Targeting MCL-1 in cancer: current status and perspectives
Wang, Haolan, Guo, Ming, Wei, Hudie, Chen, Yongheng
Published in Journal of hematology and oncology (21.04.2021)
Published in Journal of hematology and oncology (21.04.2021)
Get full text
Journal Article
Targeting p53 pathways: mechanisms, structures and advances in therapy
Wang, Haolan, Guo, Ming, Wei, Hudie, Chen, Yongheng
Published in Signal transduction and targeted therapy (01.03.2023)
Published in Signal transduction and targeted therapy (01.03.2023)
Get full text
Journal Article
Farnesoid X receptor (FXR): Structures and ligands
Jiang, Longying, Zhang, Huajun, Xiao, Desheng, Wei, Hudie, Chen, Yongheng
Published in Computational and structural biotechnology journal (01.01.2021)
Published in Computational and structural biotechnology journal (01.01.2021)
Get full text
Journal Article
Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis
Wei, Hudie, Qu, Lingzhi, Dai, Shuyan, Li, Yun, Wang, Haolan, Feng, Yilu, Chen, Xiaojuan, Jiang, Longying, Guo, Ming, Li, Jun, Chen, Zhuchu, Chen, Lin, Zhang, Ye, Chen, Yongheng
Published in Nature communications (16.04.2021)
Published in Nature communications (16.04.2021)
Get full text
Journal Article
Structural insight into the ligand binding mechanism of aryl hydrocarbon receptor
Dai, Shuyan, Qu, Lingzhi, Li, Jun, Zhang, Ye, Jiang, Longying, Wei, Hudie, Guo, Ming, Chen, Xiaojuan, Chen, Yongheng
Published in Nature communications (20.10.2022)
Published in Nature communications (20.10.2022)
Get full text
Journal Article
Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity
Wei, Hudie, Wang, Haolan, Wang, Genxin, Qu, Lingzhi, Jiang, Longying, Dai, Shuyan, Chen, Xiaojuan, Zhang, Ye, Chen, Zhuchu, Li, Youjun, Guo, Ming, Chen, Yongheng
Published in Nature communications (18.07.2023)
Published in Nature communications (18.07.2023)
Get full text
Journal Article
Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade
Zhang, Fei, Wei, Hudie, Wang, Xiaoxiao, Bai, Yu, Wang, Pilin, Wu, Jiawei, Jiang, Xiaoyong, Wang, Yugang, Cai, Haiyan, Xu, Ting, Zhou, Aiwu
Published in Cell discovery (07.03.2017)
Published in Cell discovery (07.03.2017)
Get full text
Journal Article
Structure-based design of a dual-warhead covalent inhibitor of FGFR4
Chen, Xiaojuan, Li, Huiliang, Lin, Qianmeng, Dai, Shuyan, Yue, Sitong, Qu, Lingzhi, Li, Maoyu, Guo, Ming, Wei, Hudie, Li, Jun, Jiang, Longying, Xu, Guangyu, Chen, Yongheng
Published in Communications chemistry (17.03.2022)
Published in Communications chemistry (17.03.2022)
Get full text
Journal Article
Characterization of the cholangiocarcinoma drug pemigatinib against FGFR gatekeeper mutants
Lin, Qianmeng, Chen, Xiaojuan, Qu, Lingzhi, Guo, Ming, Wei, Hudie, Dai, Shuyan, Jiang, Longying, Chen, Yongheng
Published in Communications chemistry (22.08.2022)
Published in Communications chemistry (22.08.2022)
Get full text
Journal Article
Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors
Qu, Lingzhi, Chen, Xiaojuan, Wei, Hudie, Guo, Ming, Dai, Shuyan, Jiang, Longying, Li, Jun, Yue, Sitong, Chen, Zhuchu, Chen, Yongheng
Published in Communications chemistry (11.01.2022)
Published in Communications chemistry (11.01.2022)
Get full text
Journal Article
Corrigendum to: “Farnesoid X receptor (FXR): Structures and ligands” [Comput. Struct. Biotechnol. J. 19 (2021) 2148–2159]
Jiang, Longying, Zhang, Huajun, Xiao, Desheng, Wei, Hudie, Chen, Yongheng
Published in Computational and structural biotechnology journal (01.01.2022)
Published in Computational and structural biotechnology journal (01.01.2022)
Get full text
Journal Article
Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA
Jiang, Longying, Liu, Xueke, Liang, Xujun, Dai, Shuyan, Wei, Hudie, Guo, Ming, Chen, Zhuchu, Xiao, Desheng, Chen, Yongheng
Published in Computational and structural biotechnology journal (01.01.2023)
Published in Computational and structural biotechnology journal (01.01.2023)
Get full text
Journal Article
Structural basis and selectivity of sulfatinib binding to FGFR and CSF-1R
Lin, Qianmeng, Dai, Shuyan, Qu, Lingzhi, Lin, Hang, Guo, Ming, Wei, Hudie, Chen, Yongheng, Chen, Xiaojuan
Published in Communications chemistry (03.01.2024)
Published in Communications chemistry (03.01.2024)
Get full text
Journal Article
Author Correction: Structure-based design of a dual-warhead covalent inhibitor of FGFR4
Chen, Xiaojuan, Li, Huiliang, Lin, Qianmeng, Dai, Shuyan, Yue, Sitong, Qu, Lingzhi, Li, Maoyu, Guo, Ming, Wei, Hudie, Li, Jun, Jiang, Longying, Xu, Guangyu, Chen, Yongheng
Published in Communications chemistry (14.04.2022)
Published in Communications chemistry (14.04.2022)
Get full text
Journal Article
Structural insight into the macrocyclic inhibitor TPX-0022 of c-Met and c-Src
Qu, Lingzhi, Lin, Hang, Dai, Shuyan, Guo, Ming, Chen, Xiaojuan, Jiang, Longying, Zhang, Huajun, Li, Maoyu, Liang, Xunjun, Chen, Zhuchu, Wei, Hudie, Chen, Yongheng
Published in Computational and structural biotechnology journal (2023)
Published in Computational and structural biotechnology journal (2023)
Get full text
Journal Article
Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor
Jiang, Longying, Liu, Xueke, Wei, Hudie, Dai, Shuyan, Qu, Lingzhi, Chen, Xiaojuan, Guo, Ming, Chen, Yongheng
Published in Biochemical and biophysical research communications (05.03.2022)
Published in Biochemical and biophysical research communications (05.03.2022)
Get full text
Journal Article
Structural characterization of the DNA binding mechanism of retinoic acid-related orphan receptor gamma
Jiang, Longying, Liu, Xueke, Liang, Xujun, Dai, Shuyan, Wei, Hudie, Guo, Ming, Chen, Zhuchu, Xiao, Desheng, Chen, Yongheng
Published in Structure (London) (04.04.2024)
Published in Structure (London) (04.04.2024)
Get full text
Journal Article
Mechanism of forkhead transcription factors binding to a novel palindromic DNA site
Li, Jun, Dai, Shuyan, Chen, Xiaojuan, Liang, Xujun, Qu, Lingzhi, Jiang, Longying, Guo, Ming, Zhou, Zhan, Wei, Hudie, Zhang, Huajun, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Published in Nucleic acids research (06.04.2021)
Published in Nucleic acids research (06.04.2021)
Get full text
Journal Article
Structural basis for DNA recognition by FOXC2
Chen, Xiaojuan, Wei, Hudie, Li, Jun, Liang, Xujun, Dai, Shuyan, Jiang, Longying, Guo, Ming, Qu, Lingzhi, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Published in Nucleic acids research (23.04.2019)
Published in Nucleic acids research (23.04.2019)
Get full text
Journal Article