Selection and Evaluation of Tagging SNPs in the Neuronal-Sodium-Channel Gene SCN1A: Implications for Linkage-Disequilibrium Gene Mapping
Weale, Mike E., Depondt, Chantal, Macdonald, Stuart J., Smith, Alice, Lai, Poh San, Shorvon, Simon D., Wood, Nicholas W., Goldstein, David B.
Published in American journal of human genetics (01.09.2003)
Published in American journal of human genetics (01.09.2003)
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Journal Article
Phenome-wide association studies across large population cohorts support drug target validation
Diogo, Dorothée, Tian, Chao, Franklin, Christopher S., Alanne-Kinnunen, Mervi, March, Michael, Spencer, Chris C. A., Vangjeli, Ciara, Weale, Michael E., Mattsson, Hannele, Kilpeläinen, Elina, Sleiman, Patrick M. A., Reilly, Dermot F., McElwee, Joshua, Maranville, Joseph C., Chatterjee, Arnaub K., Bhandari, Aman, Nguyen, Khanh-Dung H., Estrada, Karol, Reeve, Mary-Pat, Hutz, Janna, Bing, Nan, John, Sally, MacArthur, Daniel G., Salomaa, Veikko, Ripatti, Samuli, Hakonarson, Hakon, Daly, Mark J., Palotie, Aarno, Hinds, David A., Donnelly, Peter, Fox, Caroline S., Day-Williams, Aaron G., Plenge, Robert M., Runz, Heiko
Published in Nature communications (16.10.2018)
Published in Nature communications (16.10.2018)
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Journal Article
Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter Gene ABCB1
Siddiqui, Asra, Kerb, Reinhold, Weale, Michael E, Brinkmann, Ulrich, Smith, Alice, Goldstein, David B, Wood, Nicholas W, Sisodiya, Sanjay M
Published in The New England journal of medicine (10.04.2003)
Published in The New England journal of medicine (10.04.2003)
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Journal Article
Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis
KNIGHT, Jo, SPAIN, Sarah L, CAPON, Francesca, HAYDAY, Adrian, NESTLE, Frank O, CLOP, Alex, BARKER, Jonathan N, WEALE, Michael E, TREMBATH, Richard C
Published in Human molecular genetics (01.12.2012)
Published in Human molecular genetics (01.12.2012)
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Journal Article
Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain
Hernandez, Dena G, Nalls, Mike A, Moore, Matthew, Chong, Sean, Dillman, Allissa, Trabzuni, Daniah, Gibbs, J. Raphael, Ryten, Mina, Arepalli, Sampath, Weale, Michael E, Zonderman, Alan B, Troncoso, Juan, O'Brien, Richard, Walker, Robert, Smith, Colin, Bandinelli, Stefania, Traynor, Bryan J, Hardy, John, Singleton, Andrew B, Cookson, Mark R
Published in Neurobiology of disease (01.07.2012)
Published in Neurobiology of disease (01.07.2012)
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Journal Article
A novel polymorphism associated with lactose tolerance in Africa : multiple causes for lactase persistence?
INGRAM, Catherine J. E, ELAMIN, Mohamed F, SWALLOW, Dallas M, MULCARE, Charlotte A, WEALE, Michael E, TAREKEGN, Ayele, OLJIRA RAGA, Tamiru, BEKELE, Endashaw, ELAMIN, Farouk M, THOMAS, Mark G, BRADMAN, Neil
Published in Human genetics (01.02.2007)
Published in Human genetics (01.02.2007)
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Journal Article
Positive Selection on a High-Sensitivity Allele of the Human Bitter-Taste Receptor TAS2R16
Soranzo, Nicole, Bufe, Bernd, Sabeti, Pardis C., Wilson, James F., Weale, Michael E., Marguerie, Richard, Meyerhof, Wolfgang, Goldstein, David B.
Published in Current biology (26.07.2005)
Published in Current biology (26.07.2005)
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Journal Article
Population genetic structure of variable drug response
Goldstein, David B, Wilson, James F, Weale, Michael E, Smith, Alice C, Gratrix, Fiona, Fletcher, Benjamin, Thomas, Mark G, Bradman, Neil
Published in Nature genetics (01.11.2001)
Published in Nature genetics (01.11.2001)
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Journal Article
Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours
Khalique, L, Ayhan, A, Weale, ME, Jacobs, IJ, Ramus, SJ, Gayther, SA
Published in The Journal of pathology (01.02.2007)
Published in The Journal of pathology (01.02.2007)
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Journal Article
The T Allele of a Single-Nucleotide Polymorphism 13.9 kb Upstream of the Lactase Gene ( LCT) ( C−13.9kbT) Does Not Predict or Cause the Lactase-Persistence Phenotype in Africans
Mulcare, Charlotte A., Weale, Michael E., Jones, Abigail L., Connell, Bruce, Zeitlyn, David, Tarekegn, Ayele, Swallow, Dallas M., Bradman, Neil, Thomas, Mark G.
Published in American journal of human genetics (01.06.2004)
Published in American journal of human genetics (01.06.2004)
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Journal Article
A single-nucleotide polymorphism tagging set for human drug metabolism and transport
Goldstein, David B, Ahmadi, Kourosh R, Weale, Mike E, Xue, Zhengyu Y, Soranzo, Nicole, Yarnall, David P, Briley, James D, Maruyama, Yuka, Kobayashi, Mikiro, Wood, Nicholas W, Spurr, Nigel K, Burns, Daniel K, Roses, Allen D, Saunders, Ann M
Published in Nature genetics (01.01.2005)
Published in Nature genetics (01.01.2005)
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Journal Article
Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci
Holton, Patrick, Ryten, Mina, Nalls, Michael, Trabzuni, Daniah, Weale, Michael E., Hernandez, Dena, Crehan, Helen, Gibbs, J. Raphael, Mayeux, Richard, Haines, Jonathan L., Farrer, Lindsay A., Pericak‐Vance, Margaret A., Schellenberg, Gerard D., Ramirez‐Restrepo, Manuel, Engel, Anzhelika, Myers, Amanda J., Corneveaux, Jason J., Huentelman, Matthew J., Dillman, Allissa, Cookson, Mark R., Reiman, Eric M., Singleton, Andrew, Hardy, John, Guerreiro, Rita
Published in Annals of human genetics (01.03.2013)
Published in Annals of human genetics (01.03.2013)
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Journal Article
Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene
Soranzo, Nicole, Cavalleri, Gianpiero L, Weale, Michael E, Wood, Nicholas W, Depondt, Chantal, Marguerie, Richard, Sisodiya, Sanjay M, Goldstein, David B
Published in Genome research (01.07.2004)
Published in Genome research (01.07.2004)
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Journal Article
Genetic determinants of variable metabolism have little impact on the clinical use of leading antipsychotics in the CATIE study
Grossman, Iris, Sullivan, Patrick F., Walley, Nicole, Liu, Youfang, Dawson, Jeffrey R., Gumbs, Curtis, Gaedigk, Andrea, Leeder, J. Steven, McEvoy, Joseph P., Weale, Michael E., Goldstein, David B.
Published in Genetics in medicine (01.10.2008)
Published in Genetics in medicine (01.10.2008)
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Journal Article
Y chromosome evidence for Anglo-Saxon mass migration
Weale, Michael E, Weiss, Deborah A, Jager, Rolf F, Bradman, Neil, Thomas, Mark G
Published in Molecular biology and evolution (01.07.2002)
Published in Molecular biology and evolution (01.07.2002)
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Journal Article
Founding Mothers of Jewish Communities: Geographically Separated Jewish Groups Were Independently Founded by Very Few Female Ancestors
Thomas, Mark G., Weale, Michael E., Jones, Abigail L., Richards, Martin, Smith, Alice, Redhead, Nicola, Torroni, Antonio, Scozzari, Rosaria, Gratrix, Fiona, Tarekegn, Ayele, Wilson, James F., Capelli, Cristian, Bradman, Neil, Goldstein, David B.
Published in American journal of human genetics (01.06.2002)
Published in American journal of human genetics (01.06.2002)
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Journal Article