T cell differentiation by imposing boundaries on possible cell states
Wei, Spencer C., Sharma, Roshan, Anang, Nana-Ama A.S., Levine, Jacob H., Zhao, Yang, Mancuso, James J., Setty, Manu, Sharma, Padmanee, Wang, Jing, Pe’er, Dana, Allison, James P.
Published in Immunity (Cambridge, Mass.) (26.03.2019)
Published in Immunity (Cambridge, Mass.) (26.03.2019)
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Journal Article
Inhibition of spinal 15-LOX-1 attenuates TLR4-dependent, NSAID-unresponsive hyperalgesia in male rats
Gregus, Ann M., Buczynski, Matthew W., Dumlao, Darren S., Norris, Paul C., Rai, Ganesha, Simeonov, Anton, Maloney, David J., Jadhav, Ajit, Xu, Qinghao, Wei, Spencer C., Fitzsimmons, Bethany L., Dennis, Edward A., Yaksh, Tony L.
Published in Pain (Amsterdam) (01.12.2018)
Published in Pain (Amsterdam) (01.12.2018)
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Journal Article