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Nishida, Y, Maeda, A, Kim, M J, Cao, L, Kubota, Y, Ishizawa, J, AlRawi, A, Kato, Y, Iwama, A, Fujisawa, M, Matsue, K, Weetall, M, Dumble, M, Andreeff, M, Davis, T W, Branstrom, A, Kimura, S, Kojima, K
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Published in Blood cancer journal (New York) (17.02.2017)
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Phase 1 results of PTC596, a novel small molecule targeting cancer stem cells (CSCs) by reducing levels of BMI1 protein
Shapiro, G, Bedard, P, Infante, J, Bauer, T, Prawira, A, Laksin, O, Weetall, M, Baird, J, Branstrom, A, O'Mara, E, Spiegel, R
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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511 Identification of a Small Molecule (PTC596) That Preferentially Depletes Tumor Stem Cells by Reducing Levels of Functional BMI1 Protein
Davis, T.W, Lee, S, Dumble, M, Sydorenko, N, Baiazitov, R, Jung, S, Sheedy, J, Weetall, M, Moon, Y.C, Cao, L.X
Published in European journal of cancer (1990) (01.11.2012)
Published in European journal of cancer (1990) (01.11.2012)
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T.P.7 Small molecule compounds correct alternative splicing of the SMN2 gene and restore SMN protein expression and function
Naryshkin, N, Narasimhan, J, Dakka, A, Gabbeta, V, Haley, M, Jung, S, Crona, J, Vazirani, P, Furia, B, Qi, H, Woll, M, Lee, S, Choi, S, Koyama, H, Yang, T, Chen, G, Zhang, S, Zhang, N, Huang, S, Li, C, Turpoff, A, Hedrick, J, Zhao, X, Mollin, A, Zadel, M, Letinski, S, Paushkin, S, Kobayashi, D, McCarthy, K, Chen, K, Metzger, F, Ratni, H, Gerlach, I, Khwaja, O, Trifillis, P, Colacino, J, Babiak, J, Almstead, N, Peltz, S, Karp, G, Weetall, M, Welch, E
Published in Neuromuscular disorders : NMD (01.10.2012)
Published in Neuromuscular disorders : NMD (01.10.2012)
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P3.12 Small molecule compounds that correct alternative splicing of the SMN2 gene and restore SMN protein expression and function
Naryshkin, N.A, Narasimhan, J, Dakka, A, Gabbeta, V, Haley, M, Crona, J, Jung, S, Vazirani, P, Furia, B, Qi, H, Woll, M, Yang, T, Lee, S, Choi, S, Chen, G, Zhang, S, Zhang, N, Huang, S, Li, C, Turpoff, A, Hedrick, J, Zhao, X, Mollin, A, Letinski, S, Risher, N, Paushkin, S, Kobayashi, D, McCarthy, K, Pleiss, M, Chen, K, Almstead, N, Colacino, J, Babiak, J, Peltz, S, Karp, G, Weetall, M, Welch, E.M
Published in Neuromuscular disorders : NMD (01.10.2011)
Published in Neuromuscular disorders : NMD (01.10.2011)
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G.P.4.04 PTC Therapeutics identifies compounds that modulate SMN protein expression at the post-transcriptional level
Paushkin, S, Dakka, A, Khandker, L, Kaushal, R, Qi, H, Woll, M, Hedrick, J, Mollin, A, Moon, Y.M, Weetall, M, Welch, E
Published in Neuromuscular disorders : NMD (01.10.2008)
Published in Neuromuscular disorders : NMD (01.10.2008)
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1528TiP A phase II/III study evaluating the efficacy and safety of unesbulin in advanced leiomyosarcoma (SUNRISELMS)
Ingham, M., Blay, J-Y., Baird, J., D'Silva, D., O'Keefe, K., Kong, R., Spiegel, R., Wahba, M., Weetall, M.
Published in Annals of oncology (01.09.2022)
Published in Annals of oncology (01.09.2022)
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Absorption and disposition of a tripeptoid and a tetrapeptide in the rat
Wang, Yanfeng, Lin, Hanford, Tullman, Robert, Jewell Jr, Charles F., Weetall, Marla L., Tse, Francis L.S.
Published in Biopharmaceutics & drug disposition (01.03.1999)
Published in Biopharmaceutics & drug disposition (01.03.1999)
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Acute myeloid leukemia driven by the CALM-AF10 fusion gene is dependent on BMI1
Barbosa, Karina, Deshpande, Anagha, Chen, Bo-Rui, Ghosh, Anwesha, Sun, Younguk, Dutta, Sayantanee, Weetall, Marla, Dixon, Jesse, Armstrong, Scott A., Bohlander, Stefan K., Deshpande, Aniruddha J.
Published in Experimental hematology (01.06.2019)
Published in Experimental hematology (01.06.2019)
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Initial first-in-human phase 1 results of PTC596, a novel small molecule that targets cancer stem cells (CSCs) by reducing BMI1 protein levels
Shapiro, G., Infante, J., Bauer, T.M., Prawira, A., Bedard, P., Laskin, O., Weetall, M., Baird, J., O'Mara, E., Spiegel, R.
Published in Annals of oncology (01.10.2016)
Published in Annals of oncology (01.10.2016)
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452 - Phase 1 results of PTC596, a novel small molecule targeting cancer stem cells (CSCs) by reducing levels of BMI1 protein
Shapiro, G., Bedard, P., Infante, J., Bauer, T., Prawira, A., Laksin, O., Weetall, M., Baird, J., Branstrom, A., O'Mara, E., Spiegel, R.
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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PS1004 PTC299 IS A NOVEL DHODH INHIBITOR FOR USE IN TREATMENT OF AML
Weetall, M., Sheedy, J., Furia, B., Trotta, C., Baird, J., O’Mara, E., Spiegel, R., O’Keefe, K., Smallera‐Birns, I., Borthakur, G., Kojima, K., Amitkumar, P.
Published in HemaSphere (01.06.2019)
Published in HemaSphere (01.06.2019)
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S122 THE FIRST‐IN‐CLASS, ORALLY AVAILABLE BMI‐1 MODULATORS PTC‐028 AND PTC596 DISPLAY POTENT ACTIVITY IN PRE‐CLINICAL MODELS OF MULTIPLE MYELOMA
Bolomsky, A., Muller, J., Stangelberger, K., Lejeune, M., Arnold, D., Duray, E., Breid, H., Vrancken, L., Hübl, W., Willheim, M., Weetall, M., Branstrom, A., Zojer, N., Caers, J., Ludwig, H.
Published in HemaSphere (01.06.2019)
Published in HemaSphere (01.06.2019)
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Phase 1 studies assessing the safety, PK, and VEGF-modulating effects of PTC299, a novel VEGF expression inhibitor
Hirawat, S., Elfring, G. L., Northcutt, V. J., Paquette-Lamontagne, N., Davis, T., Weetall, M., Babiak, J., Miller, L. L.
Published in Journal of clinical oncology (20.06.2007)
Published in Journal of clinical oncology (20.06.2007)
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A Homogeneous Fluorometric Assay for Measuring Cell Adhesion to Immobilized Ligand Using V-Well Microtiter Plates
Weetall, Marla, Hugo, Ronald, Maida, Susan, West, Susan, Wattanasin, Sompong, Bouhel, Rochdi, Weitz-Schmidt, Gabriele, Lake, Philip, Friedman, Constance
Published in Analytical biochemistry (15.06.2001)
Published in Analytical biochemistry (15.06.2001)
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Improved binding of a bivalent single-chain immunotoxin results in increased efficacy for in vivo T-cell depletion
Thompson, J, Stavrou, S, Weetall, M, Hexham, J M, Digan, M E, Wang, Z, Woo, J H, Yu, Y, Mathias, A, Liu, Y Y, Ma, S, Gordienko, I, Lake, P, Neville, Jr, D M
Published in Protein engineering (01.12.2001)
Published in Protein engineering (01.12.2001)
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Immunologic pathways in a quantitative model of immunosuppression based on rejection of an allogeneic or xenogeneic tumor graft
Hammond-McKibben, Denise, Saulnier, Muriel, Zhang, Jin, Risher, Nicole, Lake, Philip, Weetall, Marla
Published in Transplantation (27.04.2005)
Published in Transplantation (27.04.2005)
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