NPTX2 and cognitive dysfunction in Alzheimer's Disease
Xiao, Mei-Fang, Xu, Desheng, Craig, Michael T, Pelkey, Kenneth A, Chien, Chun-Che, Shi, Yang, Zhang, Juhong, Resnick, Susan, Pletnikova, Olga, Salmon, David, Brewer, James, Edland, Steven, Wegiel, Jerzy, Tycko, Benjamin, Savonenko, Alena, Reeves, Roger H, Troncoso, Juan C, McBain, Chris J, Galasko, Douglas, Worley, Paul F
Published in eLife (23.03.2017)
Published in eLife (23.03.2017)
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The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes
Wegiel, Jerzy, Kuchna, Izabela, Nowicki, Krzysztof, Imaki, Humi, Wegiel, Jarek, Marchi, Elaine, Ma, Shuang Yong, Chauhan, Abha, Chauhan, Ved, Bobrowicz, Teresa Wierzba, de Leon, Mony, Louis, Leslie A. Saint, Cohen, Ira L., London, Eric, Brown, W. Ted, Wisniewski, Thomas
Published in Acta neuropathologica (01.06.2010)
Published in Acta neuropathologica (01.06.2010)
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Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models
Mendioroz, Maite, Do, Catherine, Jiang, Xiaoling, Liu, Chunhong, Darbary, Huferesh K, Lang, Charles F, Lin, John, Thomas, Anna, Abu-Amero, Sayeda, Stanier, Philip, Temkin, Alexis, Yale, Alexander, Liu, Meng-Min, Li, Yang, Salas, Martha, Kerkel, Kristi, Capone, George, Silverman, Wayne, Yu, Y Eugene, Moore, Gudrun, Wegiel, Jerzy, Tycko, Benjamin
Published in Genome Biology (25.11.2015)
Published in Genome Biology (25.11.2015)
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Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome
Liu, Fei, Liang, Zhihou, Wegiel, Jerzy, Hwang, Yu-Wen, Iqbal, Khalid, Grundke-Iqbal, Inge, Ramakrishna, Narayan, Gong, Cheng-Xin
Published in The FASEB journal (01.09.2008)
Published in The FASEB journal (01.09.2008)
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Journal Article
Deficit of corpus callosum axons, reduced axon diameter and decreased area are markers of abnormal development of interhemispheric connections in autistic subjects
Wegiel, Jarek, Kaczmarski, Wojciech, Flory, Michael, Martinez-Cerdeno, Veronica, Wisniewski, Thomas, Nowicki, Krzysztof, Kuchna, Izabela, Wegiel, Jerzy
Published in Acta neuropathologica communications (19.12.2018)
Published in Acta neuropathologica communications (19.12.2018)
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Contribution of glial cells to the development of amyloid plaques in Alzheimer’s disease
Nagele, Robert G, Wegiel, Jerzy, Venkataraman, Venkat, Imaki, Humi, Wang, Kuo-Chiang, Wegiel, Jarek
Published in Neurobiology of aging (01.05.2004)
Published in Neurobiology of aging (01.05.2004)
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Conference Proceeding
Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome
Shi, Jianhua, Zhang, Tianyi, Zhou, Chunlei, Chohan, Muhammad Omar, Gu, Xiaosong, Wegiel, Jerzy, Zhou, Jianhua, Hwang, Yu-Wen, Iqbal, Khalid, Grundke-Iqbal, Inge, Gong, Cheng-Xin, Liu, Fei
Published in The Journal of biological chemistry (17.10.2008)
Published in The Journal of biological chemistry (17.10.2008)
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Enhanced accumulation of N-terminally truncated Aβ with and without pyroglutamate-11 modification in parvalbumin-expressing GABAergic neurons in idiopathic and dup15q11.2-q13 autism
Frackowiak, Janusz, Mazur-Kolecka, Bozena, Mehta, Pankaj, Wegiel, Jerzy
Published in Acta neuropathologica communications (28.04.2020)
Published in Acta neuropathologica communications (28.04.2020)
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Characterization of placental and decidual cell development in early pregnancy loss by single-cell RNA sequencing
Zheng, Yuhua, Pan, Jing, Xia, Chenglai, Chen, Haiying, Zhou, Huadong, Ju, Weina, Wegiel, Jerzy, Myatt, Leslie, Roberts, James M, Guo, Xiaoling, Zhong, Nanbert
Published in Cell & bioscience (08.10.2022)
Published in Cell & bioscience (08.10.2022)
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Developmental deficits and staging of dynamics of age associated Alzheimer's disease neurodegeneration and neuronal loss in subjects with Down syndrome
Wegiel, Jerzy, Flory, Michael, Kuchna, Izabela, Nowicki, Krzysztof, Wegiel, Jarek, Ma, Shuang Yong, Zhong, Nanbert, Bobrowicz, Teresa Wierzba, de Leon, Mony, Lai, Florence, Silverman, Wayne P, Wisniewski, Thomas
Published in Acta neuropathologica communications (04.01.2022)
Published in Acta neuropathologica communications (04.01.2022)
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Tau seeding activity in various regions of down syndrome brain assessed by two novel assays
Jin, Nana, Gu, Jianlan, Wu, Ruozhen, Chu, Dandan, Tung, Yunn Chyn, Wegiel, Jerzy, Wisniewski, Thomas, Gong, Cheng-Xin, Iqbal, Khalid, Liu, Fei
Published in Acta neuropathologica communications (05.09.2022)
Published in Acta neuropathologica communications (05.09.2022)
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Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection
Wang, Xiaochuan, Blanchard, Julie, Grundke-Iqbal, Inge, Wegiel, Jerzy, Deng, Han-Xiang, Siddique, Teepu, Iqbal, Khalid
Published in Acta neuropathologica (01.02.2014)
Published in Acta neuropathologica (01.02.2014)
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Effect of trichostatin A on gelsolin levels, proteolysis of amyloid precursor protein, and amyloid beta-protein load in the brain of transgenic mouse model of Alzheimer's disease
Yang, Wenzhong, Chauhan, Abha, Wegiel, Jerzy, Kuchna, Izabela, Gu, Feng, Chauhan, Ved
Published in Current Alzheimer research (01.12.2014)
Published in Current Alzheimer research (01.12.2014)
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Journal Article
Contribution of olivofloccular circuitry developmental defects to atypical gaze in autism
Wegiel, Jerzy, Kuchna, Izabela, Nowicki, Krzysztof, Imaki, Humi, Wegiel, Jarek, Yong Ma, Shuang, Azmitia, Efrain C, Banerjee, Probal, Flory, Michael, Cohen, Ira L, London, Eric, Ted Brown, W, Komich Hare, Carolyn, Wisniewski, Thomas
Published in Brain research (28.05.2013)
Published in Brain research (28.05.2013)
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Intracellular distribution of differentially phosphorylated dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A)
Kaczmarski, Wojciech, Barua, Madhabi, Mazur-Kolecka, Bozena, Frackowiak, Janusz, Dowjat, Wieslaw, Mehta, Pankaj, Bolton, David, Hwang, Yu-Wen, Rabe, Ausma, Albertini, Giorgio, Wegiel, Jerzy
Published in Journal of neuroscience research (01.02.2014)
Published in Journal of neuroscience research (01.02.2014)
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Journal Article
Brain-region-specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism
Wegiel, Jerzy, Flory, Michael, Kuchna, Izabela, Nowicki, Krzysztof, Ma, Shuang Yong, Imaki, Humi, Wegiel, Jarek, Cohen, Ira L, London, Eric, Brown, W Ted, Wisniewski, Thomas
Published in Acta neuropathologica communications (10.03.2014)
Published in Acta neuropathologica communications (10.03.2014)
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Journal Article
Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders
Wegiel, Jerzy, Frackowiak, Janusz, Mazur-Kolecka, Bozena, Schanen, N Carolyn, Cook, Jr, Edwin H, Sigman, Marian, Brown, W Ted, Kuchna, Izabela, Wegiel, Jarek, Nowicki, Krzysztof, Imaki, Humi, Ma, Shuang Yong, Chauhan, Abha, Chauhan, Ved, Miller, David L, Mehta, Pankaj D, Flory, Michael, Cohen, Ira L, London, Eric, Reisberg, Barry, de Leon, Mony J, Wisniewski, Thomas
Published in PloS one (02.05.2012)
Published in PloS one (02.05.2012)
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Effect of DYRK1A activity inhibition on development of neuronal progenitors isolated from Ts65Dn mice
Mazur-Kolecka, Bozena, Golabek, Adam, Kida, Elizabeth, Rabe, Ausma, Hwang, Yu-Wen, Adayev, Tatyana, Wegiel, Jerzy, Flory, Michael, Kaczmarski, Wojciech, Marchi, Elaine, Frackowiak, Janusz
Published in Journal of neuroscience research (01.05.2012)
Published in Journal of neuroscience research (01.05.2012)
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