Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids
Schuster, Brooke, Junkin, Michael, Kashaf, Sara Saheb, Romero-Calvo, Isabel, Kirby, Kori, Matthews, Jonathan, Weber, Christopher R, Rzhetsky, Andrey, White, Kevin P, Tay, Savaş
Published in Nature communications (19.10.2020)
Published in Nature communications (19.10.2020)
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OrganoID: A versatile deep learning platform for tracking and analysis of single-organoid dynamics
Matthews, Jonathan M, Schuster, Brooke, Kashaf, Sara Saheb, Liu, Ping, Ben-Yishay, Rakefet, Ishay-Ronen, Dana, Izumchenko, Evgeny, Shen, Le, Weber, Christopher R, Bielski, Margaret, Kupfer, Sonia S, Bilgic, Mustafa, Rzhetsky, Andrey, Tay, Savaş
Published in PLoS computational biology (01.11.2022)
Published in PLoS computational biology (01.11.2022)
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Tight junction pore and leak pathways: a dynamic duo
Shen, Le, Weber, Christopher R, Raleigh, David R, Yu, Dan, Turner, Jerrold R
Published in Annual review of physiology (01.01.2011)
Published in Annual review of physiology (01.01.2011)
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tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state
Shen, Le, Weber, Christopher R, Turner, Jerrold R
Published in The Journal of cell biology (19.05.2008)
Published in The Journal of cell biology (19.05.2008)
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Bifidobacteria Stabilize Claudins at Tight Junctions and Prevent Intestinal Barrier Dysfunction in Mouse Necrotizing Enterocolitis
Bergmann, Kelly R, Liu, Shirley X.L, Tian, Runlan, Kushnir, Anna, Turner, Jerrold R, Li, Hong-Lin, Chou, Pauline M, Weber, Christopher R, De Plaen, Isabelle G
Published in The American journal of pathology (01.05.2013)
Published in The American journal of pathology (01.05.2013)
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Dynamic modeling of the tight junction pore pathway
Weber, Christopher R., Turner, Jerrold R.
Published in Annals of the New York Academy of Sciences (01.06.2017)
Published in Annals of the New York Academy of Sciences (01.06.2017)
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Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity
Weber, Christopher R., Raleigh, David R., Su, Liping, Shen, Le, Sullivan, Erika A., Wang, Yingmin, Turner, Jerrold R.
Published in The Journal of biological chemistry (16.04.2010)
Published in The Journal of biological chemistry (16.04.2010)
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Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
Marchiando, Amanda M, Shen, Le, Graham, W. Vallen, Weber, Christopher R, Schwarz, Brad T, Austin, Jotham R. II, Raleigh, David R, Guan, Yanfang, Watson, Alastair J.M, Montrose, Marshall H, Turner, Jerrold R
Published in The Journal of cell biology (05.04.2010)
Published in The Journal of cell biology (05.04.2010)
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MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function
Yu, Dan, Marchiando, Amanda M, Weber, Christopher R, Raleigh, David R, Wang, Yingmin, Shen, Le, Turner, Jerrold R
Published in Proceedings of the National Academy of Sciences - PNAS (04.05.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (04.05.2010)
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Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function
Raleigh, David R, Boe, Devin M, Yu, Dan, Weber, Christopher R, Marchiando, Amanda M, Bradford, Emily M, Wang, Yingmin, Wu, Licheng, Schneeberger, Eveline E, Shen, Le, Turner, Jerrold R
Published in The Journal of cell biology (02.05.2011)
Published in The Journal of cell biology (02.05.2011)
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Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux
Buschmann, Mary M, Shen, Le, Rajapakse, Harsha, Raleigh, David R, Wang, Yitang, Wang, Yingmin, Lingaraju, Amulya, Zha, Juanmin, Abbott, Elliot, McAuley, Erin M, Breskin, Lydia A, Wu, Licheng, Anderson, Kenneth, Turner, Jerrold R, Weber, Christopher R
Published in Molecular biology of the cell (01.10.2013)
Published in Molecular biology of the cell (01.10.2013)
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Cerebral Cavernous Malformation Proteins in Barrier Maintenance and Regulation
Wei, Shu, Li, Ye, Polster, Sean P, Weber, Christopher R, Awad, Issam A, Shen, Le
Published in International journal of molecular sciences (20.01.2020)
Published in International journal of molecular sciences (20.01.2020)
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Dynamic migration of γδ intraepithelial lymphocytes requires occludin
Edelblum, Karen L, Shen, Le, Weber, Christopher R, Marchiando, Amanda M, Clay, Bryan S, Wang, Yingmin, Prinz, Immo, Malissen, Bernard, Sperling, Anne I, Turner, Jerrold R
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.2012)
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Claudin-2-dependent paracellular channels are dynamically gated
Weber, Christopher R, Liang, Guo Hua, Wang, Yitang, Das, Sudipto, Shen, Le, Yu, Alan S L, Nelson, Deborah J, Turner, Jerrold R
Published in eLife (14.11.2015)
Published in eLife (14.11.2015)
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Computational Modeling of Claudin Structure and Function
Fuladi, Shadi, Jannat, Ridaka-Wal, Shen, Le, Weber, Christopher R, Khalili-Araghi, Fatemeh
Published in International journal of molecular sciences (23.01.2020)
Published in International journal of molecular sciences (23.01.2020)
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AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling
Ferrarotto, Renata, Mishra, Vasudha, Herz, Elad, Yaacov, Adar, Solomon, Oz, Rauch, Rami, Mondshine, Adi, Motin, Maria, Leibovich-Rivkin, Tal, Davis, Matti, Kaye, Joel, Weber, Christopher R, Shen, Le, Pearson, Alexander T, Rosenberg, Ari J, Chen, Xiangying, Singh, Alka, Aster, Jon C, Agrawal, Nishant, Izumchenko, Evgeny
Published in Cell death & disease (05.08.2022)
Published in Cell death & disease (05.08.2022)
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Potential Dietary and Therapeutic Strategies Involving Indole-3-Carbinole in Preclinical Models of Intestinal Inflammation
Qazi, Aisha, Comiskey, Shane, Calzadilla, Nathan, Amin, Fatimah, Sharma, Anchal, Khin, Ei, Holton, Nathaniel, Weber, Christopher R, Saksena, Seema, Kumar, Anoop, Alrefai, Waddah A, Gill, Ravinder K
Published in Nutrients (30.11.2023)
Published in Nutrients (30.11.2023)
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