Mapping the Binding Interface of VEGF and a Monoclonal Antibody Fab-1 Fragment with Fast Photochemical Oxidation of Proteins (FPOP) and Mass Spectrometry
Zhang, Ying, Wecksler, Aaron T., Molina, Patricia, Deperalta, Galahad, Gross, Michael L.
Published in Journal of the American Society for Mass Spectrometry (01.05.2017)
Published in Journal of the American Society for Mass Spectrometry (01.05.2017)
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Journal Article
Antibody–receptor interactions mediate antibody-dependent cellular cytotoxicity
Sun, Yue, Izadi, Saeed, Callahan, Matthew, Deperalta, Galahad, Wecksler, Aaron T.
Published in The Journal of biological chemistry (01.07.2021)
Published in The Journal of biological chemistry (01.07.2021)
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Journal Article
Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors
Hwang, Sung Hee, Wecksler, Aaron T., Zhang, Guodong, Morisseau, Christophe, Nguyen, Long V., Fu, Samuel H., Hammock, Bruce D.
Published in Bioorganic & medicinal chemistry letters (01.07.2013)
Published in Bioorganic & medicinal chemistry letters (01.07.2013)
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Journal Article
Structural basis for dual-mode inhibition of the ABC transporter MsbA
Ho, Hoangdung, Miu, Anh, Alexander, Mary Kate, Garcia, Natalie K., Oh, Angela, Zilberleyb, Inna, Reichelt, Mike, Austin, Cary D., Tam, Christine, Shriver, Stephanie, Hu, Huiyong, Labadie, Sharada S., Liang, Jun, Wang, Lan, Wang, Jian, Lu, Yan, Purkey, Hans E., Quinn, John, Franke, Yvonne, Clark, Kevin, Beresini, Maureen H., Tan, Man-Wah, Sellers, Benjamin D., Maurer, Till, Koehler, Michael F. T., Wecksler, Aaron T., Kiefer, James R., Verma, Vishal, Xu, Yiming, Nishiyama, Mireille, Payandeh, Jian, Koth, Christopher M.
Published in Nature (London) (01.05.2018)
Published in Nature (London) (01.05.2018)
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Journal Article
Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal
Storek, Kelly M., Auerbach, Marcy R., Shi, Handuo, Garcia, Natalie K., Sun, Dawei, Nickerson, Nicholas N., Vij, Rajesh, Lin, Zhonghua, Chiang, Nancy, Schneider, Kellen, Wecksler, Aaron T., Skippington, Elizabeth, Nakamura, Gerald, Seshasayee, Dhaya, Koerber, James T., Payandeh, Jian, Smith, Peter A., Rutherford, Steven T.
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (03.04.2018)
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Journal Article
Characterization of ELISA Antibody-Antigen Interaction using Footprinting-Mass Spectrometry and Negative Staining Transmission Electron Microscopy
Lin, Margaret, Krawitz, Denise, Callahan, Matthew D., Deperalta, Galahad, Wecksler, Aaron T.
Published in Journal of the American Society for Mass Spectrometry (01.05.2018)
Published in Journal of the American Society for Mass Spectrometry (01.05.2018)
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Journal Article
Synthesis and Structure−Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase
Hwang, Sung Hee, Wagner, Karen M, Morisseau, Christophe, Liu, Jun-Yan, Dong, Hua, Wecksler, Aaron T, Hammock, Bruce D
Published in Journal of medicinal chemistry (28.04.2011)
Published in Journal of medicinal chemistry (28.04.2011)
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Journal Article
Effect of ambient light on IgG1 monoclonal antibodies during drug product processing and development
Sreedhara, Alavattam, Yin, Jian, Joyce, Michael, Lau, Kimberly, Wecksler, Aaron T., Deperalta, Galahad, Yi, Li, John Wang, Y., Kabakoff, Bruce, Kishore, Ravuri S.K.
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2016)
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2016)
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Journal Article
Targeted degradation via direct 26S proteasome recruitment
Bashore, Charlene, Prakash, Sumit, Johnson, Matthew C., Conrad, Ryan J., Kekessie, Ivy A., Scales, Suzie J., Ishisoko, Noriko, Kleinheinz, Tracy, Liu, Peter S., Popovych, Nataliya, Wecksler, Aaron T., Zhou, Lijuan, Tam, Christine, Zilberleyb, Inna, Srinivasan, Rajini, Blake, Robert A., Song, Aimin, Staben, Steven T., Zhang, Yingnan, Arnott, David, Fairbrother, Wayne J., Foster, Scott A., Wertz, Ingrid E., Ciferri, Claudio, Dueber, Erin C.
Published in Nature chemical biology (01.01.2023)
Published in Nature chemical biology (01.01.2023)
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Journal Article
Epitope mapping of anti-drug antibodies to a clinical candidate bispecific antibody
Schick, 3rd, Arthur J, Lundin, Victor, Low, Justin, Peng, Kun, Vandlen, Richard, Wecksler, Aaron T
Published in mAbs (2022)
Published in mAbs (2022)
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Journal Article
Photodisruption of the Structurally Conserved Cys-Cys-Trp Triads Leads to Reduction-Resistant Scrambled Intrachain Disulfides in an IgG1 Monoclonal Antibody
Wecksler, Aaron T, Yin, Jian, Lee Tao, Paula, Kabakoff, Bruce, Sreedhara, Alavattam, Deperalta, Galahad
Published in Molecular pharmaceutics (02.04.2018)
Published in Molecular pharmaceutics (02.04.2018)
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Journal Article
Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms
Hecht, Elizabeth Sara, Mehta, Shrenik, Wecksler, Aaron T, Aguilar, Ben, Swanson, Nathaniel, Phung, Wilson, Dubey Kelsoe, Ananya, Benner, W Henry, Tesar, Devin, Kelley, Robert F, Sandoval, Wendy, Sreedhara, Alavattam
Published in mAbs (2022)
Published in mAbs (2022)
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Journal Article
Native MS and ECD Characterization of a Fab–Antigen Complex May Facilitate Crystallization for X-ray Diffraction
Zhang, Ying, Cui, Weidong, Wecksler, Aaron T., Zhang, Hao, Molina, Patricia, Deperalta, Galahad, Gross, Michael L.
Published in Journal of the American Society for Mass Spectrometry (01.07.2016)
Published in Journal of the American Society for Mass Spectrometry (01.07.2016)
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Journal Article
Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation[S]
Morisseau, Christophe, Wecksler, Aaron T., Deng, Catherine, Dong, Hua, Yang, Jun, Lee, Kin Sing S., Kodani, Sean D., Hammock, Bruce D.
Published in Journal of lipid research (01.06.2014)
Published in Journal of lipid research (01.06.2014)
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Journal Article
Physicochemical and biological impact of metal-catalyzed oxidation of IgG1 monoclonal antibodies and antibody-drug conjugates via reactive oxygen species
Glover, Zephania Kwong, Wecksler, Aaron, Aryal, Baikuntha, Mehta, Shrenik, Pegues, Melissa, Chan, Wayman, Lehtimaki, Mari, Luo, Allen, Sreedhara, Alavattam, Rao, V Ashutosh
Published in mAbs (2022)
Published in mAbs (2022)
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